Computational modeling predicts ephemeral acidic microdomains in the glutamatergic synaptic cleft

Neuronal Glutamatergic Synaptic Clefts Alkalinize Rather Than Acidify during Neurotransmission

(2020) Michal Stawarski et al.   JOURNAL OF NEUROSCIENCE

LTP Induction Boosts Glutamate Spillover by Driving Withdrawal of Perisynaptic Astroglia

(2020) Christian Henneberger et al.   NEURON

Protein kinase C lambda mediates acid-sensing ion channel 1a-dependent cortical synaptic plasticity and pain hypersensitivity

(2019) Hu-Song Li et al.   JOURNAL OF NEUROSCIENCE

Acid-Base Basics

(2019) Michael F. Romero et al.   SEMINARS IN NEPHROLOGY

Role of Carbonic Anhydrases and Inhibitors in Acid–Base Physiology: Insights from Mathematical Modeling

(2019) Occhipinti et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Counting the Number of Glutamate Molecules in Single Synaptic Vesicles

(2019) Yuanmo Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The application of ‘kisser’ probes for resolving the distribution and microenvironment of membrane proteins in situ

(2018) Michal Stawarski et al.   JOURNAL OF NEUROGENETICS

Localizing proton-mediated inhibitory feedback at the retinal horizontal cell-cone synapse with genetically-encoded pH probes

(2018) Billie Beckwith-Cohen et al.   JOURNAL OF NEUROSCIENCE

Clustered Ca2+ Channels Are Blocked by Synaptic Vesicle Proton Release at Mammalian Auditory Ribbon Synapses

(2018) Philippe F.Y. Vincent et al.   Cell Reports

Acid-Sensing Ion Channels Activated by Evoked Released Protons Modulate Synaptic Transmission at the Mouse Calyx of Held Synapse

(2017) Carlota González-Inchauspe et al.   JOURNAL OF NEUROSCIENCE

Electrodiffusion phenomena in neuroscience: a neglected companion

(2017) Leonid P. Savtchenko et al.   NATURE REVIEWS NEUROSCIENCE

Input-Specific Plasticity and Homeostasis at the Drosophila Larval Neuromuscular Junction

(2017) Zachary L. Newman et al.   NEURON

Deactivation kinetics of acid-sensing ion channel 1a are strongly pH-sensitive

(2017) David M. MacLean et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nanoscale diffusion in the synaptic cleft and beyond measured with time-resolved fluorescence anisotropy imaging

(2017) Kaiyu Zheng et al.   Scientific Reports

High-Probability Neurotransmitter Release Sites Represent an Energy-Efficient Design

(2016) Zhongmin Lu et al.   CURRENT BIOLOGY

Three-dimensional imaging of Drosophila motor synapses reveals ultrastructural organizational patterns

(2016) Hong Zhan et al.   JOURNAL OF NEUROGENETICS

Acid-sensing ion channels are tuned to follow high-frequency stimuli

(2016) David M. MacLean et al.   JOURNAL OF PHYSIOLOGY-LONDON

Emerging roles of Na+/H+ exchangers in epilepsy and developmental brain disorders

(2016) Hanshu Zhao et al.   PROGRESS IN NEUROBIOLOGY

Maturation of active zone assembly byDrosophilaBruchpilot

(2016) Wernher Fouquet et al.   JOURNAL OF CELL BIOLOGY

Autocrine Boost of NMDAR Current in Hippocampal CA1 Pyramidal Neurons by a PMCA-Dependent, Perisynaptic, Extracellular pH Shift

(2015) H.-Y. Chen et al.   JOURNAL OF NEUROSCIENCE

Evidence from mathematical modeling that carbonic anhydrase II and IV enhance CO2 fluxes across Xenopus oocyte plasma membranes

(2014) Rossana Occhipinti et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Evoked and Spontaneous Transmission Favored by Distinct Sets of Synapses

(2014) Einat S. Peled et al.   CURRENT BIOLOGY

Proton-Mediated Block of Ca2+ Channels during Multivesicular Release Regulates Short-Term Plasticity at an Auditory Hair Cell Synapse

(2014) S. Cho et al.   JOURNAL OF NEUROSCIENCE

Imaging an optogenetic pH sensor reveals that protons mediate lateral inhibition in the retina

(2014) Tzu-Ming Wang et al.   NATURE NEUROSCIENCE

Acid-sensing ion channels contribute to synaptic transmission and inhibit cocaine-evoked plasticity

(2014) Collin J Kreple et al.   NATURE NEUROSCIENCE

Protons are a neurotransmitter that regulates synaptic plasticity in the lateral amygdala

(2014) J. Du et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intracellular pH regulation by acid-base transporters in mammalian neurons

(2014) Vernon A. Ruffin et al.   Frontiers in Physiology

Minireview: pH and synaptic transmission

(2013) Anne Sinning et al.   FEBS LETTERS

Acid-sensing ion channels in pain and disease

(2013) John A. Wemmie et al.   NATURE REVIEWS NEUROSCIENCE

Spike-Driven Glutamate Electrodiffusion Triggers Synaptic Potentiation via a Homer-Dependent mGluR-NMDAR Link

(2013) Sergiy Sylantyev et al.   NEURON

Acid-sensing ion channels: trafficking and synaptic function

(2013) Xiang-ming Zha   Molecular Brain

Acidification of the synaptic cleft of cone photoreceptor terminal controls the amount of transmitter release, thereby forming the receptive field surround in the vertebrate retina

(2012) Hajime Hirasawa et al.   Journal of Physiological Sciences

A reaction–diffusion model of CO2 influx into an oocyte

(2012) Erkki Somersalo et al.   JOURNAL OF THEORETICAL BIOLOGY

Characterization of postsynaptic Ca2+ signals at the Drosophila larval NMJ

(2011) Sunil A. Desai et al.   JOURNAL OF NEUROPHYSIOLOGY

Rapid Rise of Extracellular pH Evoked by Neural Activity Is Generated by the Plasma Membrane Calcium ATPase

(2009) Sachin Makani et al.   JOURNAL OF NEUROPHYSIOLOGY

Calcium Pumps in Health and Disease

(2009) Marisa Brini et al.   PHYSIOLOGICAL REVIEWS

The plasma membrane calcium ATPase (PMCA) of neurones is electroneutral and exchanges 2 H+for each Ca2+or Ba2+ion extruded

(2008) Roger C. Thomas   JOURNAL OF PHYSIOLOGY-LONDON

Electric Fields Due to Synaptic Currents Sharpen Excitatory Transmission

(2008) S. Sylantyev et al.   SCIENCE

Regulation of pH in the mammalian central nervous system under normal and pathological conditions: Facts and hypotheses

(2007) Marta Obara et al.   NEUROCHEMISTRY INTERNATIONAL