Mapping Sphingolipid Metabolism Pathways during Phagosomal Maturation

A Superfamily-wide Activity Atlas of Serine Hydrolases in Drosophila melanogaster

(2021) Kundan Kumar et al.   BIOCHEMISTRY

A chemical–genetic screen identifies ABHD12 as an oxidized-phosphatidylserine lipase

(2019) Dhanashree S. Kelkar et al.   Nature Chemical Biology

Mechanism of glucocerebrosidase activation and dysfunction in Gaucher disease unraveled by molecular dynamics and deep learning

(2019) Raquel Romero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GBA1-associated parkinsonism

(2019) Emory Ryan et al.   CURRENT OPINION IN NEUROLOGY

Glucocerebrosidase and its relevance to Parkinson disease

(2019) Jenny Do et al.   Molecular Neurodegeneration

Role of Ceramidases in Sphingolipid Metabolism and Human Diseases

(2019) Farzana Parveen et al.   Cells

Lipidomics Suggests a New Role for Ceramide Synthase in Phagocytosis

(2018) Divya Pathak et al.   ACS Chemical Biology

The role of glucocerebrosidase in Parkinson disease pathogenesis

(2018) Matthew E. Gegg et al.   FEBS Journal

Development of a Label-Free LC-MS/MS-Based Glucosylceramide Synthase Assay and Its Application to Inhibitors Screening for Ceramide-Related Diseases

(2018) Zhicheng Fu et al.   Biomolecules & Therapeutics

Drosophila DNA/RNA methyltransferase contributes to robust host defense in ageing animals by regulating sphingolipid metabolism

(2018) Varada Abhyankar et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

The Human Plasma Proteome Draft of 2017: Building on the Human Plasma PeptideAtlas from Mass Spectrometry and Complementary Assays

(2017) Jochen M. Schwenk et al.   JOURNAL OF PROTEOME RESEARCH

The metabolism of glucocerebrosides — From 1965 to the present

(2017) Anthony H. Futerman et al.   MOLECULAR GENETICS AND METABOLISM

Patterns, Receptors, and Signals: Regulation of Phagosome Maturation

(2017) Anne-Marie Pauwels et al.   TRENDS IN IMMUNOLOGY

Ceramide Signaling and Metabolism in Pathophysiological States of the Lung

(2016) Irina Petrache et al.   Annual Review of Physiology

Human SRMAtlas: A Resource of Targeted Assays to Quantify the Complete Human Proteome

(2016) Ulrike Kusebauch et al.   CELL

Dynein Clusters into Lipid Microdomains on Phagosomes to Drive Rapid Transport toward Lysosomes

(2016) Ashim Rai et al.   CELL

The life cycle of phagosomes: formation, maturation, and resolution

(2016) Roni Levin et al.   IMMUNOLOGICAL REVIEWS

Dihydroceramide desaturase 1, the gatekeeper of ceramide induced lipotoxicity

(2015) S. Rodriguez-Cuenca et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

High-resolution quantitative proteome analysis reveals substantial differences between phagosomes of RAW 264.7 and bone marrow derived macrophages

(2015) Manman Guo et al.   PROTEOMICS

Targeted Peptide Measurements in Biology and Medicine: Best Practices for Mass Spectrometry-based Assay Development Using a Fit-for-Purpose Approach

(2014) Steven A. Carr et al.   MOLECULAR & CELLULAR PROTEOMICS

Loss of Function of Glucocerebrosidase GBA2 Is Responsible for Motor Neuron Defects in Hereditary Spastic Paraplegia

(2013) Elodie Martin et al.   AMERICAN JOURNAL OF HUMAN GENETICS

New insights on glucosylated lipids: Metabolism and functions

(2013) Yohei Ishibashi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Ceramide synthases at the centre of sphingolipid metabolism and biology

(2012) Thomas D. Mullen et al.   BIOCHEMICAL JOURNAL

Selected reaction monitoring–based proteomics: workflows, potential, pitfalls and future directions

(2012) Paola Picotti et al.   NATURE METHODS

The Cell Biology of Phagocytosis

(2011) Ronald S. Flannagan et al.   Annual Review of Pathology-Mechanisms of Disease

Ceramides as modulators of cellular and whole-body metabolism

(2011) Benjamin T. Bikman et al.   JOURNAL OF CLINICAL INVESTIGATION

Dihydroceramide desaturase and dihydrosphingolipids: Debutant players in the sphingolipid arena

(2011) Gemma Fabrias et al.   PROGRESS IN LIPID RESEARCH

Hyperacidification of Trans-Golgi Network and Endo/Lysosomes in Melanocytes by Glucosylceramide-Dependent V-ATPase Activity

(2011) Seléne van der Poel et al.   TRAFFIC

Skyline: an open source document editor for creating and analyzing targeted proteomics experiments

(2010) Brendan MacLean et al.   BIOINFORMATICS

A simple fluorogenic method for determination of acid ceramidase activity and diagnosis of Farber disease

(2010) Carmen Bedia et al.   JOURNAL OF LIPID RESEARCH

Molecular characterization of the evolution of phagosomes

(2010) Jonathan Boulais et al.   Molecular Systems Biology

Ceramide-enriched membrane domains—Structure and function

(2008) Yang Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The sphingolipid salvage pathway in ceramide metabolism and signaling

(2008) Kazuyuki Kitatani et al.   CELLULAR SIGNALLING

Pathogen destruction versus intracellular survival: the role of lipids as phagosomal fate determinants

(2008) Benjamin E. Steinberg et al.   JOURNAL OF CLINICAL INVESTIGATION

Phagosome maturation: going through the acid test

(2008) Jason M. Kinchen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY