Reincarnation of the Analytical Ultracentrifuge: Emerging Opportunities for Nanomedicine

Nanotechnology for Modern Medicine: Next Steps Towards Clinical Translation

(2021) Shrey Sindhwani et al.   JOURNAL OF INTERNAL MEDICINE

Pfizer's vaccine raises allergy concerns

(2021) Jop de Vrieze   SCIENCE

Density Matching Multi-wavelength Analytical Ultracentrifugation to Measure Drug Loading of Lipid Nanoparticle Formulations

(2021) Amy Henrickson et al.   ACS Nano

Polyglycerol for Half-Life Extension of Proteins—Alternative to PEGylation?

(2021) Michael Tully et al.   BIOMACROMOLECULES

The dawn of mRNA vaccines: The COVID-19 case

(2021) Rein Verbeke et al.   JOURNAL OF CONTROLLED RELEASE

Stealth Effect of Short Polyoxazolines in Graft Copolymers: Minor Changes of Backbone End Group Determine Liver Cell-Type Specificity

(2021) Irina Muljajew et al.   ACS Nano

Analytical band centrifugation for the separation and quantification of empty and full AAV particles

(2021) Harshit Khasa et al.   Molecular Therapy-Methods & Clinical Development

Incentives of Using the Hydrodynamic Invariant and Sedimentation Parameter for the Study of Naturally- and Synthetically-Based Macromolecules in Solution

(2020) Mandy Grube et al.   Polymers

In Situ, Quantitative Assessment of Multifunctional Nanoscale Drug Delivery Systems in Human Serum

(2020) Gizem Cinar et al.   ANALYTICAL CHEMISTRY

Analytical ultracentrifugation for measuring drug distribution of doxorubicin loaded liposomes in human serum

(2020) Dora Mehn et al.   JOURNAL OF NANOPARTICLE RESEARCH

Moving analytical ultracentrifugation software to a good manufacturing practices (GMP) environment

(2020) Alexey Savelyev et al.   PLoS Computational Biology

Polysaccharide valproates: Structure - property relationships in solution

(2020) Mandy Grube et al.   CARBOHYDRATE POLYMERS

Unraveling Decisive Structural Parameters for the Self-Assembly of Supramolecular Polymer Bottlebrushes Based on Benzene Trisureas

(2020) Franka V. Gruschwitz et al.   MACROMOLECULES

Measuring compressibility in the optima AUC™ analytical ultracentrifuge

(2020) Marielle Stoutjesdyk et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Solely aqueous formulation of hydrophobic cationic polymers for efficient gene delivery

(2020) Jana I. Solomun et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Overcoming the Necessity of a Lateral Aggregation in the Formation of Supramolecular Polymer Bottlebrushes in Water

(2020) Tobias Klein et al.   MACROMOLECULAR RAPID COMMUNICATIONS

Engineering precision nanoparticles for drug delivery

(2020) Michael J. Mitchell et al.   NATURE REVIEWS DRUG DISCOVERY

Measuring particle size distribution of nanoparticle enabled medicinal products, the joint view of EUNCL and NCI-NCL. A step by step approach combining orthogonal measurements with increasing complexity

(2019) F. Caputo et al.   JOURNAL OF CONTROLLED RELEASE

Bridging communities in the field of nanomedicine

(2019) Blanka Halamoda-Kenzaoui et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Revisiting very disperse macromolecule populations in hydrodynamic and light scattering studies of sodium carboxymethyl celluloses

(2019) Mandy Grube et al.   CARBOHYDRATE POLYMERS

The influence of directed hydrogen bonds on the self-assembly of amphiphilic polymers in water

(2019) Tobias Klein et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Multi-speed sedimentation velocity implementation in UltraScan-III

(2018) Gary E. Gorbet et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Analytical band centrifugation revisited

(2018) Cornelia M. Schneider et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

AUC measurements of diffusion coefficients of monoclonal antibodies in the presence of human serum proteins

(2018) Robert T. Wright et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

POx as an Alternative to PEG? A Hydrodynamic and Light Scattering Study

(2018) Mandy Grube et al.   MACROMOLECULES

Conformational properties of biocompatible poly(2-ethyl-2-oxazoline)s in phosphate buffered saline

(2018) Alexander S. Gubarev et al.   Polymer Chemistry

PMMA-g-OEtOx Graft Copolymers: Influence of Grafting Degree and Side Chain Length on the Conformation in Aqueous Solution

(2018) Irina Muljajew et al.   Materials

Band Sedimentation Experiment in Analytical Ultracentrifugation Revisited

(2018) Cornelia M. Schneider et al.   ANALYTICAL CHEMISTRY

Nano based drug delivery systems: recent developments and future prospects

(2018) Jayanta Kumar Patra et al.   JOURNAL OF NANOBIOTECHNOLOGY

Nanoparticles as carriers of proteins, peptides and other therapeutic molecules

(2018) Agnieszka Pudlarz et al.   Open Life Sciences

Analytical ultracentrifugation for analysis of doxorubicin loaded liposomes

(2017) Dora Mehn et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Site-Specific POxylation of Interleukin-4

(2017) Tessa Lühmann et al.   ACS Biomaterials-Science & Engineering

Site-Specific POxylation of Interleukin-4

(2017) Tessa Lühmann et al.   ACS Biomaterials Science & Engineering

Hydrodynamic Analysis Resolves the Pharmaceutically-Relevant Absolute Molar Mass and Solution Properties of Synthetic Poly(ethylene glycol)s Created by Varying Initiation Sites

(2016) Ivo Nischang et al.   ANALYTICAL CHEMISTRY

Simultaneous Identification of Spectral Properties and Sizes of Multiple Particles in Solution with Subnanometer Resolution

(2016) Engin Karabudak et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dynamic range multiwavelength particle characterization using analytical ultracentrifugation

(2016) Johannes Walter et al.   Nanoscale

A Multilaboratory Comparison of Calibration Accuracy and the Performance of External References in Analytical Ultracentrifugation

(2015) Huaying Zhao et al.   PLoS One

Multidimensional Analysis of Nanoparticles with Highly Disperse Properties Using Multiwavelength Analytical Ultracentrifugation

(2014) Johannes Walter et al.   ACS Nano

Nanomedicines: addressing the scientific and regulatory gap

(2014) Sally Tinkle et al.   Annals of the New York Academy of Sciences

Non-viral vectors for gene-based therapy

(2014) Hao Yin et al.   NATURE REVIEWS GENETICS

Effect of PEGylation on Protein Hydrodynamics

(2012) Yatin R. Gokarn et al.   MOLECULAR PHARMACEUTICS

Poly(ethylene glycol) in Drug Delivery: Pros and Cons as Well as Potential Alternatives

(2010) Katrin Knop et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Open AUC Project

(2009) Helmut Cölfen et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Effect of PEGylation on the Solution Conformation of Antibody Fragments

(2007) Yanling Lu et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Modern analytical ultracentrifugation in protein science: A tutorial review

(2002) Jacob Lebowitz et al.   PROTEIN SCIENCE