Nicotinamide adenine dinucleotide biosynthesis promotes liver regeneration

Liver-specific loss of Perilipin 2 alleviates diet-induced hepatic steatosis, inflammation, and fibrosis

(2016) Charles P. Najt et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Perilipin2 plays a positive role in adipocytes during lipolysis by escaping proteasomal degradation

(2016) Yu Takahashi et al.   Scientific Reports

SIRT1-Mediated eNAMPT Secretion from Adipose Tissue Regulates Hypothalamic NAD+ and Function in Mice

(2015) Myeong Jin Yoon et al.   Cell Metabolism

Akt-mediated foxo1 inhibition is required for liver regeneration

(2015) Montse Pauta et al.   HEPATOLOGY

Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice

(2015) Karim Gariani et al.   HEPATOLOGY

Degradation of lipid droplet-associated proteins by chaperone-mediated autophagy facilitates lipolysis

(2015) Susmita Kaushik et al.   NATURE CELL BIOLOGY

Hepato-protective effect of resveratrol against acetaminophen-induced liver injury is associated with inhibition of CYP-mediated bioactivation and regulation of SIRT1–p53 signaling pathways

(2015) Ying Wang et al.   TOXICOLOGY LETTERS

Increasing NAD Synthesis in Muscle via Nicotinamide Phosphoribosyltransferase Is Not Sufficient to Promote Oxidative Metabolism

(2014) David W. Frederick et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nicotinamide Phosphoribosyltransferase Promotes Epithelial-to-Mesenchymal Transition as a Soluble Factor Independent of Its Enzymatic Activity

(2014) Debora Soncini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nicotinamide Phosphoribosyl Transferase/Pre-B Cell Colony-Enhancing Factor/Visfatin Is Required for Lymphocyte Development and Cellular Resistance to Genotoxic Stress

(2014) A. Rongvaux et al.   JOURNAL OF IMMUNOLOGY

Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity

(2014) Daniel Kraus et al.   NATURE

Addendum: A reproducible and well-tolerated method for 2/3 partial hepatectomy in mice

(2014) Claudia Mitchell et al.   Nature Protocols

Perilipins 2 and 3 lack a carboxy-terminal domain present in perilipin 1 involved in sequestering ABHD5 and suppressing basal lipolysis

(2014) S. Patel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SIRT1 controls liver regeneration by regulating bile acid metabolism through farnesoid X receptor and mammalian target of rapamycin signaling

(2013) Juan L. García-Rodríguez et al.   HEPATOLOGY

Perilipin-2-null mice are protected against diet-induced obesity, adipose inflammation, and fatty liver disease

(2013) James L. McManaman et al.   JOURNAL OF LIPID RESEARCH

Visfatin/NAMPT: A Multifaceted Molecule with Diverse Roles in Physiology and Pathophysiology

(2012) Tuva B. Dahl et al.   Annual Review of Nutrition

The NAD+ Precursor Nicotinamide Riboside Enhances Oxidative Metabolism and Protects against High-Fat Diet-Induced Obesity

(2012) Carles Cantó et al.   Cell Metabolism

Hepatocyte-specific deletion of farnesoid X receptor delays but does not inhibit liver regeneration after partial hepatectomy in mice

(2012) Prachi Borude et al.   HEPATOLOGY

Protective effects of nicotinamide against acetaminophen-induced acute liver injury

(2012) Youdan Shi et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Effects of perilipin 2 antisense oligonucleotide treatment on hepatic lipid metabolism and gene expression

(2012) Yumi Imai et al.   PHYSIOLOGICAL GENOMICS

The reduction of SIRT1 in livers of old mice leads to impaired body homeostasis and to inhibition of liver proliferation

(2011) Jingling Jin et al.   HEPATOLOGY

Hepatic FoxOs Regulate Lipid Metabolism via Modulation of Expression of the Nicotinamide Phosphoribosyltransferase Gene

(2011) Rongya Tao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nicotinamide phosphoribosyltransferase (NAMPT/PBEF/visfatin) is constitutively released from human hepatocytes

(2009) A. Garten et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hepatocyte-Specific Deletion of SIRT1 Alters Fatty Acid Metabolism and Results in Hepatic Steatosis and Inflammation

(2009) Aparna Purushotham et al.   Cell Metabolism

Therapeutic potential of SIRT1 and NAMPT-mediated NAD biosynthesis in type 2 diabetes

(2009) Shin-ichiro Imai   Frontiers in Bioscience-Landmark

Adenine nucleotide changes in the remnant liver: An early signal for regeneration after partial hepatectomy

(2008) Sara Crumm et al.   HEPATOLOGY

A reproducible and well-tolerated method for 2/3 partial hepatectomy in mice

(2008) Claudia Mitchell et al.   Nature Protocols

Nampt: linking NAD biology, metabolism and cancer

(2008) Antje Garten et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM