Liver-specific loss of Perilipin 2 alleviates diet-induced hepatic steatosis, inflammation, and fibrosis

Histidine-rich glycoprotein promotes macrophage activation and inflammation in chronic liver disease

(2016) Matthias Bartneck et al.   HEPATOLOGY

PLIN2 inhibits insulin-induced glucose uptake in myoblasts through the activation of the NLRP3 inflammasome

(2015) KYUNG-AH CHO et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

S-Adenosylmethionine increases circulating very-low density lipoprotein clearance in non-alcoholic fatty liver disease

(2015) Maite Martínez-Uña et al.   JOURNAL OF HEPATOLOGY

Degradation of lipid droplet-associated proteins by chaperone-mediated autophagy facilitates lipolysis

(2015) Susmita Kaushik et al.   NATURE CELL BIOLOGY

Impact of dietary fat on the development of non-alcoholic fatty liver disease in Ldlr−/− mice

(2015) Donald B. Jump et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

ER stress induces NLRP3 inflammasome activation and hepatocyte death

(2015) C Lebeaupin et al.   Cell Death & Disease

Structural and Functional Assessment of Perilipin 2 Lipid Binding Domain(s)

(2014) Charles P. Najt et al.   BIOCHEMISTRY

Biogenesis of the multifunctional lipid droplet: Lipids, proteins, and sites

(2014) Albert Pol et al.   JOURNAL OF CELL BIOLOGY

Unraveling the complexity of lipid body organelles in human eosinophils

(2014) Rossana C. N. Melo et al.   JOURNAL OF LEUKOCYTE BIOLOGY

A monophasic extraction strategy for the simultaneous lipidome analysis of polar and nonpolar retina lipids

(2014) Todd A. Lydic et al.   JOURNAL OF LIPID RESEARCH

Absence of Perilipin 2 Prevents Hepatic Steatosis, Glucose Intolerance and Ceramide Accumulation in Alcohol-Fed Mice

(2014) Rotonya M. Carr et al.   PLoS One

Mutations disrupting the Kennedy phosphatidylcholine pathway in humans with congenital lipodystrophy and fatty liver disease

(2014) F. Payne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Excess S-adenosylmethionine reroutes phosphatidylethanolamine towards phosphatidylcholine and triglyceride synthesis

(2013) Maite Martínez-Uña et al.   HEPATOLOGY

Perilipin-2-null mice are protected against diet-induced obesity, adipose inflammation, and fatty liver disease

(2013) James L. McManaman et al.   JOURNAL OF LIPID RESEARCH

Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis

(2013) Quentin M. Anstee et al.   Nature Reviews Gastroenterology & Hepatology

Direct interaction of Plin2 with lipids on the surface of lipid droplets: a live cell FRET analysis

(2012) Avery L. McIntosh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Comprehensive Lipidome Profiling of Isogenic Primary and Metastatic Colon Adenocarcinoma Cell Lines

(2012) Cassie J. Fhaner et al.   ANALYTICAL CHEMISTRY

PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress

(2012) T Verfaillie et al.   CELL DEATH AND DIFFERENTIATION

Effects of perilipin 2 antisense oligonucleotide treatment on hepatic lipid metabolism and gene expression

(2012) Yumi Imai et al.   PHYSIOLOGICAL GENOMICS

Phosphatidylcholine Synthesis for Lipid Droplet Expansion Is Mediated by Localized Activation of CTP:Phosphocholine Cytidylyltransferase

(2011) Natalie Krahmer et al.   Cell Metabolism

Sequential Synthesis and Methylation of Phosphatidylethanolamine Promote Lipid Droplet Biosynthesis and Stability in Tissue Culture andin Vivo

(2011) Gerd Hörl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of lipid droplets in metabolic disease in rodents and humans

(2011) Andrew S. Greenberg et al.   JOURNAL OF CLINICAL INVESTIGATION

Reversible Ponceau staining as a loading control alternative to actin in Western blots

(2010) Isabel Romero-Calvo et al.   ANALYTICAL BIOCHEMISTRY

Mitochondria and Redox Signaling in Steatohepatitis

(2010) E. Matthew Morris et al.   ANTIOXIDANTS & REDOX SIGNALING

Absence of adipose differentiation related protein upregulates hepatic VLDL secretion, relieves hepatosteatosis, and improves whole body insulin resistance in leptin-deficient mice

(2010) Benny Hung-Junn Chang et al.   JOURNAL OF LIPID RESEARCH

Dysfunctional very-low-density lipoprotein synthesis and release is a key factor in nonalcoholic steatohepatitis pathogenesis

(2009) Koji Fujita et al.   HEPATOLOGY

15(S)-Lipoxygenase-1 associates with neutral lipid droplets in macrophage foam cells: evidence of lipid droplet metabolism

(2009) Ginny L. Weibel et al.   JOURNAL OF LIPID RESEARCH

Overexpression of sterol carrier protein-2 differentially alters hepatic cholesterol accumulation in cholesterol-fed mice

(2009) Barbara P. Atshaves et al.   JOURNAL OF LIPID RESEARCH

High Dietary Fat Exacerbates Weight Gain and Obesity in Female Liver Fatty Acid Binding Protein Gene-Ablated Mice

(2009) Barbara P. Atshaves et al.   LIPIDS

Adipophilin affects the expression of TNF-α, MCP-1, and IL-6 in THP-1 macrophages

(2009) F. L. Chen et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Inhibition of ADRP prevents diet-induced insulin resistance

(2008) Gladys M. Varela et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Lipid Bodies Are Reservoirs of Cyclooxygenase-2 and Sites of Prostaglandin-E2 Synthesis in Colon Cancer Cells

(2008) M. T. Accioly et al.   CANCER RESEARCH

Deficiency of Adipose Differentiation-Related Protein Impairs Foam Cell Formation and Protects Against Atherosclerosis

(2008) Antoni Paul et al.   CIRCULATION RESEARCH

Consequences of Lipid Droplet Coat Protein Downregulation in Liver Cells: Abnormal Lipid Droplet Metabolism and Induction of Insulin Resistance

(2008) M. Bell et al.   DIABETES

Molecular Mechanisms and Therapeutic Targets in Steatosis and Steatohepatitis

(2008) N. Anderson et al.   PHARMACOLOGICAL REVIEWS