Combating Complement's Deleterious Effects on Nanomedicine by Conjugating Complement Regulatory Proteins to Nanoparticles

Nanoparticle-Induced Complement Activation: Implications for Cancer Nanomedicine

(2021) Ninh M. La-Beck et al.   Frontiers in Immunology

Complement activation by drug carriers and particulate pharmaceuticals: Principles, challenges and opportunities

(2020) S. Moein Moghimi et al.   ADVANCED DRUG DELIVERY REVIEWS

Stealth Coating of Nanoparticles in Drug-Delivery Systems

(2020) See Yee Fam et al.   Nanomaterials

Cloaking Silica Nanoparticles with Functional Protein Coatings for Reduced Complement Activation and Cellular Uptake

(2020) Jae Hyeon Park et al.   ACS Nano

The story of complement factor I

(2019) Peter J Lachmann   IMMUNOBIOLOGY

Complement therapeutics meets nanomedicine: overcoming human complement activation and leukocyte uptake of nanomedicines with soluble domains of CD55

(2019) Geoffrey Gifford et al.   JOURNAL OF CONTROLLED RELEASE

The Interplay between Blood Proteins, Complement, and Macrophages on Nanomedicine Performance and Responses

(2019) Seyed Moein Moghimi et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Complement activation in vitro and reactogenicity of low-molecular weight dextran-coated SPIONs in the pig CARPA model: Correlation with physicochemical features and clinical information

(2018) Tamás Fülöp et al.   JOURNAL OF CONTROLLED RELEASE

PEGylation of model drug carriers enhances phagocytosis by primary human neutrophils

(2018) William J. Kelley et al.   Acta Biomaterialia

Animal models for analysis of immunological responses to nanomaterials: Challenges and considerations

(2018) William C. Zamboni et al.   ADVANCED DRUG DELIVERY REVIEWS

Vascular targeting of radiolabeled liposomes with bio-orthogonally conjugated ligands: single chain fragments provide higher specificity than antibodies.

(2018) Elizabeth D Hood et al.   BIOCONJUGATE CHEMISTRY

The Lung Microvasculature Is a Functional Immune Niche

(2018) Elise Granton et al.   TRENDS IN IMMUNOLOGY

Immunoglobulin deposition on biomolecule corona determines complement opsonization efficiency of preclinical and clinical nanoparticles

(2018) Vivian P. Vu et al.   Nature Nanotechnology

Mechanisms that determine nanocarrier targeting to healthy versus inflamed lung regions

(2017) Jacob S. Brenner et al.   Nanomedicine-Nanotechnology Biology and Medicine

The renaissance of complement therapeutics

(2017) Daniel Ricklin et al.   Nature Reviews Nephrology

Complement factor H in host defense and immune evasion

(2016) Raffaella Parente et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Complement component C3 - The “Swiss Army Knife” of innate immunity and host defense

(2016) Daniel Ricklin et al.   IMMUNOLOGICAL REVIEWS

Factor H inhibits complement activation induced by liposomal and micellar drugs and the therapeutic antibody rituximab in vitro

(2016) Tamás Mészáros et al.   Nanomedicine-Nanotechnology Biology and Medicine

Complement proteins bind to nanoparticle protein corona and undergo dynamic exchange in vivo

(2016) Fangfang Chen et al.   Nature Nanotechnology

Analysis of nanoparticle delivery to tumours

(2016) Stefan Wilhelm et al.   Nature Reviews Materials

Complement activation-related pseudoallergy: A stress reaction in blood triggered by nanomedicines and biologicals

(2014) Janos Szebeni   MOLECULAR IMMUNOLOGY

ICAM-1 Targeted Nanogels Loaded with Dexamethasone Alleviate Pulmonary Inflammation

(2014) M. Carme Coll Ferrer et al.   PLoS One

Pulmonary intravascular macrophages and lung health: What are we missing?

(2012) David Schneberger et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Nanoparticle Size and Surface Chemistry Determine Serum Protein Adsorption and Macrophage Uptake

(2011) Carl D. Walkey et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Complement factor I in health and disease

(2011) Sara C. Nilsson et al.   MOLECULAR IMMUNOLOGY