An Edaravone-Guided Design of a Rhodamine-Based Turn-on Fluorescent Probe for Detecting Hydroxyl Radicals in Living Systems

High‐Contrast Fluorescence Diagnosis of Cancer Cells/Tissues Based on β‐Lapachone‐Triggered ROS Amplification Specific in Cancer Cells

(2021) Jing Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Quantitative Design of Bright Fluorophores and AIEgens by the Accurate Prediction of Twisted Intramolecular Charge Transfer (TICT)

(2020) Chao Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemical reactivity and uses of 1-phenyl-3-methyl-5-pyrazolone (PMP), also known as edaravone

(2020) Christian Bailly et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Molecular Origins of Heteroatom Engineering on the Emission Wavelength Tuning, Quantum Yield Variations and Fluorogenicity of NBD‐like SCOTfluors

(2020) Ying Gao et al.   Chemistry-An Asian Journal

Fluorescent detectors for hydroxyl radical and their applications in bioimaging: A review

(2020) Ji-Ting Hou et al.   COORDINATION CHEMISTRY REVIEWS

A comprehensive review on β-lapachone: Mechanisms, structural modifications, and therapeutic potentials

(2020) Qijie Gong et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Illuminating the Function of the Hydroxyl Radical in the Brains of Mice with Depression Phenotypes by Two-Photon Fluorescence Imaging

(2019) Xin Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Quaternary Piperazine-Substituted Rhodamines with Enhanced Brightness for Super-Resolution Imaging

(2019) Zhiwei Ye et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Lighting Up NIR-II Fluorescence in Vivo: An Activable Probe for Noninvasive Hydroxyl Radical Imaging

(2019) Wenqi Feng et al.   ANALYTICAL CHEMISTRY

Ferroptosis Accompanied by •OH Generation and Cytoplasmic Viscosity Increase Revealed via Dual-Functional Fluorescence Probe

(2019) Hongyu Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Near infrared dye-conjugated oxidative stress amplifying polymer micelles for dual imaging and synergistic anticancer phototherapy

(2018) Wonseok Yang et al.   BIOMATERIALS

Dose-dependency of multiple free radical-scavenging activity of edaravone

(2018) Osamu Tokumaru et al.   JOURNAL OF SURGICAL RESEARCH

Rationally Designed Fluorescence . OH Probe with High Sensitivity and Selectivity for Monitoring the Generation of . OH in Iron Autoxidation without Addition of H2 O2

(2018) Hongyu Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Discovery of Nonquinone Substrates for NAD(P)H: Quinone Oxidoreductase 1 (NQO1) as Effective Intracellular ROS Generators for the Treatment of Drug-Resistant Non-Small-Cell Lung Cancer

(2018) Xingsen Wu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Edaravone and its clinical development for amyotrophic lateral sclerosis

(2017) Koji Takei et al.   Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Real-Time Discrimination and Versatile Profiling of Spontaneous Reactive Oxygen Species in Living Organisms with a Single Fluorescent Probe

(2016) Ruilong Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Role of labile iron in the toxicity of pharmacological ascorbate

(2015) Juan Du et al.   FREE RADICAL BIOLOGY AND MEDICINE

A general method to improve fluorophores for live-cell and single-molecule microscopy

(2015) Jonathan B Grimm et al.   NATURE METHODS

Modulation of oxidative stress as an anticancer strategy

(2013) Chiara Gorrini et al.   NATURE REVIEWS DRUG DISCOVERY

On the•OH and•OOH scavenging activity of 3-methyl-1-pyridin-2-yl-5-pyrazolone: Comparisons with its parent compound, edaravone

(2012) Adriana Pérez-González et al.   INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY

Reactive oxygen species, cellular redox systems, and apoptosis

(2010) Magdalena L. Circu et al.   FREE RADICAL BIOLOGY AND MEDICINE

OH Radical Scavenging Activity of Edaravone: Mechanism and Kinetics

(2010) Adriana Pérez-González et al.   JOURNAL OF PHYSICAL CHEMISTRY B

HKGreen-3: A Rhodol-Based Fluorescent Probe for Peroxynitrite

(2010) Tao Peng et al.   ORGANIC LETTERS

Edaravone, a Free Radical Scavenger, Protects against Retinal Damage in Vitro and in Vivo

(2009) Y. Inokuchi et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The Novel Antioxidant Edaravone: From Bench to Bedside

(2008) Toshiaki Watanabe et al.   Cardiovascular Therapeutics