Rhodium‐Catalyzed Asymmetric Hydrogenation of 3‐Benzoylaminocoumarins for the Synthesis of Chiral 3‐Amino Dihydrocoumarins

Asymmetric Transfer Hydrogenation of α-Substituted-β-Keto Carbonitriles via Dynamic Kinetic Resolution

(2021) Fangyuan Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantio‐ and Diastereoselective, Complete Hydrogenation of Benzofurans by Cascade Catalysis

(2021) Daniel Moock et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Backbone-Modified C2-Symmetrical Chiral Bisphosphine TMS-QuinoxP*: Asymmetric Borylation of Racemic Allyl Electrophiles

(2021) Hiroaki Iwamoto et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cobalt‐Catalyzed Chemo‐ and Enantioselective Hydrogenation of Conjugated Enynes

(2021) Yanhua Hu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantiodivergent Synthesis of Chiral Tetrahydroquinoline Derivatives via Ir-Catalyzed Asymmetric Hydrogenation: Solvent-Dependent Enantioselective Control and Mechanistic Investigations

(2021) Zhengyu Han et al.   ACS Catalysis

Nickel-Catalyzed Asymmetric Hydrogenation of 2-Amidoacrylates

(2020) Yawen Hu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cobalt-Catalyzed Asymmetric Hydrogenation of α,β-Unsaturated Carboxylic Acids by Homolytic H2 Cleavage

(2020) Hongyu Zhong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Design of Ru(II)-NHC-Diamine Precatalysts Directed by Ligand Cooperation: Applications and Mechanistic Investigations for Asymmetric Hydrogenation

(2020) Wei Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Amino Acid Schiff Base Bearing Benzophenone Imine As a Platform for Highly Congested Unnatural α-Amino Acid Synthesis

(2020) Yohei Matsumoto et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Reductive Coupling of Imines Templated by Chiral Diboron

(2020) Mingkang Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective hydrogenation of dialkyl ketones

(2020) Feng-Hua Zhang et al.   Nature Catalysis

Phosphorus Ligands from the Zhang lab: Design, Asymmetric Hydrogenation, and Industrial Applications

(2020) Feng Wan et al.   CHINESE JOURNAL OF CHEMISTRY

Ni-catalyzed asymmetric hydrogenation of N-aryl imino esters for the efficient synthesis of chiral α-aryl glycines

(2020) Dan Liu et al.   Nature Communications

Highly Efficient Enantioselective Synthesis of Chiral Sulfones by Rh-Catalyzed Asymmetric Hydrogenation

(2019) Qiaozhi Yan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ni-Catalyzed Asymmetric Hydrogenation of N-Sulfonyl Imines

(2019) Bowen Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Selective Arene Hydrogenation Provides Direct Access to Saturated Carbo- and Heterocycles

(2019) Mario Patrick Wiesenfeldt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

P-Chiral Phosphorus Ligands Based on a 2,3-Dihydrobenzo[d][1,3]oxaphosphole Motif for Asymmetric Catalysis

(2019) Guangqing Xu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Chemo- and Enantioselective Hydrogenation of α-Formyl Enamides: An Efficient Access to Chiral α-Amido Aldehydes

(2019) Jian Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Approaches to Obtaining Fluorinated α-Amino Acids

(2019) Johann Moschner et al.   CHEMICAL REVIEWS

Cobalt-Catalyzed Asymmetric Hydrogenation of C=N Bonds Enabled by Assisted Coordination and Nonbonding Interactions

(2019) Yanhua Hu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Bulky Three-Hindered Quadrant Bisphosphine Ligand: Synthesis and Application in Rhodium-Catalyzed Asymmetric Hydrogenation of Functionalized Alkenes

(2019) Yuuki Sawatsugawa et al.   ORGANIC LETTERS

Biosynthetic Pathways to Nonproteinogenic α-Amino Acids

(2019) Jason B. Hedges et al.   CHEMICAL REVIEWS

Enzymatic asymmetric synthesis of chiral amino acids

(2018) Ya-Ping Xue et al.   CHEMICAL SOCIETY REVIEWS

Ir-Catalyzed Asymmetric Hydrogenation of α-Alkylidene β-Lactams and Cyclobutanones

(2018) Jingzhao Xia et al.   CHINESE JOURNAL OF CHEMISTRY

Chiral Cyclohexyl-Fused Spirobiindanes: Practical Synthesis, Ligand Development, and Asymmetric Catalysis

(2018) Zhiyao Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rapid Construction of Structurally Diverse Quinolizidines, Indolizidines, and Their Analogues via Ruthenium-Catalyzed Asymmetric Cascade Hydrogenation/Reductive Amination

(2018) Ya Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pd(OAc)2-catalyzed asymmetric hydrogenation of sterically hindered N-tosylimines

(2018) Jianzhong Chen et al.   Nature Communications

Small-Molecule Inhibitors of the Programmed Cell Death-1/Programmed Death-Ligand 1 (PD-1/PD-L1) Interaction via Transiently Induced Protein States and Dimerization of PD-L1

(2017) Katarzyna Guzik et al.   JOURNAL OF MEDICINAL CHEMISTRY

Chloride-Bridged Dinuclear Rhodium(III) Complexes Bearing Chiral Diphosphine Ligands: Catalyst Precursors for Asymmetric Hydrogenation of Simple Olefins

(2016) Yusuke Kita et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Hydrogenation of Nonaromatic Cyclic Substrates

(2016) Zhenfeng Zhang et al.   CHEMICAL REVIEWS

Unusual Amino Acids in Medicinal Chemistry

(2016) Mark A. T. Blaskovich   JOURNAL OF MEDICINAL CHEMISTRY

Asymmetric Hydrogenation of Cyclic Dehydroamino Acids and Their Derivatives

(2015) Yingjie Wang et al.   CHINESE JOURNAL OF ORGANIC CHEMISTRY

Electron-Deficient Diphosphines: The Impact of DIFLUORPHOS in Asymmetric Catalysis

(2014) Jean-Pierre Genet et al.   CHEMICAL REVIEWS

Discovery of 2-oxo-1,2-dihydrobenzo[cd]indole-6-sulfonamide derivatives as new RORγ inhibitors using virtual screening, synthesis and biological evaluation

(2014) Yan Zhang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Homogenous Pd-Catalyzed Asymmetric Hydrogenation of Unprotected Indoles: Scope and Mechanistic Studies

(2014) Ying Duan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

In Situ Synthesis of Neutral Dinuclear Rhodium Diphosphine Complexes [{Rh(diphosphine)(μ2-X)}2]: Systematic Investigations

(2014) Antje Meißner et al.   ChemPlusChem

ChenPhos: Highly Modular P-StereogenicC1-Symmetric Diphosphine Ligands for the Efficient Asymmetric Hydrogenation of α-Substituted Cinnamic Acids

(2013) Weiping Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly enantioselective hydrogenation of N-unprotected indoles using (S)-C10–BridgePHOS as the chiral ligand

(2013) Chao Li et al.   TETRAHEDRON

Synthesis of axially chiral C10-BridgePHOS oxides and their use as organocatalysts in enantioselective allylations of aldehydes

(2013) Jianzhong Chen et al.   TETRAHEDRON

Palladium/Chiral Amine Co-catalyzed Enantioselective β-Arylation of α,β-Unsaturated Aldehydes

(2012) Ismail Ibrahem et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

SAR study of tyrosine–chlorambucil hybrid regioisomers; synthesis and biological evaluation against breast cancer cell lines

(2011) Caroline Descôteaux et al.   AMINO ACIDS

Asymmetric Hydrogenation of Heteroarenes and Arenes

(2011) Duo-Sheng Wang et al.   CHEMICAL REVIEWS

Rigid P-Chiral Phosphine Ligands with tert-Butylmethylphosphino Groups for Rhodium-Catalyzed Asymmetric Hydrogenation of Functionalized Alkenes

(2011) Tsuneo Imamoto et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Electron-Donating and Rigid P-Stereogenic Bisphospholane Ligands for Highly Enantioselective Rhodium-Catalyzed Asymmetric Hydrogenations

(2010) Xiaowei Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Design, synthesis, and in vivo characterization of a novel series of tetralin amino imidazoles as γ-secretase inhibitors: Discovery of PF-3084014

(2010) Michael A. Brodney et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Transition Metal-Catalyzed Enantioselective Hydrogenation of Enamines and Imines

(2010) Jian-Hua Xie et al.   CHEMICAL REVIEWS

From tropos to atropos: 5,5′-bridged 2,2′-bis(diphenylphosphino)biphenyls as chiral ligands for highly enantioselective palladium-catalyzed hydrogenation of α-phthalimide ketones

(2010) Changqing Wang et al.   TETRAHEDRON LETTERS

Asymmetric catalysis with 7-ring chelate diphosphines: DIOP, BINAP and conformational mobility

(2010) Jevgenij A. Raskatov et al.   TETRAHEDRON-ASYMMETRY

Advances toward New Antidepressants with Dual Serotonin Transporter and 5-HT1AReceptor Affinity within a Class of 3-Aminochroman Derivatives. Part 2

(2008) Nicole T. Hatzenbuhler et al.   JOURNAL OF MEDICINAL CHEMISTRY

Novel 3-Carboxamide-coumarins as Potent and Selective FXIIa Inhibitors

(2008) Séverine Robert et al.   JOURNAL OF MEDICINAL CHEMISTRY

Asymmetric Hydrogenation Catalyzed by a Rhodium Complex of (R)-(tert-Butylmethylphosphino)(di-tert-butylphosphino)methane:  Scope of Enantioselectivity and Mechanistic Study

(2008) Ilya D. Gridnev et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY