Construction of C−C Axial Chirality via Asymmetric Carbene Insertion into Arene C−H Bonds

Synthesis of Axially Chiral 2,2′-Bisphosphobiarenes via a Nickel-Catalyzed Asymmetric Ullmann Coupling: General Access to Privileged Chiral Ligands without Optical Resolution

(2021) Ziqing Zuo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Atroposelective Coupling–Cyclization of 2-Isocyanobenzamides to Construct Axially Chiral 2-Aryl- and 2,3-Diarylquinazolinones

(2021) Fan Teng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Regiospecific and Enantioselective Arylvinylcarbene Insertion of a C–H Bond of Aniline Derivatives Enabled by a Rh(I)-Diene Catalyst

(2021) Dong-Xing Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Oxygen‐linked Cyclopentadienyl Rh(III) Complexes‐Catalyzed Asymmetric C−H Arylation of Benzo[h]quinolines with 1‐Diazonaphthoquinones

(2021) Chong-Qing Pan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent Advances in Catalytic Asymmetric Construction of Atropisomers

(2021) Jun Kee Cheng et al.   CHEMICAL REVIEWS

Highly Atroposelective Rhodium(II)-Catalyzed N–H Bond Insertion: Access to Axially Chiral N-Arylindolocarbazoles

(2021) Qiao Ren et al.   ACS Catalysis

Catalyst Control over Twofold and Higher-Order Stereogenicity by Atroposelective Arene Formation

(2021) Tanno A. Schmidt et al.   ACCOUNTS OF CHEMICAL RESEARCH

Chemo‐ and Enantioselective Insertion of Furyl Carbene into the N−H Bond of 2‐Pyridones

(2021) Kai Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereodivergent Synthesis of Enantioenriched 2,3-Disubstituted Dihydrobenzofurans via a One-Pot C–H Functionalization/Oxa-Michael Addition Cascade

(2021) Dong-Xing Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Distal Allylic/Benzylic C−H Functionalization of Silyl Ethers Using Donor/Acceptor Rhodium(II) Carbenes

(2020) Huw Davies et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium(III)-Catalyzed Asymmetric Access to Spirocycles through C−H Activation and Axial-to-Central Chirality Transfer

(2020) Lingheng Kong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ir-Catalyzed Atroposelective Desymmetrization of Heterobiaryls: Hydroarylation of Vinyl Ethers and Bicycloalkenes

(2020) Antonio Romero-Arenas et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective C–H functionalization of bicyclo[1.1.1]pentanes

(2020) Zachary J. Garlets et al.   Nature Catalysis

Organocatalytic Enantioselective Synthesis of Atropisomeric Aryl‐ p ‐Quinones: Platform Molecules for Diversity‐Oriented Synthesis of Biaryldiols

(2020) Ye‐Hui Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Michael Reaction Inspired Atroposelective Construction of Axially Chiral Biaryls

(2020) Shengyi Yan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Cross-Coupling for Axially Chiral Tetra-ortho-Substituted Biaryls and Asymmetric Synthesis of Gossypol

(2020) He Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Ni-Catalyzed Electrochemical Synthesis of Biaryl Atropisomers

(2020) Hui Qiu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Atroposelective Ring Opening of Cyclic Diaryliodonium Salts with Bulky Anilines Controlled by a Chiral Cobalt(III) Anion

(2020) Zhenhua Gu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium-Catalyzed Atroposelective Oxidative C–H/C–H Cross-Coupling Reaction of 1-Aryl Isoquinoline Derivatives with Electron-Rich Heteroarenes

(2020) Qiang Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Diols Activation via Cu/Borinic Acids Synergistic Catalysis in Atroposelective Ring‐Opening of Cyclic Diaryliodoniums

(2020) Zhenhua Gu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Enantioselective Intermolecular Benzylic C(sp3 )−H Amination

(2019) Ali Nasrallah et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Carbon-Carbon Bond Cleavage for Biaryl Atropisomers Synthesis

(2019) Ruixian Deng et al.   Chem

Switchable Smiles Rearrangement for Enantioselective O-Aryl Amination

(2019) Xihao Chang et al.   ORGANIC LETTERS

A Bulky Chiral N-Heterocyclic Carbene Palladium Catalyst Enables Highly Enantioselective Suzuki–Miyaura Cross-Coupling Reactions for the Synthesis of Biaryl Atropisomers

(2019) Di Shen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Construction of Axially Chiral Compounds via Asymmetric Organocatalysis

(2018) Yong-Bin Wang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Recent advances in transition-metal-catalyzed asymmetric reactions of diazo compounds with electron-rich (hetero-) arenes

(2018) Yi-Pan Li et al.   TETRAHEDRON LETTERS

Enantioselective palladium-catalyzed C–H functionalization of pyrroles using an axially chiral 2,2′-bipyridine ligand

(2018) Hong-Qiang Shen et al.   Organic Chemistry Frontiers

Access to P - and Axially Chiral Biaryl Phosphine Oxides by Enantioselective Cpx IrIII -Catalyzed C−H Arylations

(2018) Yun-Suk Jang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium-Catalyzed Regioselective N 2 -Alkylation of Benzotriazoles with Diazo Compounds/Enynones via a Nonclassical Pathway

(2018) Kai Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Design of catalysts for site-selective and enantioselective functionalization of non-activated primary C–H bonds

(2018) Kuangbiao Liao et al.   Nature Chemistry

Access to N-Substituted 2-Pyridones by Catalytic Intermolecular Dearomatization and 1,4-Acyl Transfer

(2018) Guangyang Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Site-selective and stereoselective functionalization of non-activated tertiary C–H bonds

(2017) Kuangbiao Liao et al.   NATURE

Organocatalytic asymmetric arylation of indoles enabled by azo groups

(2017) Liang-Wen Qi et al.   Nature Chemistry

Sequential Au(i)/chiral tertiary amine catalysis: a tandem C–H functionalization of anisoles or a thiophene/asymmetric Michael addition sequence to quaternary oxindoles

(2016) Zhong-Yan Cao et al.   CHEMICAL COMMUNICATIONS

Gold-catalyzed construction of two adjacent quaternary stereocenters via sequential C–H functionalization and aldol annulation

(2016) Zhunzhun Yu et al.   CHEMICAL COMMUNICATIONS

Copper-catalyzed enantioselective C–H functionalization of indoles with an axially chiral bipyridine ligand

(2016) Xiang Gao et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Double C–H Functionalization of Indoles via Three-Component Reactions/CuCl2-Catalyzed Aerobic Dehydrogenative Coupling for the Synthesis of Polyfunctional Cyclopenta[b]indoles

(2016) Liqin Jiang et al.   ACS Catalysis

Enantioselective Palladium-Catalyzed CH Functionalization of Indoles Using an Axially Chiral 2,2′-Bipyridine Ligand

(2015) Xiang Gao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Modern Organic Synthesis with α-Diazocarbonyl Compounds

(2015) Alan Ford et al.   CHEMICAL REVIEWS

Recent advances and new concepts for the synthesis of axially stereoenriched biaryls

(2015) J. Wencel-Delord et al.   CHEMICAL SOCIETY REVIEWS

Catalytic Asymmetric Arylation of α-Aryl-α-diazoacetates with Aniline Derivatives

(2015) Bin Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Asymmetric Functionalization of Aromatic CH Bonds by Electrophilic Trapping of Metal-Carbene-Induced Zwitterionic Intermediates

(2014) Shikun Jia et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Construction of Axial Chirality by Rhodium-Catalyzed Asymmetric Dehydrogenative Heck Coupling of Biaryl Compounds with Alkenes

(2014) Jun Zheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic enantioselective intramolecular cyclization of N-aryl diazoamides using a titanium–BINOLate complex

(2014) Takuya Hashimoto et al.   CHEMICAL COMMUNICATIONS

Role of Sterically Demanding Chiral Dirhodium Catalysts in Site-Selective C–H Functionalization of Activated Primary C–H Bonds

(2014) Changming Qin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Efficient Syntheses of Korupensamines A, B and Michellamine B by Asymmetric Suzuki-Miyaura Coupling Reactions

(2013) Guangqing Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly enantioselective trapping of zwitterionic intermediates by imines

(2012) Huang Qiu et al.   Nature Chemistry

Rh2(S-biTISP)2-Catalyzed Asymmetric Functionalization of Indoles and Pyrroles with Vinylcarbenoids

(2012) Yajing Lian et al.   ORGANIC LETTERS

Iron-Catalyzed CH Fuctionalization of Indoles

(2011) Yan Cai et al.   ADVANCED SYNTHESIS & CATALYSIS

Guiding principles for site selective and stereoselective intermolecular C–H functionalization by donor/acceptor rhodium carbenes

(2011) Huw M. L. Davies et al.   CHEMICAL SOCIETY REVIEWS

Rhodium(II)-Catalyzed Enantioselective C−H Functionalization of Indoles

(2011) Andrew DeAngelis et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Carbene Insertion into C−H Bonds

(2009) Michael P. Doyle et al.   CHEMICAL REVIEWS

Total synthesis of chiral biaryl natural products by asymmetric biaryl coupling

(2009) Marisa C. Kozlowski et al.   CHEMICAL SOCIETY REVIEWS

Coinage Metal Catalyzed C−H Bond Functionalization of Hydrocarbons

(2008) M. Mar Díaz-Requejo et al.   CHEMICAL REVIEWS