Biological effects of bis-hydrazone compounds bearing isovanillin moiety on the aldose reductase

Synthesis, Characterization, and Inhibition Study of Novel Substituted Phenylureido Sulfaguanidine Derivatives as α‐Glycosidase and Cholinesterase Inhibitors

(2021) Suleyman Akocak et al.   CHEMISTRY & BIODIVERSITY

Novel inhibitors with sulfamethazine backbone: synthesis and biological study of multi-target cholinesterases and α-glucosidase inhibitors

(2021) Cüneyt Türkeş et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Synthesis, biological activity and docking calculations of bis-naphthoquinone derivatives from Lawsone

(2021) Muhammad Tariq Riaz et al.   BIOORGANIC CHEMISTRY

Design, synthesis, characterization, in vitro and in silico evaluation of novel imidazo[2,1-b][1,3,4]thiadiazoles as highly potent acetylcholinesterase and non-classical carbonic anhydrase inhibitors

(2021) Sercan Askin et al.   BIOORGANIC CHEMISTRY

Molecular docking and inhibition studies of vulpinic, carnosic and usnic acids on polyol pathway enzymes

(2021) Yeliz Demir et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Transition‐Metal Complexes of Bidentate Schiff‐Base Ligands: In Vitro and In Silico Evaluation as Non‐Classical Carbonic Anhydrase and Potential Acetylcholinesterase Inhibitors

(2021) Ümit Yaşar et al.   ChemistrySelect

Development of coumarin-thiosemicarbazone hybrids as aldose reductase inhibitors: Biological assays, molecular docking, simulation studies and ADME evaluation

(2021) Aqeel Imran et al.   BIOORGANIC CHEMISTRY

Molecular Docking Studies and Inhibition Properties of Some Antineoplastic Agents against Paraoxonase-I

(2020) Yeliz Demir et al.   Anti-Cancer Agents in Medicinal Chemistry

Calcium Channel Blockers: Molecular Docking and Inhibition Studies on Carbonic Anhydrase I and II Isoenzymes

(2020) Cüneyt Türkeş et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Sulfonamides incorporating ketene N,S -acetal bioisosteres as potent carbonic anhydrase and acetylcholinesterase inhibitors

(2020) Qëndresa Istrefi et al.   ARCHIV DER PHARMAZIE

In vitro studies of potent aldose reductase inhibitors: Synthesis, characterization, biological evaluation and docking analysis of rhodanine-3-hippuric acid derivatives

(2020) Stephen Kumar Celestina et al.   BIOORGANIC CHEMISTRY

Naphthoquinones, benzoquinones, and anthraquinones: Molecular docking, ADME and inhibition studies on human serum paraoxonase-1 associated with cardiovascular diseases

(2020) Yeliz Demir   DRUG DEVELOPMENT RESEARCH

Some sulfonamides as aldose reductase inhibitors: therapeutic approach in diabetes

(2020) Yeliz Demir et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Synthesis, characterization, biological evaluation, and in silico studies of novel 1,3‐diaryltriazene‐substituted sulfathiazole derivatives

(2020) Mesut Işık et al.   ARCHIV DER PHARMAZIE

Determination of the inhibition profiles of pyrazolyl–thiazole derivatives against aldose reductase and α‐glycosidase and molecular docking studies

(2020) Yeliz Demir et al.   ARCHIV DER PHARMAZIE

Synthesis, bioactivity and binding energy calculations of novel 3-ethoxysalicylaldehyde based thiosemicarbazone derivatives

(2020) Muhammad Ishaq et al.   BIOORGANIC CHEMISTRY

Synthesis, characterization, inhibition effects, and molecular docking studies as acetylcholinesterase, α-glycosidase, and carbonic anhydrase inhibitors of novel benzenesulfonamides incorporating 1,3,5-triazine structural motifs

(2020) Nebih Lolak et al.   BIOORGANIC CHEMISTRY

Some calcium-channel blockers: kinetic and in silico studies on paraoxonase-I

(2020) Cüneyt Türkeş et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Design, synthesis, in vitro and in silico investigation of aldose reductase inhibitory effects of new thiazole-based compounds

(2020) Belgin Sever et al.   BIOORGANIC CHEMISTRY

Investigation of Potential Paraoxonase-I Inhibitors by Kinetic and Molecular Docking Studies: Chemotherapeutic Drugs

(2019) Cüneyt Türkeş   PROTEIN AND PEPTIDE LETTERS

Towards more effective acetylcholinesterase inhibitors: a comprehensive modelling study based on human acetylcholinesterase protein–drug complex

(2019) Abdulilah Ece   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Designing of acyl sulphonamide based quinoxalinones as multifunctional aldose reductase inhibitors

(2019) Yunpeng Ji et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Anti-diabetic Properties of Calcium Channel Blockers: Inhibition Effects on Aldose Reductase Enzyme Activity

(2019) Cüneyt Türkeş et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Anti‐diabetic properties of dietary phenolic compounds: Inhibition effects on α‐Amylase, Aldose Reductase and α‐Glycosidase

(2019) Yeliz Demir et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Inhibition of Human Serum Paraoxonase-I with Antimycotic Drugs: In Vitro and In Silico Studies

(2019) Cüneyt Türkeş et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Gadolinium-based contrast agents: in vitro paraoxonase 1 inhibition, in silico studies

(2019) Şükrü Beydemir et al.   DRUG AND CHEMICAL TOXICOLOGY

A potential risk factor for paraoxonase 1: in silico and in‐vitro analysis of the biological activity of proton‐pump inhibitors

(2019) Cüneyt Türkeş   JOURNAL OF PHARMACY AND PHARMACOLOGY

The Influence of Some Nonsteroidal Anti-inflammatory Drugs on Metabolic Enzymes of Aldose Reductase, Sorbitol Dehydrogenase, and α-Glycosidase: a Perspective for Metabolic Disorders

(2019) Yeliz Demir et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Synthesis, biological evaluation and in silico studies of novel N-substituted phthalazine sulfonamide compounds as potent carbonic anhydrase and acetylcholinesterase inhibitors

(2019) Cüneyt Türkeş et al.   BIOORGANIC CHEMISTRY

The Binding Mechanisms and Inhibitory Effect of Intravenous Anesthetics on AChE In Vitro and In Vivo: Kinetic Analysis and Molecular Docking

(2019) Mesut Işık   NEUROCHEMICAL RESEARCH

In Vitro and In Silico Studies on the Toxic Effects of Antibacterial Drugs as Human Serum Paraoxonase 1 Inhibitor

(2019) Cüneyt Türkeş et al.   ChemistrySelect

Exploring antidiabetic potential of adamantyl-thiosemicarbazones via aldose reductase (ALR2) inhibition

(2019) Muhammad Tariq Shehzad et al.   BIOORGANIC CHEMISTRY

Benzenesulfonamide derivatives containing imine and amine groups: Inhibition on human paraoxonase and molecular docking studies

(2019) Mesut Işık et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Design, synthesis and molecular modelling studies of some pyrazole derivatives as carbonic anhydrase inhibitors

(2019) Yazgı Dizdaroglu et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

New Isoindole‐1,3‐dione Substituted Sulfonamides as Potent Inhibitors of Carbonic Anhydrase and Acetylcholinesterase: Design, Synthesis, and Biological Evaluation

(2019) Saliha Gündoğdu et al.   ChemistrySelect

Diarylmethanon, bromophenol and diarylmethane compounds: Discovery of potent aldose reductase, α-amylase and α-glycosidase inhibitors as new therapeutic approach in diabetes and functional hyperglycemia

(2018) Parham Taslimi et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Benzoxazinone-thiosemicarbazones as antidiabetic leads via aldose reductase inhibition: Synthesis, biological screening and molecular docking study

(2018) Muhammad Tariq Shehzad et al.   BIOORGANIC CHEMISTRY

Design, synthesis and biological evaluation of quinoline-indole derivatives as anti-tubulin agents targeting the colchicine binding site

(2018) Wenlong Li et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Phenolic compounds inhibit the aldose reductase enzyme from the sheep kidney

(2017) Yeliz Demir et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Synthesis and biological evaluation of histamine Schiff bases as carbonic anhydrase I, II, IV, VII, and IX activators

(2017) Suleyman Akocak et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Inhibition behaviours of some phenolic acids on rat kidney aldose reductase enzyme: an in vitro study

(2017) Zuhal Alim et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

In vitro inhibitory effects of palonosetron hydrochloride, bevacizumab and cyclophosphamide on purified paraoxonase-I (hPON1) from human serum

(2016) Cüneyt Türkeş et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

PEGylated Bis-Sulfonamide Carbonic Anhydrase Inhibitors Can Efficiently Control the Growth of Several Carbonic Anhydrase IX-Expressing Carcinomas

(2016) Suleyman Akocak et al.   JOURNAL OF MEDICINAL CHEMISTRY

Phase Transfer Catalysis with Quaternary Ammonium Type Gemini Surfactants: O-Alkylation of Isovanillin

(2016) Mesut Boz et al.   JOURNAL OF SURFACTANTS AND DETERGENTS

Synthesis, characterization, hypoglycemic and aldose reductase inhibition activity of arylsulfonylspiro[fluorene-9,5′-imidazolidine]-2′,4′-diones

(2015) Zafar Iqbal et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Ethylene bis-imidazoles are highly potent and selective activators for isozymes VA and VII of carbonic anhydrase, with a potential nootropic effect

(2014) Bogdan Draghici et al.   CHEMICAL COMMUNICATIONS

Structure–activity relationships studies of quinoxalinone derivatives as aldose reductase inhibitors

(2014) Saghir Hussain et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Human serum paraoxonase-1 (hPON1):in vitroinhibition effects of moxifloxacin hydrochloride, levofloxacin hemihidrate, cefepime hydrochloride, cefotaxime sodium and ceftizoxime sodium

(2014) Cüneyt Türkeş et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Effect of calcium channel blockers on paraoxonase-1 (PON1) activity and oxidative stress

(2014) Cüneyt Türkeş et al.   Pharmacological Reports

Inhibitor selectivity between aldo-keto reductase superfamily members AKR1B10 and AKR1B1: Role of Trp112 (Trp111)

(2013) Liping Zhang et al.   FEBS LETTERS

Protein and ligand preparation: parameters, protocols, and influence on virtual screening enrichments

(2013) G. Madhavi Sastry et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Synthesis and paroxonase activities of novel bromophenols

(2012) Yusuf Akbaba et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

New Approach for the Construction of the Coumarin Frame and Application in the Total Synthesis of Natural Products

(2011) Alberto Jerezano et al.   HELVETICA CHIMICA ACTA

Extraction and identification of three major aldose reductase inhibitors from Artemisia montana

(2010) Hyun Ah Jung et al.   FOOD AND CHEMICAL TOXICOLOGY

A Diverse Series of Substituted Benzenesulfonamides as Aldose Reductase Inhibitors with Antioxidant Activity: Design, Synthesis, and in Vitro Activity

(2010) Polyxeni Alexiou et al.   JOURNAL OF MEDICINAL CHEMISTRY

Inhibition of aldose reductase by dietary antioxidant curcumin: Mechanism of inhibition, specificity and significance

(2009) P. Muthenna et al.   FEBS LETTERS

Identifying and Characterizing Binding Sites and Assessing Druggability

(2009) Thomas A. Halgren   Journal of Chemical Information and Modeling

Organic chemosensors with crown-ether groups (review)

(2008) A. V. Tsukanov et al.   Chemistry of Heterocyclic Compounds