Enhancing mask activity in dopaminergic neurons extends lifespan in flies

Serotonin 2A receptor signaling coordinates central metabolic processes to modulate aging in response to nutrient choice

(2021) Yang Lyu et al.   eLife

Mask, the Drosophila Ankyrin Repeat and KH domain-containing protein, affects microtubule stability

(2021) Daniel Martinez et al.   JOURNAL OF CELL SCIENCE

Divergent Nodes of Non-autonomous UPRER Signaling through Serotonergic and Dopaminergic Neurons

(2020) Ryo Higuchi-Sanabria et al.   Cell Reports

Sensory perception of dead conspecifics induces aversive cues and modulates lifespan through serotonin in Drosophila

(2019) Tuhin S. Chakraborty et al.   Nature Communications

Nitric oxide acts as a cotransmitter in a subset of dopaminergic neurons to diversify memory dynamics

(2019) Yoshinori Aso et al.   eLife

Brain–gut communications via distinct neuroendocrine signals bidirectionally regulate longevity inC. elegans

(2018) Bi Zhang et al.   GENES & DEVELOPMENT

Drosophila mushroom bodies integrate hunger and satiety signals to control innate food-seeking behavior

(2018) Chang-Hui Tsao et al.   eLife

The Mitochondrial Unfolded Protein Response Is Mediated Cell-Non-autonomously by Retromer-Dependent Wnt Signaling

(2018) Qian Zhang et al.   CELL

Hypothalamic stem cells control ageing speed partly through exosomal miRNAs

(2017) Yalin Zhang et al.   NATURE

Neuronal Depolarization Drives Increased Dopamine Synaptic Vesicle Loading via VGLUT

(2017) Jenny I. Aguilar et al.   NEURON

A small-molecule activator of kinesin-1 drives remodeling of the microtubule network

(2017) Thomas S. Randall et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Branch-specific plasticity of a bifunctional dopamine circuit encodes protein hunger

(2017) Qili Liu et al.   SCIENCE

Survival and Causes of Death Among People With Clinically Diagnosed Synucleinopathies With Parkinsonism

(2017) Rodolfo Savica et al.   JAMA Neurology

The CApillary FEeder Assay Measures Food Intake in Drosophila melanogaster

(2017) Soeren Diegelmann et al.   Jove-Journal of Visualized Experiments

The Neuronal Kinesin UNC-104/KIF1A Is a Key Regulator of Synaptic Aging and Insulin Signaling-Regulated Memory

(2016) Ling-Bo Li et al.   CURRENT BIOLOGY

Stability properties of neuronal microtubules

(2016) Peter W. Baas et al.   Cytoskeleton

A C. elegans Thermosensory Circuit Regulates Longevity through crh-1 /CREB-Dependent flp-6 Neuropeptide Signaling

(2016) Yen-Chih Chen et al.   DEVELOPMENTAL CELL

Diversity matters - heterogeneity of dopaminergic neurons in the ventral mesencephalon and its relation to Parkinson's Disease

(2016) Daniela Maria Vogt Weisenhorn et al.   JOURNAL OF NEUROCHEMISTRY

FoxO1 in dopaminergic neurons regulates energy homeostasis and targets tyrosine hydroxylase

(2016) Khanh V. Doan et al.   Nature Communications

Serotonin signaling mediates protein valuation and aging

(2016) Jennifer Ro et al.   eLife

Mask loss-of-function rescues mitochondrial impairment and muscle degeneration of Drosophila pink1 and parkin mutants

(2015) Mingwei Zhu et al.   HUMAN MOLECULAR GENETICS

Shared neurocircuitry underlying feeding and drugs of abuse in Drosophila

(2015) Dan Landayan et al.   Biomedical Journal

Converging Circuits Mediate Temperature and Shock Aversive Olfactory Conditioning in Drosophila

(2014) Dana Shani Galili et al.   CURRENT BIOLOGY

Longevity Manipulations Differentially Affect Serotonin/Dopamine Level and Behavioral Deterioration in Aging Caenorhabditis elegans

(2014) J.-A. Yin et al.   JOURNAL OF NEUROSCIENCE

Hormonal and neural mechanisms of food reward, eating behaviour and obesity

(2014) Susan Murray et al.   Nature Reviews Endocrinology

Water sensor ppk28 modulates Drosophila lifespan and physiology through AKH signaling

(2014) M. J. Waterson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Critical Period of Sleep for Development of Courtship Circuitry and Behavior in Drosophila

(2014) M. S. Kayser et al.   SCIENCE

Systemic regulation of mammalian ageing and longevity by brain sirtuins

(2014) Akiko Satoh et al.   Nature Communications

AMPK Modulates Tissue and Organismal Aging in a Non-Cell-Autonomous Manner

(2014) Matthew Ulgherait et al.   Cell Reports

Mask Is Required for the Activity of the Hippo Pathway Effector Yki/YAP

(2013) Leticia Sansores-Garcia et al.   CURRENT BIOLOGY

Mask Proteins Are Cofactors of Yorkie/YAP in the Hippo Pathway

(2013) Clara M. Sidor et al.   CURRENT BIOLOGY

Selective degeneration of dopaminergic neurons by MPP+and its rescue by D2 autoreceptors inDrosophilaprimary culture

(2013) Lyle Wiemerslage et al.   JOURNAL OF NEUROCHEMISTRY

Hypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRH

(2013) Guo Zhang et al.   NATURE

Drosophila Life Span and Physiology Are Modulated by Sexual Perception and Reward

(2013) C. M. Gendron et al.   SCIENCE

DREADDs in Drosophila: A Pharmacogenetic Approach for Controlling Behavior, Neuronal Signaling, and Physiology in the Fly

(2013) Jaime Becnel et al.   Cell Reports

Dynactin Subunit p150Glued Is a Neuron-Specific Anti-Catastrophe Factor

(2013) Jacob E. Lazarus et al.   PLOS BIOLOGY

Two Dopaminergic Neurons Signal to the Dorsal Fan-Shaped Body to Promote Wakefulness in Drosophila

(2012) Qili Liu et al.   CURRENT BIOLOGY

Layered reward signalling through octopamine and dopamine in Drosophila

(2012) Christopher J. Burke et al.   NATURE

Dopaminergic Modulation of Sucrose Acceptance Behavior in Drosophila

(2012) Sunanda Marella et al.   NEURON

KH domains with impaired nucleic acid binding as a tool for functional analysis

(2012) David Hollingworth et al.   NUCLEIC ACIDS RESEARCH

Genetic coregulation of age of female sexual maturation and lifespan through circulating IGF1 among inbred mouse strains

(2012) R. Yuan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DILP-producing median neurosecretory cells in the Drosophila brain mediate the response of lifespan to nutrition

(2010) Susan J. Broughton et al.   AGING CELL

Behavioral consequences of dopamine deficiency in the Drosophila central nervous system

(2010) T. Riemensperger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of the Longevity Response to Temperature by Thermosensory Neurons in Caenorhabditis elegans

(2009) Seung-Jae Lee et al.   CURRENT BIOLOGY

Metabolic hormones, dopamine circuits, and feeding

(2009) Nandakumar S. Narayanan et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Amino-acid imbalance explains extension of lifespan by dietary restriction in Drosophila

(2009) Richard C. Grandison et al.   NATURE

Eight different types of dopaminergic neurons innervate the Drosophila mushroom body neuropil: anatomical and physiological heterogeneity

(2009) Zhengmei Mao   Frontiers in Neural Circuits