Mechanosensation of cyclical force by PIEZO1 is essential for innate immunity

Distinct modes of mitochondrial metabolism uncouple T cell differentiation and function

(2019) Will Bailis et al.   NATURE

The mechanosensitive ion channel Piezo2 mediates sensitivity to mechanical pain in mice

(2018) Swetha E. Murthy et al.   Science Translational Medicine

Mechanical stretch triggers rapid epithelial cell division through Piezo1

(2017) S. A. Gudipaty et al.   NATURE

Inactivation of Mechanically Activated Piezo1 Ion Channels Is Determined by the C-Terminal Extracellular Domain and the Inner Pore Helix

(2017) Jason Wu et al.   Cell Reports

Endothelial cation channel PIEZO1 controls blood pressure by mediating flow-induced ATP release

(2016) ShengPeng Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

GPR91 senses extracellular succinate released from inflammatory macrophages and exacerbates rheumatoid arthritis

(2016) Amanda Littlewood-Evans et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mechanism and Regulation of NLRP3 Inflammasome Activation

(2016) Yuan He et al.   TRENDS IN BIOCHEMICAL SCIENCES

Macrophages monitor tissue osmolarity and induce inflammatory response through NLRP3 and NLRC4 inflammasome activation

(2015) W. K. Eddie Ip et al.   Nature Communications

Physical and mechanical regulation of macrophage phenotype and function

(2014) Frances Y. McWhorter et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

HIF Transcription Factors, Inflammation, and Immunity

(2014) Asis Palazon et al.   IMMUNITY

Functional Role for Piezo1 in Stretch-evoked Ca2+Influx and ATP Release in Urothelial Cell Cultures

(2014) Tatsuya Miyamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comparative analysis of the efficiency and specificity of myeloid-Cre deleting strains using ROSA-EYFP reporter mice

(2014) Clare L. Abram et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Piezo1 integration of vascular architecture with physiological force

(2014) Jing Li et al.   NATURE

Gastrointestinal motility disorders in inflammatory bowel diseases

(2014) Gabrio Bassotti   WORLD JOURNAL OF GASTROENTEROLOGY

Extracellular Acidosis Is a Novel Danger Signal Alerting Innate Immunity via the NLRP3 Inflammasome

(2013) Kristiina Rajamäki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

(2013) G. M. Tannahill et al.   NATURE

Endothelin-1 induces hypoxia inducible factor 1α expression in pulmonary artery smooth muscle cells

(2012) Manxiang Li et al.   FEBS LETTERS

Molecular mechanisms of mechanotransduction in mammalian sensory neurons

(2011) Patrick Delmas et al.   NATURE REVIEWS NEUROSCIENCE

Bleomycin induced lung fibrosis increases work of breathing in the mouse

(2011) Jonathan E. Phillips et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Design of a Cyclic Pressure Bioreactor for the Ex Vivo Study of Aortic Heart Valves

(2011) Kimberly J. Schipke et al.   Jove-Journal of Visualized Experiments

Endothelin-1 gene regulation

(2010) Lisa R. Stow et al.   FASEB JOURNAL

Macrophage motility requires distinct α5β1/FAK and α4β1/paxillin signaling events

(2010) Michelle Y. Abshire et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

(2010) B. Coste et al.   SCIENCE

Hypoxia activates the cyclooxygenase-2–prostaglandin E synthase axis

(2009) James J. Lee et al.   CARCINOGENESIS

Pattern recognition receptors and control of adaptive immunity

(2008) Noah W. Palm et al.   IMMUNOLOGICAL REVIEWS

Focal Adhesion Kinase Is Important for Fluid Shear Stress–Induced Mechanotransduction in Osteoblasts

(2008) Suzanne RL Young et al.   JOURNAL OF BONE AND MINERAL RESEARCH