Molecular optical imaging probes for early diagnosis of drug-induced acute kidney injury

Near-Infrared Fluorescent Molecular Probe for Sensitive Imaging of Keloid

(2018) Qingqing Miao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Advances in predictive in vitro models of drug-induced nephrotoxicity

(2018) Joanne Y.-C. Soo et al.   Nature Reviews Nephrology

Paradigms of acute kidney injury in the intensive care setting

(2018) John A. Kellum et al.   Nature Reviews Nephrology

Diagnostic work-up and specific causes of acute kidney injury

(2017) Michael Darmon et al.   INTENSIVE CARE MEDICINE

Glomerular barrier behaves as an atomically precise bandpass filter in a sub-nanometre regime

(2017) Bujie Du et al.   Nature Nanotechnology

Towards clinically translatable in vivo nanodiagnostics

(2017) Seung-min Park et al.   Nature Reviews Materials

Near-infrared fluorophores for biomedical imaging

(2017) Guosong Hong et al.   Nature Biomedical Engineering

Real-time in vivo imaging reveals localised Nrf2 stress responses associated with direct and metabolism-dependent drug toxicity

(2017) Shiva S. Forootan et al.   Scientific Reports

Tissue-Specific Near-Infrared Fluorescence Imaging

(2016) Eric A. Owens et al.   ACCOUNTS OF CHEMICAL RESEARCH

Superoxide Ion: Generation and Chemical Implications

(2016) Maan Hayyan et al.   CHEMICAL REVIEWS

Remarkable Enhancement of Chemiluminescent Signal by Dioxetane–Fluorophore Conjugates: Turn-ON Chemiluminescence Probes with Color Modulation for Sensing and Imaging

(2016) Nir Hananya et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Real-Time Tracking and In Vivo Visualization of β-Galactosidase Activity in Colorectal Tumor with a Ratiometric Near-Infrared Fluorescent Probe

(2016) Kaizhi Gu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dichloroacetate Prevents Cisplatin-Induced Nephrotoxicity without Compromising Cisplatin Anticancer Properties

(2016) R. Galgamuwa et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Radiologic imaging of the renal parenchyma structure and function

(2016) Nicolas Grenier et al.   Nature Reviews Nephrology

Fluorescent Probe HKSOX-1 for Imaging and Detection of Endogenous Superoxide in Live Cells and In Vivo

(2015) Jun Jacob Hu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A small-molecule dye for NIR-II imaging

(2015) Alexander L. Antaris et al.   NATURE MATERIALS

Structure-inherent targeting of near-infrared fluorophores for parathyroid and thyroid gland imaging

(2015) Hoon Hyun et al.   NATURE MEDICINE

Sepsis-Associated Acute Kidney Injury

(2015) Rashid Alobaidi et al.   SEMINARS IN NEPHROLOGY

Oxidative stress and autophagy: Crucial modulators of kidney injury

(2015) Angara Sureshbabu et al.   Redox Biology

Real-time imaging of oxidative and nitrosative stress in the liver of live animals for drug-toxicity testing

(2014) Adam J Shuhendler et al.   NATURE BIOTECHNOLOGY

Acute Kidney Injury and Chronic Kidney Disease as Interconnected Syndromes

(2014) Lakhmir S. Chawla et al.   NEW ENGLAND JOURNAL OF MEDICINE

Protective effect of hydrogen sulfide on gentamicin-induced renal injury

(2014) Alper Otunctemur et al.   RENAL FAILURE

Acute kidney injury: an increasing global concern

(2013) Norbert H Lameire et al.   LANCET

Three feasible strategies to minimize kidney injury in 'incipient AKI'

(2013) Mark A. Perazella et al.   Nature Reviews Nephrology

Reaction-based small-molecule fluorescent probes for chemoselective bioimaging

(2012) Jefferson Chan et al.   Nature Chemistry

Chemistry and biology of reactive oxygen species in signaling or stress responses

(2011) Bryan C Dickinson et al.   Nature Chemical Biology

Maltodextrin-based imaging probes detect bacteria in vivo with high sensitivity and specificity

(2011) Xinghai Ning et al.   NATURE MATERIALS

Porphysome nanovesicles generated by porphyrin bilayers for use as multimodal biophotonic contrast agents

(2011) Jonathan F. Lovell et al.   NATURE MATERIALS

The Ngal reporter mouse detects the response of the kidney to injury in real time

(2011) Neal Paragas et al.   NATURE MEDICINE

Plasma Biomarkers of Oxidant Stress and Development of Organ Failure in Severe Sepsis

(2011) Lorraine B. Ware et al.   SHOCK

Urinary biomarkers trefoil factor 3 and albumin enable early detection of kidney tubular injury

(2010) Yan Yu et al.   NATURE BIOTECHNOLOGY

Urinary clusterin, cystatin C, β2-microglobulin and total protein as markers to detect drug-induced kidney injury

(2010) Frank Dieterle et al.   NATURE BIOTECHNOLOGY

A panel of urinary biomarkers to monitor reversibility of renal injury and a serum marker with improved potential to assess renal function

(2010) Josef S Ozer et al.   NATURE BIOTECHNOLOGY

Kidney injury molecule-1 outperforms traditional biomarkers of kidney injury in preclinical biomarker qualification studies

(2010) Vishal S Vaidya et al.   NATURE BIOTECHNOLOGY

Second window for in vivo imaging

(2009) Andrew M. Smith et al.   Nature Nanotechnology

Fluorescent Silica Nanoparticles with Efficient Urinary Excretion for Nanomedicine

(2008) Andrew A. Burns et al.   NANO LETTERS

Molecular imaging in drug development

(2008) Jürgen K. Willmann et al.   NATURE REVIEWS DRUG DISCOVERY