Rational Design of a Two‐Photon Fluorescent Probe for Human Cytochrome P450 3A and the Visualization of Mechanism‐Based Inactivation

A near-infrared ratiometric fluorescent probe for selectively tracking human cytochrome P450 3A5 in living cells and tumor-bearing mice

(2021) Hefang Ji et al.   SENSORS AND ACTUATORS B-CHEMICAL

Molecular‐splicing strategy to construct a near‐infrared fluorescent probe for UDP‐glucuronosyltransferase1A1

(2021) Xiaochi Ma et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fluorescent probes for the detection and imaging of Cytochrome P450

(2021) Lei Feng et al.   COORDINATION CHEMISTRY REVIEWS

Activity‐Based NIR Enzyme Fluorescent Probes for the Diagnosis of Tumors and Image‐Guided Surgery

(2020) Juyoung Yoon et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Molecular probes for human cytochrome P450 enzymes: Recent progress and future perspectives

(2020) Jingjing Wu et al.   COORDINATION CHEMISTRY REVIEWS

Visualizing Microglia with a Fluorescence Turn-On Ugt1a7c Substrate

(2019) Beomsue Kim et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Targeted Enzyme Activated Two-Photon Fluorescent Probes: A Case Study of CYP3A4 Using a Two-Dimensional Design Strategy

(2019) Jing Ning et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Molecular optical imaging probes for early diagnosis of drug-induced acute kidney injury

(2019) Jiaguo Huang et al.   NATURE MATERIALS

Inter-Individual Variation in CYP3A Activity Influences Lapatinib Bioactivation

(2019) Jennifer E. Bissada et al.   DRUG METABOLISM AND DISPOSITION

Validation of a 3-h Sampling Interval to Assess Variability in Cytochrome P450 3A Phenotype and the Impact of Induction and Mechanism-Based Inhibition Using Midazolam as a Probe Substrate

(2019) Madelé van Dyk et al.   Frontiers in Pharmacology

Design and Mechanism of GABA Aminotransferase Inactivators. Treatments for Epilepsies and Addictions

(2018) Richard B. Silverman   CHEMICAL REVIEWS

Rationally Designed Fluorescence . OH Probe with High Sensitivity and Selectivity for Monitoring the Generation of . OH in Iron Autoxidation without Addition of H2 O2

(2018) Hongyu Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent progresses in small-molecule enzymatic fluorescent probes for cancer imaging

(2018) Hong-Wen Liu et al.   CHEMICAL SOCIETY REVIEWS

Molecular Design Strategy to Construct the Near-Infrared Fluorescent Probe for Selectively Sensing Human Cytochrome P450 2J2

(2018) Jing Ning et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Positional isomeric chemosensors: fluorescent and colorimetric cyanide detection based on Si–O cleavage

(2017) Yayun Chen et al.   NEW JOURNAL OF CHEMISTRY

A highly sensitive and selective fluorescent probe for N2H4 in air and living cells

(2017) Jie Cui et al.   NEW JOURNAL OF CHEMISTRY

Metabolism of aflatoxins: key enzymes and interindividual as well as interspecies differences

(2014) Vlastimil Dohnal et al.   ARCHIVES OF TOXICOLOGY

Mechanism-based Inhibition of CYP450: An Indicator of Drug-induced Hepatotoxicity

(2013) Shan Feng et al.   CURRENT DRUG METABOLISM

An Off–On COX-2-Specific Fluorescent Probe: Targeting the Golgi Apparatus of Cancer Cells

(2013) Hua Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Determination of Time-Dependent Inactivation of CYP3A4 in Cryopreserved Human Hepatocytes and Assessment of Human Drug-Drug Interactions

(2011) Y. Chen et al.   DRUG METABOLISM AND DISPOSITION

CYP3A Time-Dependent Inhibition Risk Assessment Validated with 400 Reference Drugs

(2011) A. Zimmerlin et al.   DRUG METABOLISM AND DISPOSITION

Application of mechanism-based CYP inhibition for predicting drug–drug interactions

(2009) Zhi-Wei Zhou et al.   Expert Opinion on Drug Metabolism & Toxicology

Comparison of Kinetic Parameters for Drug Oxidation Rates and Substrate Inhibition Potential Mediated by Cytochrome P450 3A4 and 3A5

(2008) Hiroshi Yamazaki et al.   CURRENT DRUG METABOLISM

Potential role of intestinal first-pass metabolism in the prediction of drug–drug interactions

(2008) Aleksandra Galetin et al.   Expert Opinion on Drug Metabolism & Toxicology