A Src-H3 acetylation signaling axis integrates macrophage mechanosensation with inflammatory response

YAP-mediated mechanotransduction tunes the macrophage inflammatory response

(2020) Vijaykumar S. Meli et al.   Science Advances

Biophysical regulation of macrophages in health and disease

(2019) Vijaykumar S. Meli et al.   JOURNAL OF LEUKOCYTE BIOLOGY

BRD4 directs hematopoietic stem cell development and modulates macrophage inflammatory responses

(2019) Anup Dey et al.   EMBO JOURNAL

Mechanosensation of cyclical force by PIEZO1 is essential for innate immunity

(2019) Angel G. Solis et al.   NATURE

WDR5 modulates cell motility and morphology and controls nuclear changes induced by a 3D environment

(2018) Pengbo Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spatial confinement downsizes the inflammatory response of macrophages

(2018) Nikhil Jain et al.   NATURE MATERIALS

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

The macrophage cytoskeleton acts as a contact sensor upon interaction with Entamoeba histolytica to trigger IL-1β secretion

(2017) Joëlle St-Pierre et al.   PLoS Pathogens

The histone acetyltransferase p300 inhibitor C646 reduces pro-inflammatory gene expression and inhibits histone deacetylases

(2016) Thea van den Bosch et al.   BIOCHEMICAL PHARMACOLOGY

Effect of M1–M2 Polarization on the Motility and Traction Stresses of Primary Human Macrophages

(2016) Laurel E. Hind et al.   Cellular and Molecular Bioengineering

Integrin CD11b attenuates colitis by strengthening Src-Akt pathway to polarize anti-inflammatory IL-10 expression

(2016) Xiang Hu et al.   Scientific Reports

Topographical modulation of macrophage phenotype by shrink-film multi-scale wrinkles

(2016) Tingting Wang et al.   Biomaterials Science

Substrate engagement of integrins α5β1 and αvβ3 is necessary, but not sufficient, for high directional persistence in migration on fibronectin

(2016) Dimitris Missirlis et al.   Scientific Reports

Micro- and Nanopatterned Topographical Cues for Regulating Macrophage Cell Shape and Phenotype

(2015) Thuy U. Luu et al.   ACS Applied Materials & Interfaces

Curcumin Modulates Macrophage Polarization Through the Inhibition of the Toll-Like Receptor 4 Expression and its Signaling Pathways

(2015) Yaoyao Zhou et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Macrophage motility is driven by frontal-towing with a force magnitude dependent on substrate stiffness

(2015) Laurel E. Hind et al.   Integrative Biology

Transcription factor binding dynamics during human ES cell differentiation

(2015) Alexander M. Tsankov et al.   NATURE

Kinetics of sickle cell biorheology and implications for painful vasoocclusive crisis

(2015) E Du et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PARP-1 Mediates LPS-Induced HMGB1 Release by Macrophages through Regulation of HMGB1 Acetylation

(2014) Zhiyong Yang et al.   JOURNAL OF IMMUNOLOGY

The integrin adhesome: from genes and proteins to human disease

(2014) Sabina E. Winograd-Katz et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Actin polymerization as a key innate immune effector mechanism to controlSalmonellainfection

(2014) Si Ming Man et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cadherin adhesome at a glance

(2013) R. Zaidel-Bar   JOURNAL OF CELL SCIENCE

BET Protein Function Is Required for Inflammation: Brd2 Genetic Disruption and BET Inhibitor JQ1 Impair Mouse Macrophage Inflammatory Responses

(2013) A. C. Belkina et al.   JOURNAL OF IMMUNOLOGY

Biophysical regulation of epigenetic state and cell reprogramming

(2013) Timothy L. Downing et al.   NATURE MATERIALS

Modulation of macrophage phenotype by cell shape

(2013) F. Y. McWhorter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell geometric constraints induce modular gene-expression patterns via redistribution of HDAC3 regulated by actomyosin contractility

(2013) N. Jain et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of filopodia in the recognition of nanotopographies

(2013) Jörg Albuschies et al.   Scientific Reports

The Role of Src Kinase in Macrophage-Mediated Inflammatory Responses

(2012) Se Eun Byeon et al.   MEDIATORS OF INFLAMMATION

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Spatial organization of the extracellular matrix regulates cell-cell junction positioning

(2012) Q. Tseng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetic regulation of macrophage polarization and function

(2012) Lionel B. Ivashkiv   TRENDS IN IMMUNOLOGY

Spatial coordination between cell and nuclear shape within micropatterned endothelial cells

(2012) Marie Versaevel et al.   Nature Communications

Biophysical Regulation of Histone Acetylation in Mesenchymal Stem Cells

(2011) Yuan Li et al.   BIOPHYSICAL JOURNAL

The regulation of traction force in relation to cell shape and focal adhesions

(2010) Andrew D. Rape et al.   BIOMATERIALS

Identification and Characterization of Enhancers Controlling the Inflammatory Gene Expression Program in Macrophages

(2010) Serena Ghisletti et al.   IMMUNITY

Metabolism and cell shape in cancer: A fractal analysis

(2010) Fabrizio D’Anselmi et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The epigenetic mechanism of mechanically induced osteogenic differentiation

(2010) Emily J. Arnsdorf et al.   JOURNAL OF BIOMECHANICS

Suppression of inflammation by a synthetic histone mimic

(2010) Edwige Nicodeme et al.   NATURE

Geometric cues for directing the differentiation of mesenchymal stem cells

(2010) K. A. Kilian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Visualizing the Effect of Microenvironment on the Spatiotemporal RhoA and Src Activities in Living Cells by FRET

(2009) Tae-Jin Kim et al.   Small

Heterogeneity of Human Macrophages in Culture and in Atherosclerotic Plaques

(2008) Stephen W. Waldo et al.   AMERICAN JOURNAL OF PATHOLOGY

Rapid signal transduction in living cells is a unique feature of mechanotransduction

(2008) S. Na et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA