Keratins: Biomarkers and modulators of apoptotic and necrotic cell death in the liver

Prevalence of genetic variants of keratins 8 and 18 in patients with drug-induced liver injury

(2015) Valentyn Usachov et al.   BMC Medicine

Keratins in health and disease

(2015) Diana M Toivola et al.   CURRENT OPINION IN CELL BIOLOGY

The impact of phlebotomy in nonalcoholic fatty liver disease: A prospective, randomized, controlled trial

(2015) Leon A. Adams et al.   HEPATOLOGY

Nonalcoholic Fatty Liver Disease

(2015) Mary E. Rinella   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Noninvasive Evaluation of Nonalcoholic Fatty Liver Disease

(2015) Laurent Castera   SEMINARS IN LIVER DISEASE

Large oncosomes contain distinct protein cargo and represent a separate functional class of tumor-derived extracellular vesicles

(2015) Valentina R. Minciacchi et al.   Oncotarget

Relationship Between Changes in Serum Levels of Keratin 18 and Changes in Liver Histology in Children and Adults With Nonalcoholic Fatty Liver Disease

(2014) Raj Vuppalanchi et al.   Clinical Gastroenterology and Hepatology

Cell Death and Cell Death Responses in Liver Disease: Mechanisms and Clinical Relevance

(2014) Tom Luedde et al.   GASTROENTEROLOGY

Mutation of caspase-digestion sites in keratin 18 interferes with filament reorganization, and predisposes to hepatocyte necrosis and loss of membrane integrity

(2014) S. V. W. Weerasinghe et al.   JOURNAL OF CELL SCIENCE

Biomarkers of liver cell death

(2014) Akiko Eguchi et al.   JOURNAL OF HEPATOLOGY

Post-translational modifications of intermediate filament proteins: mechanisms and functions

(2014) Natasha T. Snider et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Character and Temporal Evolution of Apoptosis in Acetaminophen-Induced Acute Liver Failure*

(2013) Lucia A. Possamai et al.   CRITICAL CARE MEDICINE

Keratin 19: a key role player in the invasion of human hepatocellular carcinomas

(2013) Olivier Govaere et al.   GUT

Caspase-cleaved fragments of cytokeratin-18 as a marker of inflammatory activity in chronic hepatitis B virus infection

(2013) Chang Bum Bae et al.   JOURNAL OF CLINICAL VIROLOGY

Limited value of plasma cytokeratin-18 as a biomarker for NASH and fibrosis in patients with non-alcoholic fatty liver disease

(2013) Kenneth Cusi et al.   JOURNAL OF HEPATOLOGY

Serum cytochrome c and m30-neoepitope of cytokeratin-18 in chronic hepatitis C

(2013) Anna Parfieniuk-Kowerda et al.   LIVER INTERNATIONAL

Assessment of non-alcoholic fatty liver disease using serum total cell death and apoptosis markers

(2012) J. Shen et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Plasma biomarkers of lower gastrointestinal and liver acute GVHD

(2012) A. C. Harris et al.   BLOOD

Phase 2 trial of linifanib (ABT-869) in patients with unresectable or metastatic hepatocellular carcinoma

(2012) Han Chong Toh et al.   CANCER

Keratins

(2012) Pavel Strnad et al.   CURRENT OPINION IN GASTROENTEROLOGY

Development of an Accurate Index for Predicting Outcomes of Patients With Acute Liver Failure

(2012) Anna Rutherford et al.   GASTROENTEROLOGY

Liver progenitor cell markers correlate with liver damage and predict short-term mortality in patients with alcoholic hepatitis

(2012) Pau Sancho-Bru et al.   HEPATOLOGY

Non-invasive diagnosis of non-alcoholic steatohepatitis by combined serum biomarkers

(2012) Jiayun Shen et al.   JOURNAL OF HEPATOLOGY

Molecular forms of HMGB1 and keratin-18 as mechanistic biomarkers for mode of cell death and prognosis during clinical acetaminophen hepatotoxicity

(2012) Daniel J. Antoine et al.   JOURNAL OF HEPATOLOGY

The nuclear lamins: flexibility in function

(2012) Brian Burke et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanisms of Cell Death in Acute Liver Failure

(2012) Heike Bantel et al.   Frontiers in Physiology

Prospective biopsy-controlled evaluation of cell death biomarkers for prediction of liver fibrosis and nonalcoholic steatohepatitis

(2011) Diana Joka et al.   HEPATOLOGY

Nucleos(t)ide analogue treatment reduces apoptotic activity in patients with chronic hepatitis B

(2011) Harald Farnik et al.   JOURNAL OF CLINICAL VIROLOGY

Circulating apoptotic and necrotic cell death markers in patients with acute liver injury

(2011) Darren G. N. Craig et al.   LIVER INTERNATIONAL

A new composite model including metabolic syndrome, alanine aminotransferase and cytokeratin-18 for the diagnosis of non-alcoholic steatohepatitis in morbidly obese patients

(2010) R. Anty et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Keratin Variants Predispose to Acute Liver Failure and Adverse Outcome: Race and Ethnic Associations

(2010) Pavel Strnad et al.   GASTROENTEROLOGY

Disease progression of non-alcoholic fatty liver disease: a prospective study with paired liver biopsies at 3 years

(2010) V. W.-S. Wong et al.   GUT

Acute liver failure is associated with elevated liver stiffness and hepatic stellate cell activation

(2010) Alexander Dechêne et al.   HEPATOLOGY

Cytokeratin 18-based modification of the MELD score improves prediction of spontaneous survival after acute liver injury

(2010) Lars P. Bechmann et al.   JOURNAL OF HEPATOLOGY

An apoptosis panel for nonalcoholic steatohepatitis diagnosis

(2010) Tarek I. Abu-Rajab Tamimi et al.   JOURNAL OF HEPATOLOGY

Cell Death and Fibrogenesis

(2010) Wajahat Mehal et al.   SEMINARS IN LIVER DISEASE

Keratin variants are overrepresented in primary biliary cirrhosis and associate with disease severity

(2009) Bihui Zhong et al.   HEPATOLOGY

Keratins modulate the shape and function of hepatocyte mitochondria: a mechanism for protection from apoptosis

(2009) G.-Z. Tao et al.   JOURNAL OF CELL SCIENCE

“IF-pathies”: a broad spectrum of intermediate filament–associated diseases

(2009) M. Bishr Omary   JOURNAL OF CLINICAL INVESTIGATION

Toward unraveling the complexity of simple epithelial keratins in human disease

(2009) M. Bishr Omary et al.   JOURNAL OF CLINICAL INVESTIGATION

Quantitation of tissue polypeptide antigen (TPA) in hepatic and systemic circulation in patients with chronic liver diseases

(2009) Claudio Puoti et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Cytokeratin 18 Fragment Levels as a Noninvasive Biomarker for Nonalcoholic Steatohepatitis in Bariatric Surgery Patients

(2008) Dima L. Diab et al.   Clinical Gastroenterology and Hepatology

Risk of severe liver disease in nonalcoholic fatty liver disease with normal aminotransferase levels: A role for insulin resistance and diabetes

(2008) Anna Ludovica Fracanzani et al.   HEPATOLOGY

Caspase activation is associated with spontaneous recovery from acute liver failure

(2008) Xandra Volkmann et al.   HEPATOLOGY

Monitoring of epithelial cell caspase activation via detection of durable keratin fragment formation

(2008) G-Z Tao et al.   JOURNAL OF PATHOLOGY

A Novel Diagnostic Biomarker Panel for Obesity-related Nonalcoholic Steatohepatitis (NASH)

(2008) Zobair M. Younossi et al.   OBESITY SURGERY

Cytokeratin fragments in the serum: Their utility for the management of oral cancer

(2008) Sharada S. Sawant et al.   ORAL ONCOLOGY

The Human Intermediate Filament Database: comprehensive information on a gene family involved in many human diseases

(2007) Ildiko Szeverenyi et al.   HUMAN MUTATION

Apoptosis: controlled demolition at the cellular level

(2007) Rebecca C. Taylor et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY