Neurotoxicity of oligomers of phosphorylated Tau protein carrying tauopathy-associated mutation is inhibited by prion protein

The Quest for Cellular Prion Protein Functions in the Aged and Neurodegenerating Brain

(2020) Rosalina Gavín et al.   Cells

The uptake of tau amyloid fibrils is facilitated by the cellular prion protein and hampers prion propagation in cultured cells

(2020) Elena De Cecco et al.   JOURNAL OF NEUROCHEMISTRY

Tau Protein as a New Regulator of Cellular Prion Protein Transcription

(2020) Laia Lidón et al.   MOLECULAR NEUROBIOLOGY

Distinct Conformations, Aggregation and Cellular Internalization of Different Tau Strains

(2019) Thomas K. Karikari et al.   Frontiers in Cellular Neuroscience

Aβ-induced acceleration of Alzheimer-related τ-pathology spreading and its association with prion protein

(2019) Luis Aragão Gomes et al.   ACTA NEUROPATHOLOGICA

Identification of prion protein-derived peptides of potential use in Alzheimer's disease therapy

(2018) Hanna Nieznanska et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Frontotemporal dementia with Parkinsonism linked to chromosome-17 mutations enhance tau oligomer formation

(2018) Sumihiro Maeda et al.   NEUROBIOLOGY OF AGING

Impact of the Cellular Prion Protein on Amyloid-β and 3PO-Tau Processing

(2018) Matthias Schmitz et al.   JOURNAL OF ALZHEIMERS DISEASE

Amyloidogenic cross-seeding of Tau protein: Transient emergence of structural variants of fibrils

(2018) Bartosz Nizynski et al.   PLoS One

An autopsy report of three kindred in a Gerstmann-Sträussler-Scheinker disease P105L family with a special reference to prion protein, tau, and beta-amyloid

(2018) Keisuke Ishizawa et al.   Brain and Behavior

Cellular Prion Protein Mediates the Disruption of Hippocampal Synaptic Plasticity by Soluble Tau In Vivo

(2018) Tomas Ondrejcak et al.   JOURNAL OF NEUROSCIENCE

Tau Oligomers: Cytotoxicity, Propagation, and Mitochondrial Damage

(2017) Scott S. Shafiei et al.   Frontiers in Aging Neuroscience

Propagation of Tau aggregates

(2017) Michel Goedert et al.   Molecular Brain

Tau neurotoxicity and rescue in animal models of human Tauopathies

(2016) Lars Krüger et al.   CURRENT OPINION IN NEUROBIOLOGY

Soluble prion protein and its N-terminal fragment prevent impairment of synaptic plasticity by Aβ oligomers: Implications for novel therapeutic strategy in Alzheimer's disease

(2016) Jonah J. Scott-McKean et al.   NEUROBIOLOGY OF DISEASE

Extracellular Tau Oligomers Produce An Immediate Impairment of LTP and Memory

(2016) M. Fá et al.   Scientific Reports

The twenty-four KDa C-terminal tau fragment increases with aging in tauopathy mice: implications of prion-like properties

(2015) Shin-Ei Matsumoto et al.   HUMAN MOLECULAR GENETICS

A mechanistic model of tau amyloid aggregation based on direct observation of oligomers

(2015) Sarah L. Shammas et al.   Nature Communications

Advances in Therapeutics for Neurodegenerative Tauopathies: Moving toward the Specific Targeting of the Most Toxic Tau Species

(2014) Julia E. Gerson et al.   ACS Chemical Neuroscience

Stages and Conformations of the Tau Repeat Domain during Aggregation and Its Effect on Neuronal Toxicity

(2014) Satish Kumar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oligomer Formation of Tau Protein Hyperphosphorylated in Cells

(2014) Katharina Tepper et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Passive Immunization with Tau Oligomer Monoclonal Antibody Reverses Tauopathy Phenotypes without Affecting Hyperphosphorylated Neurofibrillary Tangles

(2014) D. L. Castillo-Carranza et al.   JOURNAL OF NEUROSCIENCE

Role of PrPC Expression in Tau Protein Levels and Phosphorylation in Alzheimer’s Disease Evolution

(2014) C. Vergara et al.   MOLECULAR NEUROBIOLOGY

Aβ induces its own prion protein N-terminal fragment (PrPN1)–mediated neutralization in amorphous aggregates

(2014) Maxime Béland et al.   NEUROBIOLOGY OF AGING

A PrPC-caveolin-Lyn complex negatively controls neuronal GSK3β and serotonin 1B receptor

(2014) Julia Hernandez-Rapp et al.   Scientific Reports

Characterization of tau oligomeric seeds in progressive supranuclear palsy

(2014) Julia E Gerson et al.   Acta Neuropathologica Communications

Hyperphosphorylation-Induced Tau Oligomers

(2013) Khalid Iqbal et al.   Frontiers in Neurology

Small Misfolded Tau Species Are Internalized via Bulk Endocytosis and Anterogradely and Retrogradely Transported in Neurons

(2012) Jessica W. Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau

(2012) Cristian A. Lasagna-Reeves et al.   Scientific Reports

The cellular prion protein mediates neurotoxic signalling of β-sheet-rich conformers independent of prion replication

(2011) Ulrike K Resenberger et al.   EMBO JOURNAL

α-Secretase-derived Fragment of Cellular Prion, N1, Protects against Monomeric and Oligomeric Amyloid β (Aβ)-associated Cell Death

(2011) Marie-Victoire Guillot-Sestier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice

(2011) Cristian A Lasagna-Reeves et al.   Molecular Neurodegeneration

Phosphorus Dendrimers Affect Alzheimer’s (Aβ1–28) Peptide and MAP-Tau Protein Aggregation

(2011) Tomasz Wasiak et al.   MOLECULAR PHARMACEUTICS

The Many Faces of Tau

(2011) Meaghan Morris et al.   NEURON

Tau, prions and Aβ: the triad of neurodegeneration

(2010) Lilla Reiniger et al.   ACTA NEUROPATHOLOGICA

Heparin Binding by Murine Recombinant Prion Protein Leads to Transient Aggregation and Formation of RNA-Resistant Species

(2010) Tuane C. R. G. Vieira et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Prion Diseases and Their Biochemical Mechanisms†

(2009) Nathan J. Cobb et al.   BIOCHEMISTRY

Propagation of Tau Misfolding from the Outside to the Inside of a Cell

(2009) Bess Frost et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cellular prion protein mediates impairment of synaptic plasticity by amyloid-β oligomers

(2009) Juha Laurén et al.   NATURE

A Soluble Oligomer of Tau Associated with Fiber Formation Analyzed by NMR

(2008) Dylan W. Peterson et al.   BIOCHEMISTRY

Ultrastructural study of florid plaques in variant Creutzfeldt-Jakob disease: a comparison with amyloid plaques in kuru, sporadic Creutzfeldt-Jakob disease and Gerstmann-Sträussler-Scheinker disease

(2008) B. Sikorska et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Tauopathy in human and experimental variant Creutzfeldt-Jakob disease

(2007) G. Giaccone et al.   NEUROBIOLOGY OF AGING