Neuroprotective role of apocynin against pentylenetetrazole kindling epilepsy and associated comorbidities in mice by suppression of ROS/RNS

Betahistine, prevents kindling, ameliorates the behavioral comorbidities and neurodegeneration induced by pentylenetetrazole

(2020) Azadeh Yazdi et al.   EPILEPSY & BEHAVIOR

Determination of levels of oxidative stress and nitrosative stress in patients with epilepsy

(2020) Serpil Ersan et al.   EPILEPSY RESEARCH

Inhibition of NADPH Oxidases Activity by Diphenyleneiodonium Chloride as a Mechanism of Senescence Induction in Human Cancer Cells

(2020) Katarzyna Piszczatowska et al.   Antioxidants

Immunohistochemical Study of Antioxidant Enzymes Regulated by Nrf2 in the Models of Epileptic Seizures (KA and PTZ)

(2019) María Fernanda Munguía-Martínez et al.   Oxidative Medicine and Cellular Longevity

Cellular and Molecular Differences Between Area CA1 and the Dentate Gyrus of the Hippocampus

(2019) Karim A Alkadhi   MOLECULAR NEUROBIOLOGY

NADPH oxidase regulates paraquat and maneb-induced dopaminergic neurodegeneration through ferroptosis

(2019) Liyan Hou et al.   TOXICOLOGY

Inhibition of NADPH oxidase by apocynin prevents learning and memory deficits in a mouse Parkinson's disease model

(2019) Liyan Hou et al.   Redox Biology

Oxidative stress and Parkinson’s disease: conflict of oxidant-antioxidant systems

(2019) Mohsen Hemmati-Dinarvand et al.   NEUROSCIENCE LETTERS

Propionate relieves pentylenetetrazol-induced seizures, consequent mitochondrial disruption, neuron necrosis and neurological deficits in mice

(2019) Yahong Cheng et al.   BIOCHEMICAL PHARMACOLOGY

Neuroprotective Effects of Apocynin and Galantamine During the Chronic Administration of Scopolamine in an Alzheimer’s Disease Model

(2019) Eliezer Joseph et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Hydrogen sulfide attenuates hyperhomocysteinemia-induced mitochondrial dysfunctions in brain

(2019) Mohit Kumar et al.   MITOCHONDRION

Berberine alleviates amyloid-beta pathology in the brain of APP/PS1 transgenic mice via inhibiting β/γ-secretases activity and enhancing α-secretases

(2018) Zhiyou Cai et al.   Current Alzheimer Research

Estrogen and Serotonin: Complexity of Interactions and Implications for Epileptic Seizures and Epileptogenesis

(2018) Faheem Hyder Pottoo et al.   Current Neuropharmacology

Mechanisms underlying anticonvulsant and proconvulsant actions of norepinephrine

(2018) Maedeh Ghasemi et al.   NEUROPHARMACOLOGY

Apigenin reverses behavioural impairments and cognitive decline in kindled mice via CREB-BDNF upregulation in the hippocampus

(2018) Pallavi Sharma et al.   NUTRITIONAL NEUROSCIENCE

Kinetics and metabolism of apocynin in the mouse brain assessed with positron-emission tomography

(2018) Toshimitsu Okamura et al.   PHYTOMEDICINE

Prevention of pentylenetetrazole-induced kindling and behavioral comorbidities in mice by levetiracetam combined with the GLP-1 agonist liraglutide: Involvement of brain antioxidant and BDNF upregulating properties

(2018) Alana Gomes de Souza et al.   BIOMEDICINE & PHARMACOTHERAPY

5-HT1A receptor agonist 8-OH-DPAT induces serotonergic behaviors in mice via interaction between PKCδ and p47phox

(2018) Hai-Quyen Tran et al.   FOOD AND CHEMICAL TOXICOLOGY

Combined NADPH and the NOX inhibitor apocynin provides greater anti-inflammatory and neuroprotective effects in a mouse model of stroke

(2017) Yuan-Yuan Qin et al.   FREE RADICAL BIOLOGY AND MEDICINE

Parallel basal ganglia circuits for decision making

(2017) Okihide Hikosaka et al.   JOURNAL OF NEURAL TRANSMISSION

Apocynin protects against neurological damage induced by quinolinic acid by an increase in glutathione synthesis and Nrf2 levels

(2017) Silvia Cruz-Álvarez et al.   NEUROSCIENCE

Protective effect of spermine against pentylenetetrazole kindling epilepsy induced comorbidities in mice

(2017) Mandeep Kumar et al.   NEUROSCIENCE RESEARCH

Ultrafine carbon particles promote rotenone-induced dopamine neuronal loss through activating microglial NADPH oxidase

(2017) Yinxi Wang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

p47Phox/CDK5/DRP1-Mediated Mitochondrial Fission Evokes PV Cell Degeneration in the Rat Dentate Gyrus Following Status Epilepticus

(2017) Ji-Eun Kim et al.   Frontiers in Cellular Neuroscience

Neuronal Nitric Oxide Synthase Contributes to PTZ Kindling Epilepsy-Induced Hippocampal Endoplasmic Reticulum Stress and Oxidative Damage

(2017) Xinjian Zhu et al.   Frontiers in Cellular Neuroscience

Proteinopathy, oxidative stress and mitochondrial dysfunction: cross talk in Alzheimer's disease and Parkinson's disease

(2017) Gargi Ganguly et al.   Drug Design Development and Therapy

The NADPH oxidase NOX2 mediates loss of parvalbumin interneurons in traumatic brain injury: human autoptic immunohistochemical evidence

(2017) Stefania Schiavone et al.   Scientific Reports

Neuropathology of childhood-onset basal ganglia degeneration caused by mutation of VAC14

(2017) Chloe Stutterd et al.   Annals of Clinical and Translational Neurology

A combination of NMDA and AMPA receptor antagonists retards granule cell dispersion and epileptogenesis in a model of acquired epilepsy

(2017) Alina Schidlitzki et al.   Scientific Reports

NADPH oxidase activation is required for pentylenetetrazole kindling-induced hippocampal autophagy

(2016) Xinjian Zhu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Apocynin prevents mitochondrial burdens, microglial activation, and pro-apoptosis induced by a toxic dose of methamphetamine in the striatum of mice via inhibition of p47phox activation by ERK

(2016) Duy-Khanh Dang et al.   Journal of Neuroinflammation

Ameliorative effect of kolaviron, a biflavonoid complex from Garcinia kola seeds against scopolamine-induced memory impairment in rats: role of antioxidant defense system

(2016) Ismail O. Ishola et al.   METABOLIC BRAIN DISEASE

Neurochemical modulation involved in the beneficial effect of liraglutide, GLP-1 agonist on PTZ kindling epilepsy-induced comorbidities in mice

(2016) Prashant Koshal et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Protective Effect of Nerolidol Against Pentylenetetrazol-Induced Kindling, Oxidative Stress and Associated Behavioral Comorbidities in Mice

(2016) Dilpreet Kaur et al.   NEUROCHEMICAL RESEARCH

Oxidative stress and mitochondrial dysfunction-linked neurodegenerative disorders

(2016) Md. Torequl Islam   NEUROLOGICAL RESEARCH

Evolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target Engagement

(2015) Sebastian Altenhöfer et al.   ANTIOXIDANTS & REDOX SIGNALING

Effect of GLT-1 modulator and P2X7 antagonists alone and in combination in the kindling model of epilepsy in rats

(2015) Neha Soni et al.   EPILEPSY & BEHAVIOR

Contribution of amygdala pathology to comorbid emotional disturbances in temporal lobe epilepsy

(2015) Deniz Yilmazer-Hanke et al.   JOURNAL OF NEUROSCIENCE RESEARCH

NOX2 Mediated-Parvalbumin Interneuron Loss Might Contribute to Anxiety-Like and Enhanced Fear Learning Behavior in a Rat Model of Post-Traumatic Stress Disorder

(2015) Fang-fang Liu et al.   MOLECULAR NEUROBIOLOGY

Microcircuits and their interactions in epilepsy: is the focus out of focus?

(2015) Jeanne T Paz et al.   NATURE NEUROSCIENCE

Apocynin attenuates isoproterenol-induced myocardial injury and fibrogenesis

(2014) Li Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

NADPH oxidases: an overview from structure to innate immunity-associated pathologies

(2014) Arvind Panday et al.   Cellular & Molecular Immunology

Apocynin, a Low Molecular Oral Treatment for Neurodegenerative Disease

(2014) Bert A. ‘t Hart et al.   Biomed Research International

Molecular Mechanisms of the Crosstalk Between Mitochondria and NADPH Oxidase Through Reactive Oxygen Species—Studies in White Blood Cells and in Animal Models

(2013) Swenja Kröller-Schön et al.   ANTIOXIDANTS & REDOX SIGNALING

Issues related to symptomatic and disease-modifying treatments affecting cognitive and neuropsychiatric comorbidities of epilepsy

(2013) Amy R. Brooks-Kayal et al.   EPILEPSIA

Anti-inflammatory effects of apocynin, an inhibitor of NADPH oxidase, in airway inflammation

(2011) So Yong Kim et al.   IMMUNOLOGY AND CELL BIOLOGY

Effect of Apocynin, an inhibitor of NADPH oxidase, in the inflammatory process induced by an experimental model of spinal cord injury

(2010) Daniela Impellizzeri et al.   FREE RADICAL RESEARCH

Effect of carvedilol on behavioral, mitochondrial dysfunction, and oxidative damage against d-galactose induced senescence in mice

(2009) Anil Kumar et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Neuromelanin Activates Microglia and Induces Degeneration of Dopaminergic Neurons: Implications for Progression of Parkinson’s Disease

(2009) Wei Zhang et al.   NEUROTOXICITY RESEARCH

IL-6 Mediated Degeneration of Forebrain GABAergic Interneurons and Cognitive Impairment in Aged Mice through Activation of Neuronal NADPH Oxidase

(2009) Laura L. Dugan et al.   PLoS One