Perspective for Single Atom Nanozymes Based Sensors: Advanced Materials, Sensing Mechanism, Selectivity Regulation, and Applications

Biomimetic Design of Mitochondria‐Targeted Hybrid Nanozymes as Superoxide Scavengers

(2021) Yue Zhang et al.   ADVANCED MATERIALS

Layered double hydroxides as an efficient nanozyme for analytical applications

(2021) Abolghasem Jouyban et al.   MICROCHEMICAL JOURNAL

Cu2+-modified hollow carbon nanospheres: an unusual nanozyme with enhanced peroxidase-like activity

(2021) Junlun Zhu et al.   Microchimica Acta

Platinum-Doped Prussian Blue Nanozymes for Multiwavelength Bioimaging Guided Photothermal Therapy of Tumor and Anti-Inflammation

(2021) Zi-Hao Li et al.   ACS Nano

Stimuli‐Responsive Manganese Single‐Atom Nanozyme for Tumor Therapy via Integrated Cascade Reactions

(2021) Yang Zhu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

2D metal azolate framework as nanozyme for amperometric detection of glucose at physiological pH and alkaline medium

(2021) Muhammad Adeel et al.   Microchimica Acta

Metal-organic frameworks-derived bimetallic Nanozyme platform enhances cytotoxic effect of photodynamic therapy in hypoxic Cancer cells

(2021) Xiao Han et al.   MATERIALS & DESIGN

Facile Fabrication of a Novel Copper Nanozyme for Efficient Dye Degradation

(2021) Xin Geng et al.   ACS Omega

Fe3C-Assisted Single Atomic Fe Sites for Sensitive Electrochemical Biosensing

(2021) Xiaoqian Wei et al.   ANALYTICAL CHEMISTRY

Single‐Atom Pd Nanozyme for Ferroptosis‐Boosted Mild‐Temperature Photothermal Therapy

(2021) Mengyu Chang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Antioxidant nanozyme counteracts HIV‐1 by modulating intracellular redox potential

(2021) Shalini Singh et al.   EMBO Molecular Medicine

Synergistic effect enhances the peroxidase-like activity in platinum nanoparticle-supported metal—organic framework hybrid nanozymes for ultrasensitive detection of glucose

(2021) Jing Li et al.   Nano Research

In vivo activation of pH-responsive oxidase-like graphitic nanozymes for selective killing of Helicobacter pylori

(2021) Lufeng Zhang et al.   Nature Communications

Nanozyme Sensor Array Plus Solvent-Mediated Signal Amplification Strategy for Ultrasensitive Ratiometric Fluorescence Detection of Exosomal Proteins and Cancer Identification

(2021) Meng-Xian Liu et al.   ANALYTICAL CHEMISTRY

DNA-encoded bimetallic Au-Pt dumbbell nanozyme for high-performance detection and eradication of Escherichia coli O157:H7

(2021) Chang Lu et al.   BIOSENSORS & BIOELECTRONICS

Hemin-assisted synthesis of peroxidase-like Fe-N-C nanozymes for detection of ascorbic acid-generating bio-enzymes

(2021) Wendong Liu et al.   CHEMICAL ENGINEERING JOURNAL

Prussian Blue: A Nanozyme with Versatile Catalytic Properties

(2021) Joan Estelrich et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

NIR enhanced peroxidase-like activity of Au@CeO2 hybrid nanozyme by plasmon-induced hot electrons and photothermal effect for bacteria killing

(2021) Chuang Liu et al.   APPLIED CATALYSIS B-ENVIRONMENTAL

Self-assembly of mercury-ion recognizing CuS nanocrystals into 3D sponge-like aerogel towards superior mercury capturer with outstanding selectivity and efficiency

(2021) Jianrong Guo et al.   CHEMICAL ENGINEERING JOURNAL

A ratiometric fluorescent sensing of proanthocyanidins by MnO2 nanosheets simultaneously tuning the photoluminescence of Au/AgNCs and thiamine

(2021) Yue Hu et al.   TALANTA

Single-Atom Enzyme-Functionalized Solution-Gated Graphene Transistor for Real-Time Detection of Mercury Ion

(2020) Lili Yao et al.   ACS Applied Materials & Interfaces

Electrodeposition-assisted Rapid Preparation of Pt Nanocluster/3D Graphene Hybrid Nanozyme with Outstanding Multiple Oxidase-Like Activity for Distinguishing Colorimetric Determination of Dihydroxybenzene Isomers

(2020) Na Qiu et al.   ACS Applied Materials & Interfaces

Cascade Reaction System Integrating Single-Atom Nanozymes with Abundant Cu Sites for Enhanced Biosensing

(2020) Yu Wu et al.   ANALYTICAL CHEMISTRY

An Enzyme-Mimicking Single-Atom Catalyst as an Efficient Multiple Reactive Oxygen and Nitrogen Species Scavenger for Sepsis Management

(2020) Fangfang Cao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Fe–N–C oxidase-like nanozyme used for catalytic oxidation of NOM in surface water

(2020) Hankun Yang et al.   WATER RESEARCH

Plasma-Assisted Controllable Doping of Nitrogen into MoS2 Nanosheets as Efficient Nanozymes with Enhanced Peroxidase-Like Catalysis Activity

(2020) Luping Feng et al.   ACS Applied Materials & Interfaces

Peroxidase‐Like Nanozymes Induce a Novel Form of Cell Death and Inhibit Tumor Growth In Vivo

(2020) Peixia Wang et al.   ADVANCED FUNCTIONAL MATERIALS

Co Single‐Atom Catalysts Boost Chemiluminescence

(2020) Hui Ouyang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Densely Isolated FeN4 Sites for Peroxidase Mimicking

(2020) Lei Jiao et al.   ACS Catalysis

Self-limited Phosphatase-mimicking CeO2 Nanozymes

(2020) Haiyan Liu et al.   ChemNanoMat

Single-atom iron containing nanozyme with peroxidase-like activity and copper nanoclusters based ratio fluorescent strategy for acetylcholinesterase activity sensing

(2020) Mengke Wang et al.   SENSORS AND ACTUATORS B-CHEMICAL

Single Iron Site Nanozyme for Ultrasensitive Glucose Detection

(2020) Min Chen et al.   Small

Single-atom platinum nanocatalyst-improved catalytic efficiency with enzyme-DNA supermolecular architectures

(2020) Ruijin Zeng et al.   Nano Energy

Metal‐Nitrogen‐Doped Carbon Materials as Highly Efficient Catalysts: Progress and Rational Design

(2020) Zhangsheng Shi et al.   Advanced Science

Single-atom doping of MoS2 with manganese enables ultrasensitive detection of dopamine: Experimental and computational approach

(2020) Yu Lei et al.   Science Advances

Peroxidase-like activity of Fe–N–C single-atom nanozyme based colorimetric detection of galactose

(2020) Xiaobin Zhou et al.   ANALYTICA CHIMICA ACTA

Ferric Ion Driven Assembly of Catalase‐like Supramolecular Photosensitizing Nanozymes for Combating Hypoxic Tumors

(2020) Yongxin Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cerium vanadate nanozyme with specific superoxide dismutase activity regulates mitochondrial function and ATP synthesis in neuronal cells

(2020) Namrata Singh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recoverable peroxidase-like Fe3O4@MoS2-Ag nanozyme with enhanced antibacterial ability

(2020) Feng Wei et al.   CHEMICAL ENGINEERING JOURNAL

Advances in Single‐Atom Nanozymes Research

(2020) Bing Jiang et al.   CHINESE JOURNAL OF CHEMISTRY

Single-atom nanozymes: A rising star for biosensing and biomedicine

(2020) Xianlong Zhang et al.   COORDINATION CHEMISTRY REVIEWS

Single-Atom Co–N4 Electrocatalyst Enabling Four-Electron Oxygen Reduction with Enhanced Hydrogen Peroxide Tolerance for Selective Sensing

(2020) Fei Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Self-Assembled Pd12 Coordination Cage as Photoregulated Oxidase-Like Nanozyme

(2020) Soumalya Bhattacharyya et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Single-Atom Nanozymes Linked Immunosorbent Assay for Sensitive Detection of Aβ 1-40: A Biomarker of Alzheimer’s Disease

(2020) Zhaoyuan Lyu et al.   Research

Perspectives for Single-Atom Nanozymes: Advanced Synthesis, Functional Mechanisms, and Biomedical Applications

(2020) Lihua Shen et al.   ANALYTICAL CHEMISTRY

Boron-doped Fe-N-C single-atom nanozymes specifically boost peroxidase-like activity

(2020) Lei Jiao et al.   Nano Today

Coordination Number Regulation of Molybdenum Single-Atom Nanozyme Peroxidase-like Specificity

(2020) Ying Wang et al.   Chem

Single-atom nanozyme enabled fast and highly sensitive colorimetric detection of Cr(VI)

(2020) Yu Mao et al.   JOURNAL OF HAZARDOUS MATERIALS

Enhanced Peroxidase Mimetic Activity of Porous Iron Oxide Nanoflakes

(2019) Shunsuke Tanaka et al.   ChemNanoMat

Nanocrystals: An Overview of Fabrication, Characterization and Therapeutic Applications in Drug Delivery

(2019) Vishwas P. Pardhi et al.   CURRENT PHARMACEUTICAL DESIGN

Avoiding Pre-Isolation Step in Exosome Analysis: Direct Isolation and Sensitive Detection of Exosomes Using Gold-Loaded Nanoporous Ferric Oxide Nanozymes

(2019) Kseniia Boriachek et al.   ANALYTICAL CHEMISTRY

Single‐Atom Nanozyme Based on Nanoengineered Fe–N–C Catalyst with Superior Peroxidase‐Like Activity for Ultrasensitive Bioassays

(2019) Nan Cheng et al.   Small

Single-atom nanozymes

(2019) Liang Huang et al.   Science Advances

Ultrasensitive Immunosensor for Cardiac Troponin I Detection Based on the Electrochemiluminescence of 2D Ru-MOF Nanosheets

(2019) Mengxia Yan et al.   ANALYTICAL CHEMISTRY

Fluorescent Graphitic Carbon Nitride-Based Nanozymes with Peroxidase-like Activities for Ratiometric Biosensing

(2019) Xiaoyu Wang et al.   ANALYTICAL CHEMISTRY

Fe–N–C Single-Atom Nanozymes for the Intracellular Hydrogen Peroxide Detection

(2019) Lei Jiao et al.   ANALYTICAL CHEMISTRY

Oxidase‐Like Fe‐N‐C Single‐Atom Nanozymes for the Detection of Acetylcholinesterase Activity

(2019) Yu Wu et al.   Small

Heme Cofactor‐Resembling Fe–N Single Site Embedded Graphene as Nanozymes to Selectively Detect H 2 O 2 with High Sensitivity

(2019) Min Su Kim et al.   ADVANCED FUNCTIONAL MATERIALS

A Nanozyme with Photo-Enhanced Dual Enzyme-Like Activities for Deep Pancreatic Cancer Therapy

(2019) Shanshan Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Unprecedented peroxidase-mimicking activity of single-atom nanozyme with atomically dispersed Fe–Nx moieties hosted by MOF derived porous carbon

(2019) Xiangheng Niu et al.   BIOSENSORS & BIOELECTRONICS

Copper/Carbon Hybrid Nanozyme: Tuning Catalytic Activity by the Copper State for Antibacterial Therapy

(2019) Juqun Xi et al.   NANO LETTERS

Single-atom electrocatalysis: a new approach to in vivo electrochemical biosensing

(2019) Hanfeng Hou et al.   Science China-Chemistry

Revealing the Intrinsic Peroxidase-Like Catalytic Mechanism of Heterogeneous Single-Atom Co–MoS2

(2019) Ying Wang et al.   Nano-Micro Letters

Promoting Active Sites in MOF-Derived Homobimetallic Hollow Nanocages as a High-Performance Multifunctional Nanozyme Catalyst for Biosensing and Organic Pollutant Degradation

(2019) Siqi Li et al.   ACS Applied Materials & Interfaces

One-pot bottom-up fabrication of a 2D/2D heterojuncted nanozyme towards optimized peroxidase-like activity for sulfide ions sensing

(2019) Xinnan Liu et al.   SENSORS AND ACTUATORS B-CHEMICAL

Size-controllable Fe-N/C single-atom nanozyme with exceptional oxidase-like activity for sensitive detection of alkaline phosphatase

(2019) Qiumeng Chen et al.   SENSORS AND ACTUATORS B-CHEMICAL

Ceria Nanoparticle Systems for Selective Scavenging of Mitochondrial, Intracellular, and Extracellular Reactive Oxygen Species in Parkinson's Disease

(2018) Hyek Jin Kwon et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nanozyme: An emerging alternative to natural enzyme for biosensing and immunoassay

(2018) Qingqing Wang et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Porous nanozymes: the peroxidase-mimetic activity of mesoporous iron oxide for the colorimetric and electrochemical detection of global DNA methylation

(2018) Ripon Bhattacharjee et al.   Journal of Materials Chemistry B

Unusual switchable peroxidase-mimicking nanozyme for the determination of proteolytic biomarker

(2018) Claire McVey et al.   Nano Research

Direct Electron Transfer of Enzymes Facilitated by Cytochromes

(2018) Su Ma et al.   ChemElectroChem

Molecular Imprinting on Inorganic Nanozymes for Hundred-fold Enzyme Specificity

(2017) Zijie Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Characterization of a selenocysteine-ligated P450 compound I reveals direct link between electron donation and reactivity

(2017) Elizabeth L. Onderko et al.   Nature Chemistry

Investigation of Horseradish Peroxidase Kinetics in an “Organelle-Like” Environment

(2017) Patric Baumann et al.   Small

Nanomaterials as nanocarriers: a critical assessment why these are multi-chore vanquisher in breast cancer treatment

(2017) Sania Naz et al.   Artificial Cells Nanomedicine and Biotechnology

Nanozymes: an emerging field bridging nanotechnology and biology

(2016) Lizeng Gao et al.   Science China-Life Sciences

Novel hierarchical NiO nanoflowers exhibiting intrinsic superoxide dismutase-like activity

(2016) Jianshuai Mu et al.   Journal of Materials Chemistry B

Nanozymes in bionanotechnology: from sensing to therapeutics and beyond

(2016) Xiaoyu Wang et al.   Inorganic Chemistry Frontiers

Catalytically Active Nanomaterials: A Promising Candidate for Artificial Enzymes

(2014) Youhui Lin et al.   ACCOUNTS OF CHEMICAL RESEARCH

Enzyme and coenzyme reaction mechanisms: Editorial overview

(2014) John P. Richard   BIOORGANIC CHEMISTRY

Origin of the Electrocatalytic Oxygen Reduction Activity of Graphene-Based Catalysts: A Roadmap to Achieve the Best Performance

(2014) Yan Jiao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An antioxidant nanozyme that uncovers the cytoprotective potential of vanadia nanowires

(2014) Amit A. Vernekar et al.   Nature Communications

Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes

(2013) Hui Wei et al.   CHEMICAL SOCIETY REVIEWS

The superfamily of heme–copper oxygen reductases: Types and evolutionary considerations

(2011) Filipa L. Sousa et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Single-atom catalysis of CO oxidation using Pt1/FeO x

(2011) Botao Qiao et al.   Nature Chemistry

Design principles for oxygen-reduction activity on perovskite oxide catalysts for fuel cells and metal–air batteries

(2011) Jin Suntivich et al.   Nature Chemistry

Superfamilies SDR and MDR: From early ancestry to present forms. Emergence of three lines, a Zn-metalloenzyme, and distinct variabilities

(2010) Hans Jörnvall et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Nanoceria exhibit redox state-dependent catalase mimetic activity

(2010) Talib Pirmohamed et al.   CHEMICAL COMMUNICATIONS