Current strategies of mechanical stimulation for maturation of cardiac microtissues

Mechanotranduction Pathways in the Regulation of Mitochondrial Homeostasis in Cardiomyocytes

(2021) Hongyu Liao et al.   Frontiers in Cell and Developmental Biology

Micro-electrode channel guide (µECG) technology: an online method for continuous electrical recording in a human beating heart-on-chip

(2021) Roberta Visone et al.   Biofabrication

Mechanical stimulation enhances development of scaffold‐free, 3D‐printed, engineered heart tissue grafts

(2021) Cecillia Lui et al.   Journal of Tissue Engineering and Regenerative Medicine

Mimicking cardiac tissue complexity through physical cues: A review on cardiac tissue engineering approaches

(2021) Troy Hendrickson et al.   Nanomedicine-Nanotechnology Biology and Medicine

Assessing the influence of perfusion on cardiac microtissue maturation: A heart‐on‐chip platform embedding peristaltic pump capabilities

(2021) Daniela Cruz‐Moreira et al.   BIOTECHNOLOGY AND BIOENGINEERING

Increased tissue stiffness triggers contractile dysfunction and telomere shortening in dystrophic cardiomyocytes

(2021) Alex C.Y. Chang et al.   Stem Cell Reports

Cardiomyocyte maturation: advances in knowledge and implications for regenerative medicine

(2020) Elaheh Karbassi et al.   Nature Reviews Cardiology

Human-iPSC-Derived Cardiac Stromal Cells Enhance Maturation in 3D Cardiac Microtissues and Reveal Non-cardiomyocyte Contributions to Heart Disease

(2020) Elisa Giacomelli et al.   Cell Stem Cell

Cardiomyocyte Maturation

(2020) Yuxuan Guo et al.   CIRCULATION RESEARCH

When Stiffness Matters: Mechanosensing in Heart Development and Disease

(2020) Roberto Gaetani et al.   Frontiers in Cell and Developmental Biology

BEaTS-α an open access 3D printed device for in vitro electromechanical stimulation of human induced pluripotent stem cells

(2020) David Cortes et al.   Scientific Reports

Bioreactor Platform for Biomimetic Culture and in situ Monitoring of the Mechanical Response of in vitro Engineered Models of Cardiac Tissue

(2020) Diana Massai et al.   Frontiers in Bioengineering and Biotechnology

A Miniaturized EHT Platform for Accurate Measurements of Tissue Contractile Properties

(2020) Milica Dostanic et al.   JOURNAL OF MICROELECTROMECHANICAL SYSTEMS

A microdevice platform for characterizing the effect of mechanical strain magnitudes on the maturation of iPSC-Cardiomyocytes

(2020) Wenkun Dou et al.   BIOSENSORS & BIOELECTRONICS

Cardiac Fibrotic Remodeling on a Chip with Dynamic Mechanical Stimulation

(2019) Ming Kong et al.   Advanced Healthcare Materials

Substrate Stiffness, Cell Anisotropy, and Cell–Cell Contact Contribute to Enhanced Structural and Calcium Handling Properties of Human Embryonic Stem Cell-Derived Cardiomyocytes

(2019) Marita L. Rodriguez et al.   ACS Biomaterials-Science & Engineering

High-speed mechano-active multielectrode array for investigating rapid stretch effects on cardiac tissue

(2019) Matthias Imboden et al.   Nature Communications

Pneumatic unidirectional cell stretching device for mechanobiological studies of cardiomyocytes

(2019) Joose Kreutzer et al.   Biomechanics and Modeling in Mechanobiology

Simultaneous measurement of excitation-contraction coupling parameters identifies mechanisms underlying contractile responses of hiPSC-derived cardiomyocytes

(2019) Berend J. van Meer et al.   Nature Communications

Cardiac Tissue Chips (CTCs) for Modeling Cardiovascular Disease

(2019) Aaron J. Rogers et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

A three-dimensional in vitro dynamic micro-tissue model of cardiac scar formation

(2018) Paola Occhetta et al.   Integrative Biology

Advanced maturation of human cardiac tissue grown from pluripotent stem cells

(2018) Kacey Ronaldson-Bouchard et al.   NATURE

A microfluidic platform for the high-throughput study of pathological cardiac hypertrophy

(2017) Hesam Parsa et al.   LAB ON A CHIP

Cardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues

(2017) Ilya Y. Shadrin et al.   Nature Communications

Heart-on-a-Chip: An Investigation of the Influence of Static and Perfusion Conditions on Cardiac (H9C2) Cell Proliferation, Morphology, and Alignment

(2017) Anna Kobuszewska et al.   SLAS Technology

Electrical and mechanical stimulation of cardiac cells and tissue constructs

(2016) Whitney L. Stoppel et al.   ADVANCED DRUG DELIVERY REVIEWS

Mechanical stimulation in the engineering of heart muscle

(2016) Norman Yu Liaw et al.   ADVANCED DRUG DELIVERY REVIEWS

Mechanical Stress Conditioning and Electrical Stimulation Promote Contractility and Force Maturation of Induced Pluripotent Stem Cell-Derived Human Cardiac TissueClinical Perspective

(2016) Jia-Ling Ruan et al.   CIRCULATION

Inherited heart disease - what can we expect from the second decade of human iPS cell research?

(2016) Milena Bellin et al.   FEBS LETTERS

Beating heart on a chip: a novel microfluidic platform to generate functional 3D cardiac microtissues

(2016) Anna Marsano et al.   LAB ON A CHIP

Instrumented cardiac microphysiological devices via multimaterial three-dimensional printing

(2016) Johan U. Lind et al.   NATURE MATERIALS

Human Engineered Cardiac Tissues Created Using Induced Pluripotent Stem Cells Reveal Functional Characteristics of BRAF-Mediated Hypertrophic Cardiomyopathy

(2016) Timothy J. Cashman et al.   PLoS One

On-chip assessment of human primary cardiac fibroblasts proliferative responses to uniaxial cyclic mechanical strain

(2015) Giovanni Stefano Ugolini et al.   BIOTECHNOLOGY AND BIOENGINEERING

Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy

(2015) J. T. Hinson et al.   SCIENCE

Mechanical Stress Promotes Maturation of Human Myocardium From Pluripotent Stem Cell-Derived Progenitors

(2015) Jia-Ling Ruan et al.   STEM CELLS

The effect of cyclic stretch on maturation and 3D tissue formation of human embryonic stem cell-derived cardiomyocytes

(2014) Anton Mihic et al.   BIOMATERIALS

Pneumatic cell stretching system for cardiac differentiation and culture

(2013) Joose Kreutzer et al.   MEDICAL ENGINEERING & PHYSICS

Recapitulating maladaptive, multiscale remodeling of failing myocardium on a chip

(2013) M. L. McCain et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increased afterload induces pathological cardiac hypertrophy: a new in vitro model

(2012) Marc N. Hirt et al.   BASIC RESEARCH IN CARDIOLOGY

Effects of mechanical stimulation induced by compression and medium perfusion on cardiac tissue engineering

(2012) Michal Shachar et al.   BIOTECHNOLOGY PROGRESS

Growth of Engineered Human Myocardium With Mechanical Loading and Vascular Coculture

(2011) Nathaniel L. Tulloch et al.   CIRCULATION RESEARCH

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

A Novel Miniaturized Multimodal Bioreactor for Continuous In Situ Assessment of Bioartificial Cardiac Tissue During Stimulation and Maturation

(2010) George Kensah et al.   TISSUE ENGINEERING PART C-METHODS

Substrate Stiffness Affects the Functional Maturation of Neonatal Rat Ventricular Myocytes

(2008) Jeffrey G. Jacot et al.   BIOPHYSICAL JOURNAL