Molecular docking and inhibition studies of vulpinic, carnosic and usnic acids on polyol pathway enzymes

Synthesis of N ‐alkylated pyrazolo[3,4‐ d ]pyrimidine analogs and evaluation of acetylcholinesterase and carbonic anhydrase inhibition properties

(2021) Busra O. Aydin et al.   ARCHIV DER PHARMAZIE

Elucidating the Interaction of Human Ferritin with Quercetin and Naringenin: Implication of Natural Products in Neurodegenerative Diseases: Molecular Docking and Dynamics Simulation Insight

(2021) Anas Shamsi et al.   ACS Omega

Novel inhibitors with sulfamethazine backbone: synthesis and biological study of multi-target cholinesterases and α-glucosidase inhibitors

(2021) Cüneyt Türkeş et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Insight into the In Vitro Antiglycation and In Vivo Antidiabetic Effects of Thiamine: Implications of Vitamin B1 in Controlling Diabetes

(2021) K. M. Abdullah et al.   ACS Omega

Design, synthesis, characterization, in vitro and in silico evaluation of novel imidazo[2,1-b][1,3,4]thiadiazoles as highly potent acetylcholinesterase and non-classical carbonic anhydrase inhibitors

(2021) Sercan Askin et al.   BIOORGANIC CHEMISTRY

Identification of a new class of potent aldose reductase inhibitors: Design, microwave-assisted synthesis, in vitro and in silico evaluation of 2-pyrazolines

(2021) Belgin Sever et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Transition‐Metal Complexes of Bidentate Schiff‐Base Ligands: In Vitro and In Silico Evaluation as Non‐Classical Carbonic Anhydrase and Potential Acetylcholinesterase Inhibitors

(2021) Ümit Yaşar et al.   ChemistrySelect

Molecular Docking Studies and Inhibition Properties of Some Antineoplastic Agents against Paraoxonase-I

(2020) Yeliz Demir et al.   Anti-Cancer Agents in Medicinal Chemistry

Calcium Channel Blockers: Molecular Docking and Inhibition Studies on Carbonic Anhydrase I and II Isoenzymes

(2020) Cüneyt Türkeş et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Sulfonamides incorporating ketene N,S -acetal bioisosteres as potent carbonic anhydrase and acetylcholinesterase inhibitors

(2020) Qëndresa Istrefi et al.   ARCHIV DER PHARMAZIE

Antioxidants and antioxidant methods: an updated overview

(2020) İlhami Gulcin   ARCHIVES OF TOXICOLOGY

Naphthoquinones, benzoquinones, and anthraquinones: Molecular docking, ADME and inhibition studies on human serum paraoxonase-1 associated with cardiovascular diseases

(2020) Yeliz Demir   DRUG DEVELOPMENT RESEARCH

Ellagic Acid Controls Cell Proliferation and Induces Apoptosis in Breast Cancer Cells via Inhibition of Cyclin-Dependent Kinase 6

(2020) Mohd Yousuf et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Some sulfonamides as aldose reductase inhibitors: therapeutic approach in diabetes

(2020) Yeliz Demir et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Synthesis, characterization, biological evaluation, and in silico studies of novel 1,3‐diaryltriazene‐substituted sulfathiazole derivatives

(2020) Mesut Işık et al.   ARCHIV DER PHARMAZIE

Determination of the inhibition profiles of pyrazolyl–thiazole derivatives against aldose reductase and α‐glycosidase and molecular docking studies

(2020) Yeliz Demir et al.   ARCHIV DER PHARMAZIE

Synthesis, characterization, inhibition effects, and molecular docking studies as acetylcholinesterase, α-glycosidase, and carbonic anhydrase inhibitors of novel benzenesulfonamides incorporating 1,3,5-triazine structural motifs

(2020) Nebih Lolak et al.   BIOORGANIC CHEMISTRY

Rosmarinic Acid Exhibits Anticancer Effects via MARK4 Inhibition

(2020) Saleha Anwar et al.   Scientific Reports

Discovery of Hordenine as a Potential Inhibitor of Pyruvate Dehydrogenase Kinase 3: Implication in Lung Cancer Therapy

(2020) Saleha Anwar et al.   Biomedicines

Design, synthesis, in vitro and in silico investigation of aldose reductase inhibitory effects of new thiazole-based compounds

(2020) Belgin Sever et al.   BIOORGANIC CHEMISTRY

Rosmarinic acid restrains protein glycation and aggregation in human serum albumin: Multi spectroscopic and microscopic insight - Possible Therapeutics Targeting Diseases

(2020) Anas Shamsi et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

An extensive research on aldose reductase inhibitory effects of new 4H-1,2,4-triazole derivatives

(2020) Belgin Sever et al.   JOURNAL OF MOLECULAR STRUCTURE

Inhibitory effects of usnic and carnosic acid on some metabolic enzymes: an in vitro study

(2019) Hamid Ceylan et al.   PROTEIN AND PEPTIDE LETTERS

Investigation of Potential Paraoxonase-I Inhibitors by Kinetic and Molecular Docking Studies: Chemotherapeutic Drugs

(2019) Cüneyt Türkeş   PROTEIN AND PEPTIDE LETTERS

The antidiabetic and anticholinergic effects of chrysin on cyclophosphamide-induced multiple organ toxicity in rats: Pharmacological evaluation of some metabolic enzyme activities

(2019) Parham Taslimi et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Carnosic Acid Inhibits CXCR3 Ligands Production in IL-27-Stimulated Human Oral Epithelial Cells

(2019) Ikuko Hosokawa et al.   INFLAMMATION

Vulpinic acid, a lichen metabolite, emerges as a potential drug candidate in the therapy of oxidative stress–related diseases, such as atherosclerosis

(2019) E Sahin et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Anti-diabetic Properties of Calcium Channel Blockers: Inhibition Effects on Aldose Reductase Enzyme Activity

(2019) Cüneyt Türkeş et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Anti‐diabetic properties of dietary phenolic compounds: Inhibition effects on α‐Amylase, Aldose Reductase and α‐Glycosidase

(2019) Yeliz Demir et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Diabetic Nephropathy Following Posttransplant Diabetes Mellitus

(2019) Ayman Maher Nagib et al.   Experimental and Clinical Transplantation

Inhibition of Human Serum Paraoxonase-I with Antimycotic Drugs: In Vitro and In Silico Studies

(2019) Cüneyt Türkeş et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Gadolinium-based contrast agents: in vitro paraoxonase 1 inhibition, in silico studies

(2019) Şükrü Beydemir et al.   DRUG AND CHEMICAL TOXICOLOGY

The behaviour of some antihypertension drugs on human serum paraoxonase‐1: an important protector enzyme against atherosclerosis

(2019) Yeliz Demir   JOURNAL OF PHARMACY AND PHARMACOLOGY

A potential risk factor for paraoxonase 1: in silico and in‐vitro analysis of the biological activity of proton‐pump inhibitors

(2019) Cüneyt Türkeş   JOURNAL OF PHARMACY AND PHARMACOLOGY

The Influence of Some Nonsteroidal Anti-inflammatory Drugs on Metabolic Enzymes of Aldose Reductase, Sorbitol Dehydrogenase, and α-Glycosidase: a Perspective for Metabolic Disorders

(2019) Yeliz Demir et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Synthesis, biological evaluation and in silico studies of novel N-substituted phthalazine sulfonamide compounds as potent carbonic anhydrase and acetylcholinesterase inhibitors

(2019) Cüneyt Türkeş et al.   BIOORGANIC CHEMISTRY

Inhibition effects of quinones on aldose reductase: Antidiabetic properties

(2019) Yeliz Demir et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

The effects of zingerone against vancomycin‐induced lung, liver, kidney and testis toxicity in rats: The behavior of some metabolic enzymes

(2019) Cüneyt Çağlayan et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

In Vitro and In Silico Studies on the Toxic Effects of Antibacterial Drugs as Human Serum Paraoxonase 1 Inhibitor

(2019) Cüneyt Türkeş et al.   ChemistrySelect

Novel 2-aminopyridine liganded Pd(II) N-heterocyclic carbene complexes: Synthesis, characterization, crystal structure and bioactivity properties

(2019) Fatoş Erdemir et al.   BIOORGANIC CHEMISTRY

Benzenesulfonamide derivatives containing imine and amine groups: Inhibition on human paraoxonase and molecular docking studies

(2019) Mesut Işık et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

The Signaling of Cellular Senescence in Diabetic Nephropathy

(2019) Yabing Xiong et al.   Oxidative Medicine and Cellular Longevity

Purification of Polyphenol Oxidase from Potato and Investigation of the Inhibitory Effects of Phenolic Acids on Enzyme Activity

(2019) Songül Bayrak et al.   PROTEIN AND PEPTIDE LETTERS

Differential effects of selective serotonin reuptake inhibitors on paraoxonase-1 enzyme activity: An in vitro study

(2019) Yeliz Demir et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

New Isoindole‐1,3‐dione Substituted Sulfonamides as Potent Inhibitors of Carbonic Anhydrase and Acetylcholinesterase: Design, Synthesis, and Biological Evaluation

(2019) Saliha Gündoğdu et al.   ChemistrySelect

The aldose reductase inhibitor epalrestat exerts nephritic protection on diabetic nephropathy in db/db mice through metabolic modulation

(2018) Jun He et al.   ACTA PHARMACOLOGICA SINICA

Lichen acids may be used as a potential drug for cancer therapy; by inhibiting mitochondrial thioredoxin reductase purified from rat lung

(2018) Ilknur Ozgencli et al.   Anti-Cancer Agents in Medicinal Chemistry

Evaluation of chalcones as inhibitors of glutathione S-transferase

(2018) Muhammet Serhat Özaslan et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Protective effect of carnosic acid and its semisynthetic derivatives against H 2 O 2 -induced neurotoxicity

(2018) Xinxin Liang et al.   Phytochemistry Letters

Bioavailability of resveratrol: Possibilities for enhancement

(2018) Konrad de Vries et al.   Journal of Herbal Medicine

Antidiabetic potential: In vitro inhibition effects of bromophenol and diarylmethanones derivatives on metabolic enzymes

(2018) Yeliz Demir et al.   ARCHIV DER PHARMAZIE

The effects of hesperidin on sodium arsenite-induced different organ toxicity in rats on metabolic enzymes as antidiabetic and anticholinergics potentials: A biochemical approach

(2018) Cuneyt Caglayan et al.   JOURNAL OF FOOD BIOCHEMISTRY

The therapeutic potential of curcumin: A review of clinical trials

(2018) Bahare Salehi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Inhibition of glycation and aldose reductase activity using dietary flavonoids: A lens organ culture studies

(2017) Kapil K. Patil et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Mechanism of capsaicin inhibition of aldose reductase activity

(2017) Zuhal Alim et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Phenolic compounds inhibit the aldose reductase enzyme from the sheep kidney

(2017) Yeliz Demir et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Inhibition behaviours of some phenolic acids on rat kidney aldose reductase enzyme: an in vitro study

(2017) Zuhal Alim et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

The interactions of cephalosporins on polyol pathway enzymes from sheep kidney

(2017) Bülent Şengül et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

In vitro inhibitory effects of palonosetron hydrochloride, bevacizumab and cyclophosphamide on purified paraoxonase-I (hPON1) from human serum

(2016) Cüneyt Türkeş et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Therapeutic Potential of Essential Oils Focusing on Diterpenes

(2016) Md. Torequl Islam et al.   PHYTOTHERAPY RESEARCH

Review of the biological properties and toxicity of usnic acid

(2015) A. A. S. Araújo et al.   NATURAL PRODUCT RESEARCH

Carnosic acid stimulates glucose uptake in skeletal muscle cells via a PME-1/PP2A/PKB signalling axis

(2014) Christopher Lipina et al.   CELLULAR SIGNALLING

Human serum paraoxonase-1 (hPON1):in vitroinhibition effects of moxifloxacin hydrochloride, levofloxacin hemihidrate, cefepime hydrochloride, cefotaxime sodium and ceftizoxime sodium

(2014) Cüneyt Türkeş et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Effect of calcium channel blockers on paraoxonase-1 (PON1) activity and oxidative stress

(2014) Cüneyt Türkeş et al.   Pharmacological Reports

Inhibitor selectivity between aldo-keto reductase superfamily members AKR1B10 and AKR1B1: Role of Trp112 (Trp111)

(2013) Liping Zhang et al.   FEBS LETTERS

Synthesis and paroxonase activities of novel bromophenols

(2012) Yusuf Akbaba et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Separation of antigens and antibodies by immunoaffinity chromatography

(2012) Shuai Sheng et al.   PHARMACEUTICAL BIOLOGY

Antiproliferation effect of Rosemary (Rosmarinus officinalis) on human ovarian cancer cells in vitro

(2012) Joseph Tai et al.   PHYTOMEDICINE

Effects of some anti-neoplastic drugs on sheep liver sorbitol dehydrogenase

(2012) Zuhal Alım et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Antioxidant activity of food constituents: an overview

(2011) İlhami Gülçin   ARCHIVES OF TOXICOLOGY