Hepatorenal protective efficacy of flavonoids from Ocimum basilicum extract in diabetic albino rats: A focus on hypoglycemic, antioxidant, anti-inflammatory and anti-apoptotic activities

Neuroprotective effects of protocatechuic acid on sodium arsenate induced toxicity in mice: Role of oxidative stress, inflammation, and apoptosis

(2021) Zhaoxia Li et al.   CHEMICO-BIOLOGICAL INTERACTIONS

The ameliorative role of Physalis pubescens L. against neurological impairment associated with streptozotocin induced diabetes in rats

(2021) Atef Abdel-Moneem Ali et al.   METABOLIC BRAIN DISEASE

Gamma-aminobutyric acid attenuates insulin resistance in type 2 diabetic patients and reduces the risk of insulin resistance in their offspring

(2021) Hossein Rezazadeh et al.   BIOMEDICINE & PHARMACOTHERAPY

Protective Effect of Hydroxysafflor Yellow A on Nephropathy by Attenuating Oxidative Stress and Inhibiting Apoptosis in Induced Type 2 Diabetes in Rat

(2020) Maosheng Lee et al.   Oxidative Medicine and Cellular Longevity

Physiological and histopathological study on the influence ofOcimum basilicum leaves extract on thioacetamide-induced nephrotoxicity in male rats

(2020) Mohammed Y. Alomar   SAUDI JOURNAL OF BIOLOGICAL SCIENCES

Neuromodulatory effects of green coffee bean extract against brain damage in male albino rats with experimentally induced diabetes

(2020) Ashraf Al-Brakati et al.   METABOLIC BRAIN DISEASE

Investigation of antioxidant and anti-inflammatory activities as well as the renal protective potential of green coffee extract in high fat-diet/streptozotocin-induced diabetes in male albino rats

(2020) Ohoud D. AlAmri et al.   Journal of Functional Foods

Comparative immuno-modulatory effects of basil and sesame seed oils against diazinon-induced toxicity in rats; a focus on TNF-α immunolocalization

(2020) Sameh Mohamed Farouk et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Ferulic acid influences Nrf2 activation to restore testicular tissue from cadmium‐induced oxidative challenge, inflammation, and apoptosis in rats

(2020) Rami B. Kassab et al.   JOURNAL OF FOOD BIOCHEMISTRY

Anti-inflammatory activities of puerarin in high-fat diet-fed rats with streptozotocin-induced gestational diabetes mellitus

(2020) Wenting Xu et al.   MOLECULAR BIOLOGY REPORTS

Ocimum basilicum (Basil) Modulates Apoptosis and Neurogenesis in Olfactory Pulp of Mice Exposed to Chronic Unpredictable Mild Stress

(2020) Nasra N. Ayuob et al.   Frontiers in Psychiatry

Chlorogenic acid abates male reproductive dysfunction in arsenic-exposed mice via attenuation of testicular oxido-inflammatory stress and apoptotic responses

(2020) Manal F. El-Khadragy et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Synergistic Effect of Omega-3 Fatty Acids and Oral-Hypoglycemic Drug on Lipid Normalization through Modulation of Hepatic Gene Expression in High Fat Diet with Low Streptozotocin-Induced Diabetic Rats

(2020) Suresh Khadke et al.   Nutrients

Chitosan-stabilized selenium nanoparticles alleviate cardio-hepatic damage in type 2 diabetes mellitus model via regulation of caspase, Bax/Bcl-2, and Fas/FasL-pathway

(2020) Amany Abdel-Rahman Mohamed et al.   GENE

Antidiabetic effect of a flavonoid-rich extract from Sophora alopecuroides L. in HFD- and STZ- induced diabetic mice through PKC/GLUT4 pathway and regulating PPARα and PPARγ expression

(2020) Yibing Lv et al.   JOURNAL OF ETHNOPHARMACOLOGY

Rosa rugosa flavonoids exhibited PPARα agonist-like effects on genetic severe hypertriglyceridemia of mice

(2019) Asiya Baiyisaiti et al.   JOURNAL OF ETHNOPHARMACOLOGY

Ocimum kilimandscharicum L. restores ovarian functions in letrozole - induced Polycystic Ovary Syndrome (PCOS) in rats: Comparison with metformin

(2019) Nada Khaled et al.   LIFE SCIENCES

Phytochemical profile and protective effect of Ocimum basilicum aqueous extract in doxorubicin/irradiation‐induced testicular injury

(2019) Rasha Y. M. Ibrahim et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Antagonistic Efficacy of Luteolin against Lead Acetate Exposure-Associated with Hepatotoxicity is Mediated via Antioxidant, Anti-Inflammatory, and Anti-Apoptotic Activities

(2019) Wafa A. AL-Megrin et al.   Antioxidants

Crocin potentiates antioxidant defense system and improves oxidative damage in liver tissue in diabetic rats

(2018) Habib Yaribeygi et al.   BIOMEDICINE & PHARMACOTHERAPY

Polyphenol-rich extract of Ocimum gratissimum leaves ameliorates colitis via attenuating colonic mucosa injury and regulating pro-inflammatory cytokines production and oxidative stress

(2018) Quadri K. Alabi et al.   BIOMEDICINE & PHARMACOTHERAPY

Protective role of Ocimum basilicum L. (Basil) against aspirin-induced gastric ulcer in mice: Impact on oxidative stress, inflammation, motor deficits and anxiety-like behavior

(2018) Eman Abd El-Ghffar et al.   Food & Function

Zingerone (4-(4-hydroxy-3-methylphenyl)butan-2-one) ameliorates renal function via controlling oxidative burst and inflammation in experimental diabetic nephropathy

(2018) Muneeb U. Rehman et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Assessment of anti-diabetic activity of peanut shell polyphenol extracts

(2018) Xiao-meng Sun et al.   Journal of Zhejiang University-SCIENCE B

Anti-inflammatory activity of the essential oil obtained from Ocimum basilicum complexed with β-cyclodextrin (β-CD) in mice

(2017) Lindaiane Bezerra Rodrigues et al.   FOOD AND CHEMICAL TOXICOLOGY

Phyllanthus niruri leaves aqueous extract improves kidney functions, ameliorates kidney oxidative stress, inflammation, fibrosis and apoptosis and enhances kidney cell proliferation in adult male rats with diabetes mellitus

(2017) Nelli Giribabu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Phenolic Substances from Ocimum Species Enhance Glucose-Stimulated Insulin Secretion and Modulate the Expression of Key Insulin Regulatory Genes in Mice Pancreatic Islets

(2017) Livia Marques Casanova et al.   JOURNAL OF NATURAL PRODUCTS

Anti-Diabetic Effects of Phenolic Extract from Rambutan Peels (Nephelium lappaceum) in High-Fat Diet and Streptozotocin-Induced Diabetic Mice

(2017) et al.   Nutrients

In-vivo study for anti-hyperglycemic potential of aqueous extract of Basil seeds ( Ocimum basilicum Linn) and its influence on biochemical parameters, serum electrolytes and haematological indices

(2016) Sachin Chaudhary et al.   BIOMEDICINE & PHARMACOTHERAPY

Anti-inflammatory and antiedematogenic activity of the Ocimum basilicum essential oil and its main compound estragole: In vivo mouse models

(2016) Lindaiane Bezerra Rodrigues et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Alterations in blood pressure, antioxidant status and caspase 8 expression in cobalt chloride-induced cardio-renal dysfunction are reversed by Ocimum gratissimum and gallic acid in Wistar rats

(2016) A.S. Akinrinde et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Effects of crocin and voluntary exercise, alone or combined, on heart VEGF-A and HOMA-IR of HFD/STZ induced type 2 diabetic rats

(2016) V. Ghorbanzadeh et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

Hepatocyte Growth Factor Mediates the Antifibrogenic Action of Ocimum bacilicum Essential Oil against CCl4-Induced Liver Fibrosis in Rats

(2015) Hanan Ogaly et al.   MOLECULES

Evaluation of Antioxidant and Antimicrobial Activities and Phenolic Profile for Hyssopus officinalis, Ocimum basilicum and Teucrium chamaedrys

(2014) Laurian Vlase et al.   MOLECULES

Consumption of Ocimum sanctum L. and Citrus paradisi infusions modulates lipid metabolism and insulin resistance in obese rats

(2014) Claudia Gamboa-Gómez et al.   Food & Function

The Neuroprotective Effects of Purslane (Portulaca oleracea) on Rotenone- Induced Biochemical Changes and Apoptosis in Brain of Rat

(2013) Ahmed Abdel Moneim   CNS & Neurological Disorders-Drug Targets

Hypoglycemic effect of basil (Ocimum basilicum) aqueous extract is mediated through inhibition of α-glucosidase and α-amylase activities

(2011) HA El-Beshbishy et al.   TOXICOLOGY AND INDUSTRIAL HEALTH