Therapeutic siCCR2 Loaded by Tetrahedral Framework DNA Nanorobotics in Therapy for Intracranial Hemorrhage

CCR2 deficiency in monocytes impairs angiogenesis and functional recovery after ischemic stroke in mice

(2020) Jordi Pedragosa et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

TREM2 activation attenuates neuroinflammation and neuronal apoptosis via PI3K/Akt pathway after intracerebral hemorrhage in mice

(2020) Shengpan Chen et al.   Journal of Neuroinflammation

CCR2 is localized in microglia and neurons, as well as infiltrating monocytes, in the lumbar spinal cord of ALS mice

(2020) Hiroyasu Komiya et al.   Molecular Brain

Design, fabrication and applications of tetrahedral DNA nanostructure-based multifunctional complexes in drug delivery and biomedical treatment

(2020) Tao Zhang et al.   Nature Protocols

Progress toward Understanding the Interactions between DNA Nanostructures and the Cell

(2019) Yee Ting Elaine Chiu et al.   Small

AAVcis-regulatory sequences are correlated with ocular toxicity

(2019) Wenjun Xiong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Intelligent DNA Nanorobot with in Vitro Enhanced Protein Lysosomal Degradation of HER2

(2019) Wenjuan Ma et al.   NANO LETTERS

Role of CCR2 in the Development of Streptozotocin-treated Diabetic Cardiomyopathy

(2019) Xin Tan et al.   DIABETES

Enhanced Efficacy of Temozolomide Loaded by a Tetrahedral Framework DNA Nanoparticle in the Therapy for Glioblastoma

(2019) Wei Fu et al.   ACS Applied Materials & Interfaces

Overcoming the Blood-Brain Barrier: The Role of Nanomaterials in Treating Neurological Diseases

(2018) Denzil Furtado et al.   ADVANCED MATERIALS

DNA Nanocarriers: Programmed to Deliver

(2018) Bharath Raj Madhanagopal et al.   TRENDS IN BIOCHEMICAL SCIENCES

TREM2 in Neurodegenerative Diseases

(2017) Taylor R. Jay et al.   Molecular Neurodegeneration

Modulators of microglial activation and polarization after intracerebral haemorrhage

(2017) Xi Lan et al.   Nature Reviews Neurology

CCL2/CCR2, but not CCL5/CCR5, mediates monocyte recruitment, inflammation and cartilage destruction in osteoarthritis

(2016) Harini Raghu et al.   ANNALS OF THE RHEUMATIC DISEASES

Microglial Polarization and Inflammatory Mediators After Intracerebral Hemorrhage

(2016) Zhen Zhang et al.   MOLECULAR NEUROBIOLOGY

Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models

(2016) Saravanan S. Karuppagounder et al.   Science Translational Medicine

DNA as Tunable Adaptor for siRNA Polyplex Stabilization and Functionalization

(2016) Philipp Heissig et al.   Molecular Therapy-Nucleic Acids

Microglia regulate blood clearance in subarachnoid hemorrhage by heme oxygenase-1

(2015) Nils Schallner et al.   JOURNAL OF CLINICAL INVESTIGATION

In vivo toxicity of cationic micelles and liposomes

(2015) Kristina Bram Knudsen et al.   Nanomedicine-Nanotechnology Biology and Medicine

Guidelines for the Management of Spontaneous Intracerebral Hemorrhage

(2015) J. Claude Hemphill et al.   STROKE

CCR2 defines in vivo development and homing of IL-23-driven GM-CSF-producing Th17 cells

(2015) Ervin E. Kara et al.   Nature Communications

Photoluminescent Mesoporous Silicon Nanoparticles with siCCR2 Improve the Effects of Mesenchymal Stromal Cell Transplantation after Acute Myocardial Infarction

(2015) Wenbin Lu et al.   Theranostics

Advances and Challenges of Liposome Assisted Drug Delivery

(2015) Lisa Sercombe et al.   Frontiers in Pharmacology

Silencing of CCR2 in myocarditis

(2014) Florian Leuschner et al.   EUROPEAN HEART JOURNAL

Role of CCR2 in Inflammatory Conditions of the Central Nervous System

(2014) Hannah X Chu et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

CD36-Mediated Hematoma Absorption following Intracerebral Hemorrhage: Negative Regulation by TLR4 Signaling

(2014) H. Fang et al.   JOURNAL OF IMMUNOLOGY

Cleaning up after ICH: the role of Nrf2 in modulating microglia function and hematoma clearance

(2014) Xiurong Zhao et al.   JOURNAL OF NEUROCHEMISTRY

Suppression of CXCL2 upregulation underlies the therapeutic effect of the retinoid Am80 on intracerebral hemorrhage in mice

(2014) Hideaki Matsushita et al.   JOURNAL OF NEUROSCIENCE RESEARCH

NF-κB activation and cell death after intracerebral hemorrhage in patients

(2014) Zeli Zhang et al.   NEUROLOGICAL SCIENCES

Neuroinflammation after intracerebral hemorrhage

(2014) Eva Mracsko et al.   Frontiers in Cellular Neuroscience

Hemoglobin-Induced Nitric Oxide Synthase Overexpression and Nitric Oxide Production Contribute to Blood–Brain Barrier Disruption in the Rat

(2013) Shuo Yang et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Early surgery versus initial conservative treatment in patients with spontaneous supratentorial lobar intracerebral haematomas (STICH II): a randomised trial

(2013) A David Mendelow et al.   LANCET

Inflammation in intracerebral hemorrhage: From mechanisms to clinical translation

(2013) Yu Zhou et al.   PROGRESS IN NEUROBIOLOGY

The CCL2-CCR2 system affects the progression and clearance of intracerebral hemorrhage

(2012) Yao Yao et al.   GLIA

Intracerebral haemorrhage: mechanisms of injury and therapeutic targets

(2012) Richard F Keep et al.   LANCET NEUROLOGY

Toll-like receptor 4 contributes to poor outcome after intracerebral hemorrhage

(2011) Lauren H. Sansing et al.   ANNALS OF NEUROLOGY

Regulation and Functions of the IL-10 Family of Cytokines in Inflammation and Disease

(2011) Wenjun Ouyang et al.   Annual Review of Immunology

Preclinical and clinical research on inflammation after intracerebral hemorrhage

(2010) Jian Wang   PROGRESS IN NEUROBIOLOGY

Effects of Deferoxamine on Intracerebral Hemorrhage-Induced Brain Injury in Aged Rats

(2009) Masanobu Okauchi et al.   STROKE

Management of intracerebral hemorrhage

(2008) Mahmut Edip Gurol et al.   Current Atherosclerosis Reports