Blood transcriptional biomarkers of acute viral infection for detection of pre-symptomatic SARS-CoV-2 infection: a nested, case-control diagnostic accuracy study

Translation of a Host Blood RNA Signature Distinguishing Bacterial From Viral Infection Into a Platform Suitable for Development as a Point-of-Care Test

(2021) Ivana Pennisi et al.   JAMA Pediatrics

Discordant neutralizing antibody and T cell responses in asymptomatic and mild SARS-CoV-2 infection

(2021) Catherine J. Reynolds et al.   Science Immunology

Concise whole blood transcriptional signatures for incipient tuberculosis: a systematic review and patient-level pooled meta-analysis

(2020) Rishi K Gupta et al.   Lancet Respiratory Medicine

Type I Interferon in Children with Viral or Bacterial Infections

(2020) Sophie Trouillet-Assant et al.   CLINICAL CHEMISTRY

COVID-19: PCR screening of asymptomatic health-care workers at London hospital

(2020) Thomas A Treibel et al.   LANCET

Challenges in Laboratory Diagnosis of the Novel Coronavirus SARS-CoV-2

(2020) Nadin Younes et al.   Viruses-Basel

Blood transcriptional biomarkers for active pulmonary tuberculosis in a high-burden setting: a prospective, observational, diagnostic accuracy study

(2020) Carolin T Turner et al.   Lancet Respiratory Medicine

Blood transcriptomic discrimination of bacterial and viral infections in the emergency department: a multi-cohort observational validation study

(2020) Dayle Sampson et al.   BMC Medicine

A blood-based host gene expression assay for early detection of respiratory viral infection: an index-cluster prospective cohort study

(2020) Micah T McClain et al.   LANCET INFECTIOUS DISEASES

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

(2020) Qian Zhang et al.   SCIENCE

Autoantibodies against type I IFNs in patients with life-threatening COVID-19

(2020) Paul Bastard et al.   SCIENCE

Infectivity of asymptomatic versus symptomatic COVID-19

(2020) Andrew A Sayampanathan et al.   LANCET

Genetic mechanisms of critical illness in Covid-19

(2020) Erola Pairo-Castineira et al.   NATURE

An Outbreak of Covid-19 on an Aircraft Carrier

(2020) Matthew R. Kasper et al.   NEW ENGLAND JOURNAL OF MEDICINE

Nucleic acid amplification tests on respiratory samples for the diagnosis of coronavirus infections: a systematic review and meta-analysis

(2020) Mona Mustafa Hellou et al.   CLINICAL MICROBIOLOGY AND INFECTION

A qPCR expression assay of IFI44L gene differentiates viral from bacterial infections in febrile children

(2019) Alberto Gómez-Carballa et al.   Scientific Reports

Validation of a host response test to distinguish bacterial and viral respiratory infection

(2019) Emily C. Lydon et al.   EBioMedicine

Validation of a Host Response Assay, Septicyte™ LAB, for Discriminating Sepsis from SIRS in the ICU

(2018) Russell R Miller III et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Consolidated principles for screening based on a systematic review and consensus process

(2018) Mark J. Dobrow et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

A molecular multi-gene classifier for disease diagnostics

(2018) Randolph Lopez et al.   Nature Chemistry

Genomic Circuitry Underlying Immunological Response to Pediatric Acute Respiratory Infection

(2018) Sarah E. Henrickson et al.   Cell Reports

Comparison of RT-qPCR and Nanostring in the measurement of blood interferon response for the diagnosis of type I interferonopathies

(2018) Rémi Pescarmona et al.   CYTOKINE

Host Gene Expression in Nose and Blood for the Diagnosis of Viral Respiratory Infection

(2018) Jinsheng Yu et al.   JOURNAL OF INFECTIOUS DISEASES

2012. FilmArray® Measurement of Host Response Signatures RapidLy Discriminates Viral, Bacterial, and Non-infectious Etiologies of Illness

(2018) Ephraim L Tsalik et al.   Open Forum Infectious Diseases

A novel immune biomarkerIFI27discriminates between influenza and bacteria in patients with suspected respiratory infection

(2017) Benjamin M. Tang et al.   EUROPEAN RESPIRATORY JOURNAL

A Four-Biomarker Blood Signature Discriminates Systemic Inflammation Due to Viral Infection Versus Other Etiologies

(2017) D. L. Sampson et al.   Scientific Reports

Diagnostic Test Accuracy of a 2-Transcript Host RNA Signature for Discriminating Bacterial vs Viral Infection in Febrile Children

(2016) Jethro A. Herberg et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Near-optimal probabilistic RNA-seq quantification

(2016) Nicolas L Bray et al.   NATURE BIOTECHNOLOGY

Robust classification of bacterial and viral infections via integrated host gene expression diagnostics

(2016) Timothy E. Sweeney et al.   Science Translational Medicine

Host gene expression classifiers diagnose acute respiratory illness etiology

(2016) Ephraim L. Tsalik et al.   Science Translational Medicine

Integrated, Multi-cohort Analysis Identifies Conserved Transcriptional Signatures across Multiple Respiratory Viruses

(2015) Marta Andres-Terre et al.   IMMUNITY

Olfactomedin 4 Serves as a Marker for Disease Severity in Pediatric Respiratory Syncytial Virus (RSV) Infection

(2015) H. K. Brand et al.   PLoS One

A comprehensive time-course–based multicohort analysis of sepsis and sterile inflammation reveals a robust diagnostic gene set

(2015) Timothy E. Sweeney et al.   Science Translational Medicine

A Host-Based RT-PCR Gene Expression Signature to Identify Acute Respiratory Viral Infection

(2013) A. K. Zaas et al.   Science Translational Medicine

Temporal Dynamics of Host Molecular Responses Differentiate Symptomatic and Asymptomatic Influenza A Infection

(2011) Yongsheng Huang et al.   PLoS Genetics

Gene Expression Signatures Diagnose Influenza and Other Symptomatic Respiratory Viral Infections in Humans

(2009) Aimee K. Zaas et al.   Cell Host & Microbe

Mitochondrial localization and pro-apoptotic effects of the interferon-inducible protein ISG12a

(2008) Shaun Rosebeck et al.   APOPTOSIS