Article
Biochemistry & Molecular Biology
Chan Jung Liu, Yau Sheng Tsai, Ho Shiang Huang
Summary: This study demonstrates that statins can suppress hyperlipidemia-induced CaOx nephrolithiasis by restoring the expression of anti-lithic protein, leading to a decrease in renal CaOx stone deposits and a change in the dominant calcium crystal composition.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Multidisciplinary Sciences
Seow Huey Choy, Selina Ann Nyanatay, Selvalingam Sothilingam, Rohan Malek, J. R. Sathiyananthan, Charng Chee Toh, Murali Sundram, Noor Ashani Md Yusoff, Poongkodi Nagappan, Shakirin Kamaruzaman, Wei Sien Yeoh, Teng Aik Ong, Jasmine Lim
Summary: This study aimed to investigate the renal function profile and associated factors in Asian renal stone formers. The results showed that reduced renal function varies between ethnicities and all age groups of patients, and is associated with factors such as age, ethnicity, diabetes, and hypertension.
Article
Microbiology
Sen-Yuan Hong, Lin-Tao Miao, Jia-Qiao Zhang, Shao-Gang Wang
Summary: This study reveals the close relationship between urolithiasis and the urinary microbiome, and provides detailed analysis of the urobiome on different sides using sequencing techniques. The results show significant differences in the urobiome between different sides, suggesting different roles in stone formation. The findings have important implications for guiding the selection of appropriate medical treatments.
Article
Radiology, Nuclear Medicine & Medical Imaging
Bo Mussmann, Maryann Hardy, Helene Jung, Ming Ding, Palle J. Osther, Ole Graumann
Summary: The study found that dual energy computed tomography can accurately identify and classify renal stones, providing support for clinical decision-making. The results suggest that CT systems using fast kV switching have the potential to be a low-dose diagnostic tool for precise localization and classification of renal stones in vivo.
ACADEMIC RADIOLOGY
(2021)
Article
Medicine, General & Internal
Nasser A. Dhayat, Olivier Bonny, Beat Roth, Andreas Christe, Alexander Ritter, Nilufar Mohebbi, Nicolas Faller, Lisa Pellegrini, Giulia Bedino, Reto M. Venzin, Philipp Grosse, Carina Husler, Irene Koneth, Christian Bucher, Rosaria Del Giorno, Luca Gabutti, Michael Mayr, Urs Odermatt, Florian Buchkremer, Thomas Ernandez, Catherine Stoermann-Chopard, Daniel Teta, Bruno Vogt, Marie Roumet, Luca Tamo, Grazia M. Cereghetti, Sven Trelle, Daniel G. Fuster
Summary: This study aimed to investigate the dose-response effect of hydrochlorothiazide agents for preventing the recurrence of kidney stones. The results showed that there was no significant difference in the incidence of recurrent stones among patients receiving hydrochlorothiazide at doses of 12.5 mg, 25 mg, or 50 mg compared to placebo. However, the use of hydrochlorothiazide was associated with a higher risk of adverse reactions.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Article
Biochemistry & Molecular Biology
Jae Yong Jeong, Kyung Jin Oh, Jun Seok Sohn, Dae Young Jun, Jae Il Shin, Keum Hwa Lee, Joo Yong Lee
Summary: This study investigated the phenotypes, clinical courses, and genetic analyses of 10 Korean patients with cystinuria. The study identified six new mutations and found that compound heterozygous type A was the most common genotype among the patients.
Article
Urology & Nephrology
Fidelis Uwumiro, Victory Okpujie, Festa Madu, Olawale Abesin, Naomi Chigbu, Cynthia Isuekebhor, Loveth Ezennaya, Oluwatobi Olaomi, Michael Bojerenu, Bolanle Aderehinwo
Summary: Frailty is associated with lower chances of early surgical intervention, higher hospital costs, and increased likelihood of non-home discharges and peri-operative complications for urolithiasis hospitalizations.
WORLD JOURNAL OF UROLOGY
(2023)
Article
Medicine, General & Internal
Yucheng Ma, Zhongyu Jian, Liyuan Xiang, Liang Zhou, Xi Jin, Deyi Luo, Hong Li, Kun-Jie Wang
Summary: Preoperative ipsilateral renal function may affect the success of kidney stone removal with flexible ureteroscopic lithotripsy. A predictive model based on stone volume, lower calyx stones, age, body mass index and estimated glomerular filtration rate was developed and verified with a mean area under the curve of 0.715.
Article
Medicine, General & Internal
Zhu Wei Lim, I-Duo Wang, Feng-Cheng Liu, Chi-Hsiang Chung, Je-Ming Hu, Pei-Yi Tsai, Wu-Chien Chien
Summary: The study revealed that patients with NASD are at higher risk for all causes of injuries, particularly among the elderly. Falls are the most prevalent cause of injury.
Article
Urology & Nephrology
Walter Ludwig Strohmaier, Judit Bonkovic-Oszi
Summary: Seasonal variation is observed in renal colic among uric acid stone formers in Germany, but not in metabolic parameters. The reasons for this variation are unclear and further studies are needed to better understand these findings.
WORLD JOURNAL OF UROLOGY
(2022)
Review
Nutrition & Dietetics
Paleerath Peerapen, Visith Thongboonkerd
Summary: Kidney stone disease is a global health problem with increasing prevalence and high recurrence rate. Effective preventive strategies, including nutrition-based approaches, are crucial to reduce the burden of this disease. This article provides up-to-date knowledge and summarizes various preventive measures, including fluid intake, lifestyle modifications, dietary management, and the use of natural bioactive products and medications.
ADVANCES IN NUTRITION
(2023)
Article
Urology & Nephrology
Katsuhiro Ito, Toshifumi Takahashi, Shinya Somiya, Toru Kanno, Yoshihito Higashi, Hitoshi Yamada
Summary: This single-center retrospective cohort study evaluated the risk of repeat surgery and stone-related events after flexible ureteroscopy for renal stones. Factors such as younger age, history of stone surgery, larger preoperative stone burden, and larger residual fragment were associated with future intervention. The study proposed a simple predictive tool based on these risk factors to stratify patients and guide treatment decisions.
Article
Biology
Yueh-Er Chiou, Chi-Hsiang Chung, Wu-Chien Chien, Pei-Kwei Tsay, Hung-Cheng Kan, Wen-Hui Weng
Summary: This study investigated the effectiveness of different interventions for urolithiasis and analyzed the association with various risk factors. The results showed that patients who received lithotripsy had a higher risk of repeat treatment, especially those who underwent extracorporeal shock wave lithotripsy and percutaneous nephrolithotomy. Age, season, level of care, and comorbidities were also found to be closely related to repeat treatment rates.
Article
Urology & Nephrology
Roswitha Siener, Helena Herwig, Jakob Ruedy, Reinhold M. Schaefer, Philipp Lossin, Albrecht Hesse
Summary: The composition of urinary stones is closely related to gender and age. Calcium oxalate and uric acid stones are more common in men. The proportions of different crystal forms provide clues to the formation of stones. The peak incidence of urinary stones occurs during the most active phase of working life.
WORLD JOURNAL OF UROLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Soyeoun Kim, Thi Xuan Mai Tran, Huiyeon Song, Seungho Ryu, Yoosoo Chang, Boyoung Park
Summary: This study investigated the risk of breast cancer associated with the combination of mammographic density and benign breast disease in Korean women. The results showed that women with both high breast density and benign breast disease had an elevated risk of developing breast cancer.
Article
Urology & Nephrology
Hung-Chih Chen, Che-Yi Chou, Hsuan-Jen Lin, Chiu-Ching Huang, Chiz-Tzung Chang
Article
Urology & Nephrology
Hsuan-Jen Lin, Chung-Chih Lin, Hsuan Ming Lin, Hsuan-Ju Chen, Che-Chen Lin, Chiz-Tzung Chang, Che-Yi Chou, Chiu-Ching Huang
Article
Multidisciplinary Sciences
Jin-Hua Chen, Jia-Lian Yang, Che-Yi Chou, Jiun-Yi Wang, Chin-Chuan Hung
SCIENTIFIC REPORTS
(2018)
Article
Endocrinology & Metabolism
Yi-Hao Peng, Chien-Wen Huang, Che-Yi Chou, Hung-Jie Chiou, Hsuan-Ju Chen, Trong-Neng Wu, Wen-Chao Ho
Article
Hematology
Hung-Chih Chen, Hsuan-Jen Lin, Chiu-Ching Huang, Chiz-Tzung Chang, Che-Yi Chou
BLOOD PURIFICATION
(2019)
Review
Oncology
Hsuan-Jen Lin, Phillip C-Y Sheu, Jeffrey J. P. Tsai, Charles C. N. Wang, Che-Yi Chou
Article
Urology & Nephrology
Ai-Ling Shen, Hsiu-Li Lin, Hsiu-Chen Lin, Yuan-Fu Tseng, Chien-Yeh Hsu, Che-Yi Chou
Article
Oncology
Jia-Lian Yang, Charles C. N. Wang, Jia-Hua Cai, Che-Yi Chou, Yu-Chao Lin, Chin-Chuan Hung
Article
Respiratory System
Yi-Fen Lei, Hsiu-Chen Lin, Hsiu-Li Lin, Yow-Sheng Uang, Hui-Wen Cheng, Li-Hsuan Wang
INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
(2020)
Article
Biotechnology & Applied Microbiology
Che-Yi Chou, Chin-Chung Tseng, Jin-Bor Chen, Chin-Chuan Hung, Chiu-Ching Huang
Summary: Encapsulating peritoneal sclerosis (EPS) is a rare but serious complication of peritoneal dialysis (PD). Effluent MMP-2 levels were significantly higher in EPS patients compared to normal PD patients, and both MMP-2 levels and PD duration were independently associated with EPS risks. A nomogram based on effluent MMP-2 levels and PD duration may accurately predict EPS.
BIOMED RESEARCH INTERNATIONAL
(2021)
Article
Medicine, General & Internal
Hsiu-Chen Lin, Yuan-Fu Tseng, Ai-Ling Shen, Jane Chen-Jui Chao, Chien-Yeh Hsu, Hsiu-Li Lin
Summary: This study found that the use of ARBs reduced the risk of developing Parkinson's disease in newly diagnosed hypertensive patients, suggesting that it may be an effective neuroprotective strategy.
AMERICAN JOURNAL OF MEDICINE
(2022)
Review
Oncology
Hsuan-Jen Lin, Rouh-Mei Hu, Hung-Chih Chen, Chung-Chih Lin, Chi-Yu Lee, Che-Yi Chou
Summary: Urothelial carcinoma of the bladder (UCB) is a common genitourinary cancer. CA125, a well-known tumor marker for ovarian cancer, can be used as a diagnostic marker for advanced UCB. This meta-analysis reviewed published studies in English and Chinese and found that serum CA125 can help distinguish advanced UCB from non-advanced UCB patients.
Article
Urology & Nephrology
Jia-Wen Lai, Hsuan-Jen Lin, Che-Yi Chou
Summary: The ultrafiltration volume increased and fluid overload symptoms improved in PD patients after the use of SGLT-2 inhibitors.
Article
Peripheral Vascular Disease
Ya-Chi Cheng, Yi-Chun Kuo, Pei-Chi Chang, Ya-Ching Li, Wan-Ting Huang, Wei Chen, Che-Yi Chou
Summary: In community-dwelling elderly individuals, dyslipidemia is associated with geriatric functional impairment, while hypertension and diabetes are not. Lower renal function is linked to decreased mobility and nutrition in this population. Further research is needed to investigate whether treating dyslipidemia can reduce geriatric functional impairment.
VASCULAR HEALTH AND RISK MANAGEMENT
(2021)
Article
Multidisciplinary Sciences
Che-Yi Chou, Kuo-Hsiung Shu, Hung-Chun Chen, Ming-Chang Wang, Chia-Chu Chang, Bang-Gee Hsu, Tzen-Wen Chen, Chien-Lung Chen, Chiu-Ching Huang
SCIENTIFIC REPORTS
(2019)
