Acid-sensing ion channels: trafficking and synaptic function

Physiological and Pathological Functions of Acid-Sensing Ion Channels in the Central Nervous System

(2012) Xiang-Ping Chu et al.   CURRENT DRUG TARGETS

A stomatin dimer modulates the activity of acid-sensing ion channels

(2012) Janko Brand et al.   EMBO JOURNAL

Impact of Recovery from Desensitization on Acid-sensing Ion Channel-1a (ASIC1a) Current and Response to High Frequency Stimulation

(2012) Tianbo Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lignan from Thyme Possesses Inhibitory Effect on ASIC3 Channel Current

(2012) Maxim A. Dubinnyi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PI3-kinase/Akt Pathway-Regulated Membrane Insertion of Acid-Sensing Ion Channel 1a Underlies BDNF-Induced Pain Hypersensitivity

(2012) B. Duan et al.   JOURNAL OF NEUROSCIENCE

N-Glycosylation of Acid-Sensing Ion Channel 1a Regulates Its Trafficking and Acidosis-Induced Spine Remodeling

(2012) L. Jing et al.   JOURNAL OF NEUROSCIENCE

Structural plasticity and dynamic selectivity of acid-sensing ion channel–spider toxin complexes

(2012) Isabelle Baconguis et al.   NATURE

Black mamba venom peptides target acid-sensing ion channels to abolish pain

(2012) Sylvie Diochot et al.   NATURE

Human ASIC3 channel dynamically adapts its activity to sense the extracellular pH in both acidic and alkaline directions

(2012) A. Delaunay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of ASIC channels by a stomatin/STOML3 complex located in a mobile vesicle pool in sensory neurons

(2012) L. Lapatsina et al.   Open Biology

Acid-sensing ion channel 1 is involved in both axonal injury and demyelination in multiple sclerosis and its animal model

(2011) Sandra Vergo et al.   BRAIN

A Kinase Anchor Protein 150 (AKAP150)-associated Protein Kinase A Limits Dendritic Spine Density

(2011) Yuan Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heteromeric Acid-Sensing Ion Channels (ASICs) Composed of ASIC2b and ASIC1a Display Novel Channel Properties and Contribute to Acidosis-Induced Neuronal Death

(2011) T. W. Sherwood et al.   JOURNAL OF NEUROSCIENCE

Extracellular Spermine Exacerbates Ischemic Neuronal Injury through Sensitization of ASIC1a Channels to Extracellular Acidosis

(2011) B. Duan et al.   JOURNAL OF NEUROSCIENCE

A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain

(2011) Christopher J. Bohlen et al.   NATURE

The Interaction between the First Transmembrane Domain and the Thumb of ASIC1a Is Critical for Its N-Glycosylation and Trafficking

(2011) Lan Jing et al.   PLoS One

PICK1 regulates the trafficking of ASIC1a and acidotoxicity in a BAR domain lipid binding-dependent manner

(2011) Wenying Jin et al.   Molecular Brain

Disruption of PICK1 attenuates the function of ASICs and PKC regulation of ASICs

(2010) Zhuang-Li Hu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Activation of Acid-sensing Ion Channel 1a (ASIC1a) by Surface Trafficking

(2010) Sunghee Chai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acid-Sensing Ion Channels in Acidosis-Induced Injury of Human Brain Neurons

(2010) Minghua Li et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Cell Type-Specific Expression of Acid-Sensing Ion Channels in Hippocampal Interneurons

(2010) J. Y. Weng et al.   JOURNAL OF NEUROSCIENCE

Developmental change in the electrophysiological and pharmacological properties of acid-sensing ion channels in CNS neurons

(2010) Minghua Li et al.   JOURNAL OF PHYSIOLOGY-LONDON

A Nonproton Ligand Sensor in the Acid-Sensing Ion Channel

(2010) Ye Yu et al.   NEURON

Current perspectives on acid-sensing ion channels: new advances and therapeutic implications

(2010) Jacques Noël et al.   Expert Review of Clinical Pharmacology

Native and recombinant ASIC1a receptors conduct negligible Ca2+ entry

(2009) Damien S.K. Samways et al.   CELL CALCIUM

Dynorphin Opioid Peptides Enhance Acid-Sensing Ion Channel 1a Activity and Acidosis-Induced Neuronal Death

(2009) T. W. Sherwood et al.   JOURNAL OF NEUROSCIENCE

ASIC2 Subunits Target Acid-Sensing Ion Channels to the Synapse via an Association with PSD-95

(2009) X.-m. Zha et al.   JOURNAL OF NEUROSCIENCE

Pore architecture and ion sites in acid-sensing ion channels and P2X receptors

(2009) Eric B. Gonzales et al.   NATURE

Characterization of acid-sensing ion channels in medium spiny neurons of mouse striatum

(2009) Q. Jiang et al.   NEUROSCIENCE

Oxidant regulated inter-subunit disulfide bond formation between ASIC1a subunits

(2009) X.-m. Zha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acid-sensing ion channel 3 (ASIC3) cell surface expression is modulated by PSD-95 within lipid rafts

(2008) Jayasheel O. Eshcol et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Hsc70 regulates cell surface ASIC2 expression and vascular smooth muscle cell migration

(2008) Samira C. Grifoni et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Differential effects of N-glycans on surface expression suggest structural differences between the acid-sensing ion channel (ASIC) 1a and ASIC1b

(2008) Ivan Kadurin et al.   BIOCHEMICAL JOURNAL

 -1 Receptor Modulation of Acid-Sensing Ion Channel a (ASIC1a) and ASIC1a-Induced Ca2+ Influx in Rat Cortical Neurons

(2008) Y. Herrera et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Seizure termination by acidosis depends on ASIC1a

(2008) Adam E Ziemann et al.   NATURE NEUROSCIENCE

Presynaptic Release Probability Is Increased in Hippocampal Neurons From ASIC1 Knockout Mice

(2007) Jun-Hyeong Cho et al.   JOURNAL OF NEUROPHYSIOLOGY

ASIC proteins regulate smooth muscle cell migration

(2007) Samira C. Grifoni et al.   MICROVASCULAR RESEARCH