The Australian Genetics of Depression Study: New Risk Loci and Dissecting Heterogeneity Between Subtypes

Genetic correlates of socio-economic status influence the pattern of shared heritability across mental health traits

(2021) Andries T. Marees et al.   Nature Human Behaviour

Polygenic Liability and Recurrence of Depression in Patients With First-Onset Depression Treated in Hospital-Based Settings

(2021) Katherine L. Musliner et al.   JAMA Psychiatry

Bi-ancestral depression GWAS in the Million Veteran Program and meta-analysis in >1.2 million individuals highlight new therapeutic directions

(2021) Daniel F. Levey et al.   NATURE NEUROSCIENCE

Polygenic Risk Scores Derived From Varying Definitions of Depression and Risk of Depression

(2021) Brittany L. Mitchell et al.   JAMA Psychiatry

Minimal phenotyping yields genome-wide association signals of low specificity for major depression

(2020) Na Cai et al.   NATURE GENETICS

Reviewing the genetics of heterogeneity in depression: operationalizations, manifestations and etiologies

(2020) Na Cai et al.   HUMAN MOLECULAR GENETICS

Depression with atypical neurovegetative symptoms shares genetic predisposition with immuno-metabolic traits and alcohol consumption

(2020) Isabella Badini et al.   PSYCHOLOGICAL MEDICINE

Could Polygenic Risk Scores Be Useful in Psychiatry?

(2020) Graham K. Murray et al.   JAMA Psychiatry

Multivariate genome-wide analysis of education, socioeconomic status and brain phenome

(2020) Frank R. Wendt et al.   Nature Human Behaviour

The Tenets of Teneurin: Conserved Mechanisms Regulate Diverse Developmental Processes in the Drosophila Nervous System

(2019) Alison T. DePew et al.   Frontiers in Neuroscience

Association of Polygenic Liabilities for Major Depression, Bipolar Disorder, and Schizophrenia With Risk for Depression in the Danish Population

(2019) Katherine L. Musliner et al.   JAMA Psychiatry

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions

(2019) David M. Howard et al.   NATURE NEUROSCIENCE

Polygenic Risk: Predicting Depression Outcomes in Clinical and Epidemiological Cohorts of Youths

(2019) Thorhildur Halldorsdottir et al.   AMERICAN JOURNAL OF PSYCHIATRY

Genome-wide association study identifies 30 loci associated with bipolar disorder

(2019) Eli A. Stahl et al.   NATURE GENETICS

A major role for common genetic variation in anxiety disorders

(2019) Kirstin L. Purves et al.   MOLECULAR PSYCHIATRY

A resource-efficient tool for mixed model association analysis of large-scale data

(2019) Longda Jiang et al.   NATURE GENETICS

Improved polygenic prediction by Bayesian multiple regression on summary statistics

(2019) Luke R. Lloyd-Jones et al.   Nature Communications

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

(2018) Naomi R. Wray et al.   NATURE GENETICS

Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection

(2018) Antonio F. Pardiñas et al.   NATURE GENETICS

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

(2018) James J. Lee et al.   NATURE GENETICS

Neurodevelopmental theory of depression

(2018) Piotr Gałecki et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Estimation of complex effect-size distributions using summary-level statistics from genome-wide association studies across 32 complex traits

(2018) Yan Zhang et al.   NATURE GENETICS

Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies

(2018) Wei Zhou et al.   NATURE GENETICS

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

(2018) Ditte Demontis et al.   NATURE GENETICS

Characterizing Developmental Trajectories and the Role of Neuropsychiatric Genetic Risk Variants in Early-Onset Depression

(2018) Frances Rice et al.   JAMA Psychiatry

Genetic Association of Major Depression With Atypical Features and Obesity-Related Immunometabolic Dysregulations

(2017) Yuri Milaneschi et al.   JAMA Psychiatry

RBFOX1, encoding a splicing regulator, is a candidate gene for aggressive behavior

(2017) Noèlia Fernàndez-Castillo et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis

(2016) Jie Zheng et al.   BIOINFORMATICS

Polygenic dissection of major depression clinical heterogeneity

(2015) Y Milaneschi et al.   MOLECULAR PSYCHIATRY

Sparse whole-genome sequencing identifies two loci for major depressive disorder

(2015) Na Cai et al.   NATURE

Genetic studies of body mass index yield new insights for obesity biology

(2015) Adam E. Locke et al.   NATURE

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

(2015) Brendan K Bulik-Sullivan et al.   NATURE GENETICS

Generalised Anxiety Disorder – A Twin Study of Genetic Architecture, Genome-Wide Association and Differential Gene Expression

(2015) Matthew N. Davies et al.   PLoS One

Seasonality Shows Evidence for Polygenic Architecture and Genetic Correlation With Schizophrenia and Bipolar Disorder

(2014) Enda M. Byrne et al.   JOURNAL OF CLINICAL PSYCHIATRY

Intragenic deletion of RBFOX1 associated with neurodevelopmental/neuropsychiatric disorders and possibly other clinical presentations

(2013) Wei-Wei Zhao   Molecular Cytogenetics

RBFOX1 regulates both splicing and transcriptional networks in human neuronal development

(2012) Brent L. Fogel et al.   HUMAN MOLECULAR GENETICS

Cohort profile: The QSkin Sun and Health Study

(2012) C. M. Olsen et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Meta-review of depressive subtyping models

(2011) Baumeister Harald et al.   JOURNAL OF AFFECTIVE DISORDERS

The splicing regulator Rbfox1 (A2BP1) controls neuronal excitation in the mammalian brain

(2011) Lauren T Gehman et al.   NATURE GENETICS

GCTA: A Tool for Genome-wide Complex Trait Analysis

(2010) Jian Yang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The Netherlands Study of Depression and Anxiety (NESDA): rationale, objectives and methods

(2008) Brenda W.J.H. Penninx et al.   INTERNATIONAL JOURNAL OF METHODS IN PSYCHIATRIC RESEARCH

Neuregulin 1 in neural development, synaptic plasticity and schizophrenia

(2008) Lin Mei et al.   NATURE REVIEWS NEUROSCIENCE