Electrochemical Oxo‐Fluorosulfonylation of Alkynes under Air: Facile Access to β‐Keto Sulfonyl Fluorides

The Emerging Applications of Sulfur(VI) Fluorides in Catalysis

(2021) Cayo Lee et al.   ACS Catalysis

Introducing A New Class of Sulfonyl Fluoride Hubs via Radical Chloro‐Fluorosulfonylation of Alkynes

(2021) Xingliang Nie et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Electrochemically Enabled Intramolecular Aminooxygenation of Alkynes via Amidyl Radical Cyclization

(2020) Zhong‐Wei Hou et al.   CHINESE JOURNAL OF CHEMISTRY

Synthesis of Sulfonyl Fluorides from Sulfonamides

(2020) Marina Pérez-Palau et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Sulfocoumarins as dual inhibitors of human carbonic anhydrase isoforms IX/XII and of human thioredoxin reductase

(2020) Mikhail Krasavin et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Potent Reductants via Electron-Primed Photoredox Catalysis: Unlocking Aryl Chlorides for Radical Coupling

(2020) Nicholas G. W. Cowper et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Reductive Electrophotocatalysis: Merging Electricity and Light To Achieve Extreme Reduction Potentials

(2020) Hyunwoo Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Electrochemical Oxidative Oxydihalogenation of Alkynes for the Synthesis of α,α-Dihaloketones

(2020) Xiangtai Meng et al.   ORGANIC LETTERS

Arenesulfonyl Fluoride Synthesis via Copper-Catalyzed Fluorosulfonylation of Arenediazonium Salts

(2020) Yongan Liu et al.   ORGANIC LETTERS

Silicon‐Free SuFEx Reactions of Sulfonimidoyl Fluorides: Scope, Enantioselectivity, and Mechanism

(2020) Dong‐Dong Liang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Diversity Oriented Clicking (DOC): Divergent Synthesis of SuFExable Pharmacophores From 2‐Substituted‐Alkynyl‐1‐Sulfonyl Fluoride (SASF) Hubs

(2020) Christopher J Smedley et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemical‐Reductant‐Free Electrochemical Deuteration Reaction using Deuterium Oxide

(2020) Xu Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

SuFEx-enabled high-throughput medicinal chemistry

(2020) Seiya Kitamura et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Decarboxylative Thiolation of Redox-Active Esters to Thioesters by Merging Photoredox and Copper Catalysis

(2020) Tianxiao Xu et al.   ORGANIC LETTERS

Copper-free Sandmeyer-type Reaction for the Synthesis of Sulfonyl Fluorides

(2020) Tao Zhong et al.   ORGANIC LETTERS

SuFEx Activation with Ca(NTf2)2: A Unified Strategy to Access Sulfamides, Sulfamates, and Sulfonamides from S(VI) Fluorides

(2020) Subham Mahapatra et al.   ORGANIC LETTERS

Rationally Designed Covalent BCL6 Inhibitor That Targets a Tyrosine Residue in the Homodimer Interface

(2020) Mingxing Teng et al.   ACS Medicinal Chemistry Letters

Research and Development on Therapeutic Agents and Vaccines for COVID-19 and Related Human Coronavirus Diseases

(2020) Cynthia Liu et al.   ACS Central Science

Electrode Materials in Modern Organic Electrochemistry

(2020) David Heard et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

New coumarin/sulfocoumarin linked phenylacrylamides as selective transmembrane carbonic anhydrase inhibitors: Synthesis and in-vitro biological evaluation

(2020) Baijayantimala Swain et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Developing Covalent Protein Drugs via Proximity-Enabled Reactive Therapeutics

(2020) Qingke Li et al.   CELL

New Redox Strategies in Organic Synthesis by Means of Electrochemistry and Photochemistry

(2020) Jinjian Liu et al.   ACS Central Science

A Unified Strategy for Arylsulfur(VI) Fluorides from Aryl Halides: Access to Ar‒SOF3 Compounds

(2020) Lin Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Perspective on Organic Electrochemistry

(2020) R. Daniel Little   JOURNAL OF ORGANIC CHEMISTRY

Electrochemical Oxidative Functionalization of Arylalkynes: Access to α,α‐Dibromo Aryl Ketones

(2020) Dan Wang et al.   ADVANCED SYNTHESIS & CATALYSIS

Radical Fluorosulfonylation: Accessing Alkenyl Sulfonyl Fluorides from Alkenes

(2020) Xingliang Nie et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fluorosulfonylation of arenediazonium tetrafluoroborates with Na2S2O5 and N-fluorobenzenesulfonimide

(2020) Shuai Liu et al.   JOURNAL OF FLUORINE CHEMISTRY

An Electroreductive Approach to Radical Silylation via the Activation of Strong Si–Cl Bond

(2020) Lingxiang Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Electroreductive Carbofunctionalization of Alkenes with Alkyl Bromides via a Radical-Polar Crossover Mechanism

(2020) Wen Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The pine wood nematode Bursaphelenchus xylophilus and molecular diagnostic methods

(2020) Jin-Pyo Lee et al.   Molecular & Cellular Toxicology

Scalable and safe synthetic organic electroreduction inspired by Li-ion battery chemistry

(2019) Byron K. Peters et al.   SCIENCE

Synthesis of β-Arylethenesulfonyl Fluoride via Pd-Catalyzed Nondirected C–H Alkenylation

(2019) Xiao-Yue Chen et al.   ORGANIC LETTERS

Recent Advances on the Electrochemical Difunctionalization of Alkenes/Alkynes

(2019) Haibo Mei et al.   CHINESE JOURNAL OF CHEMISTRY

Bifluoride Ion Mediated SuFEx Trifluoromethylation of Sulfonyl Fluorides and Iminosulfur Oxydifluorides

(2019) Christopher J. Smedley et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

De Novo Synthesis of Highly Functionalized Benzimidazolones and Benzoxazolones through an Electrochemical Dehydrogenative Cyclization Cascade

(2019) Fan Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Specifically Generation of Singlet Oxygen via Russell Mechanism in Hypoxic Tumor and GSH Depletion by Cu-TCPP Nanosheets for Cancer Therapy

(2019) Chao Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly selective electrochemical hydrogenation of alkynes: Rapid construction of mechanochromic materials

(2019) Bijin Li et al.   Science Advances

Sulfonyl Fluoride Synthesis through Electrochemical Oxidative Coupling of Thiols and Potassium Fluoride

(2019) Gabriele Laudadio et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

DNA‐Encoded Libraries: Aryl Fluorosulfonates as Versatile Electrophiles Enabling Facile On‐DNA Suzuki, Sonogashira, and Buchwald Reactions

(2019) Hongtao Xu et al.   Advanced Science

Potential-Tuned Selective Electrosynthesis of Azoxy-, Azo- and Amino Aromatics over a CoP Nanosheet Cathode

(2019) Xiaodan Chong et al.   National Science Review

Metal-Free Synthesis of Functional 1-Substituted-1,2,3-Triazoles from Ethenesulfonyl Fluoride and Organic Azides

(2019) Marie-Claire Giel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cyclic Alkenylsulfonyl Fluorides: Palladium-Catalyzed Synthesis and Functionalization of Compact Multifunctional Reagents

(2019) Terry Shing-Bong Lou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Selective Deprotection of the Diphenylmethylsilyl (DPMS) Hydroxyl Protecting Group under Environmentally Responsible, Aqueous Conditions

(2019) Nnamdi Akporji et al.   ChemCatChem

Aryl-fluorosulfate-based Lysine Covalent Pan-Inhibitors of Apoptosis Protein (IAP) Antagonists with Cellular Efficacy

(2019) Carlo Baggio et al.   JOURNAL OF MEDICINAL CHEMISTRY

Modular click chemistry libraries for functional screens using a diazotizing reagent

(2019) Genyi Meng et al.   NATURE

Asymmetric Conjugate Addition of Ethylene Sulfonyl Fluorides to 3-Amido-2-oxindoles: Synthesis of Chiral Spirocyclic Oxindole Sultams

(2019) Jie Chen et al.   ORGANIC LETTERS

A rapid access to aliphatic sulfonyl fluorides

(2019) Ruting Xu et al.   Nature Communications

Rh(I)–Diene-Catalyzed Addition of (Hetero)aryl Functionality to 1,3-Dienylsulfonyl Fluorides Achieving Exclusive Regioselectivity and High Enantioselectivity: Generality and Mechanism

(2019) Balakrishna Moku et al.   ACS Catalysis

A Survival Guide for the “Electro-curious”

(2019) Cian Kingston et al.   ACCOUNTS OF CHEMICAL RESEARCH

Nickel-Catalyzed Electrochemical Reductive Relay Cross-Coupling of Alkyl Halides to Aryl Halides

(2019) Ke-Jin Jiao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Site-Selective, Modular Diversification of Polyhalogenated Aryl Fluorosulfates (ArOSO2 F) Enabled by an Air-Stable PdI Dimer

(2019) Marvin Mendel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Covalent Small Molecules as Enabling Platforms for Drug Discovery

(2019) Samuel E. Dalton et al.   CHEMBIOCHEM

Click chemistry: evolving on the fringe

(2019) Long Xu et al.   CHINESE JOURNAL OF CHEMISTRY

Electrochemical Synthesis of Hindered Primary and Secondary Amines via Proton-Coupled Electron Transfer

(2019) Dan Lehnherr et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Electrochemical Synthesis of Imidazo-Fused N-Heteroaromatic Compounds through a C−N Bond-Forming Radical Cascade

(2018) Zhong-Wei Hou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A New Portal to SuFEx Click Chemistry: A Stable Fluorosulfuryl Imidazolium Salt Emerging as an “F−SO2 +” Donor of Unprecedented Reactivity, Selectivity, and Scope

(2018) Taijie Guo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Electrifying Organic Synthesis

(2018) Anton Wiebe et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Arylfluorosulfate-Based Warheads for Covalent Protein Labeling: A New Addition to the Arsenal

(2018) Pablo Martin-Gago et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

1-Bromoethene-1-sulfonyl fluoride (BESF) is another good connective hub for SuFEx click chemistry

(2018) Christopher J. Smedley et al.   CHEMICAL COMMUNICATIONS

1-Bromoethene-1-sulfonyl fluoride (1-Br-ESF), a new SuFEx clickable reagent, and its application for regioselective construction of 5-sulfonylfluoro isoxazoles

(2018) Jing Leng et al.   CHEMICAL COMMUNICATIONS

Sulfonyl Fluorides (SFs): More Than Click Reagents?

(2018) Praveen K. Chinthakindi et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Potent and Highly Selective Inhibitors of the Proteasome Trypsin-like Site by Incorporation of Basic Side Chain Containing Amino Acid Derived Sulfonyl Fluorides

(2018) Raik Artschwager et al.   JOURNAL OF MEDICINAL CHEMISTRY

SuFEx Click Chemistry Enabled Late-Stage Drug Functionalization

(2018) Zilei Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Electrochemical Difluoromethylarylation of Alkynes

(2018) Peng Xiong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

SuFEx Postpolymerization Modification Kinetics and Reactivity in Polymer Brushes

(2018) Karson Brooks et al.   MACROMOLECULES

Introduction of a Crystalline, Shelf-Stable Reagent for the Synthesis of Sulfur(VI) Fluorides

(2018) Hua Zhou et al.   ORGANIC LETTERS

Regioselective Synthesis of Fluorosulfonyl 1,2,3-Triazoles from Bromovinylsulfonyl Fluoride

(2018) Joice Thomas et al.   ORGANIC LETTERS

Emerging Utility of Fluorosulfate Chemical Probes

(2018) Lyn H. Jones   ACS Medicinal Chemistry Letters

Ruthenium-Catalyzed Electrochemical Dehydrogenative Alkyne Annulation

(2018) Fan Xu et al.   ACS Catalysis

Autocatalytic Synthesis of Bifluoride Ionic Liquids by SuFEx Click Chemistry

(2018) Taha Hmissa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An Affinity-Based Probe for the Human Adenosine A2A Receptor

(2018) Xue Yang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Facile Synthesis of Sequence-Regulated Synthetic Polymers Using Orthogonal SuFEx and CuAAC Click Reactions

(2018) Cangjie Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Electrochemical Hydrogenation with Gaseous Ammonia

(2018) Jin Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

SO2F2-Mediated Oxidative Dehydrogenation and Dehydration of Alcohols to Alkynes

(2018) Gao-Feng Zha et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of Arenesulfonyl Fluorides via Sulfuryl Fluoride Incorporation from Arynes

(2018) Jungmin Kwon et al.   ORGANIC LETTERS

Pd-Catalyzed Conversion of Aryl Iodides to Sulfonyl Fluorides Using SO2 Surrogate DABSO and Selectfluor

(2017) Ariana L. Tribby et al.   JOURNAL OF ORGANIC CHEMISTRY

Bifluoride-catalysed sulfur(VI) fluoride exchange reaction for the synthesis of polysulfates and polysulfonates

(2017) Bing Gao et al.   Nature Chemistry

Electrooxidative Tandem Cyclization of Activated Alkynes with Sulfinic Acids To Access Sulfonated Indenones

(2017) Jiangwei Wen et al.   ORGANIC LETTERS

A Synthesis of “Dual Warhead” β-Aryl Ethenesulfonyl Fluorides and One-Pot Reaction to β-Sultams

(2017) Praveen K. Chinthakindi et al.   ORGANIC LETTERS

One-pot palladium-catalyzed synthesis of sulfonyl fluorides from aryl bromides

(2017) Alyn T. Davies et al.   Chemical Science

Electrochemical C−H/N−H Functionalization for the Synthesis of Highly Functionalized (Aza)indoles

(2016) Zhong-Wei Hou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Heck-Matsuda Process for the Synthesis of β-Arylethenesulfonyl Fluorides: Selectively Addressable Bis-electrophiles for SuFEx Click Chemistry

(2016) Hua-Li Qin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Organocatalyzed Transformations of β-Ketoesters

(2016) Thavendran Govender et al.   CHEMICAL REVIEWS

Sulfonyl fluorides as privileged warheads in chemical biology

(2015) Arjun Narayanan et al.   Chemical Science

Sulfur(VI) Fluoride Exchange (SuFEx): Another Good Reaction for Click Chemistry

(2014) Jiajia Dong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

SuFEx-Based Synthesis of Polysulfates

(2014) Jiajia Dong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Aerobic Oxidation in Nanomicelles of Aryl Alkynes, in Water at Room Temperature

(2014) Sachin Handa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Redox catalysis in organic electrosynthesis: basic principles and recent developments

(2014) Robert Francke et al.   CHEMICAL SOCIETY REVIEWS

7-Substituted-sulfocoumarins are isoform-selective, potent carbonic anhydrase II inhibitors

(2013) Muhammet Tanc et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Thermally Persistent Fluorosulfonyl Nitrene and Unexpected Formation of the Fluorosulfonyl Radical

(2013) Xiaoqing Zeng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dioxygen-Triggered Oxidative Radical Reaction: Direct Aerobic Difunctionalization of Terminal Alkynes toward β-Keto Sulfones

(2013) Qingquan Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Sulfocoumarins (1,2-Benzoxathiine-2,2-dioxides): A Class of Potent and Isoform-Selective Inhibitors of Tumor-Associated Carbonic Anhydrases

(2012) Kaspars Tars et al.   JOURNAL OF MEDICINAL CHEMISTRY

The Colletotrichum gloeosporioides species complex

(2012) B.S. Weir et al.   STUDIES IN MYCOLOGY

Colletotrichum – current status and future directions

(2012) P.F. Cannon et al.   STUDIES IN MYCOLOGY

Synthesis of β-, γ-, δ-, ..., ω-Halogenated Ketones and Aldehydes

(2010) Bart I. Roman et al.   CHEMICAL REVIEWS

1,3-Dicarbonyl compounds in stereoselective domino and multicomponent reactions

(2010) Damien Bonne et al.   TETRAHEDRON-ASYMMETRY