Optical Imaging of Beta-Amyloid Plaques in Alzheimer’s Disease

Coherent Anti-Stokes Raman Scattering Microscopy and Its Applications

(2021) Shaowei Li et al.   Frontiers in Physics

Dose–effect relationships for PBM in the treatment of Alzheimer’s disease

(2021) Renlong Zhang et al.   JOURNAL OF PHYSICS D-APPLIED PHYSICS

In vitro study of the mechanism of intraneuronal β-amyloid aggregation in Alzheimer’s disease

(2020) Shahad Alsunusi et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Post-mortem analyses of PiB and flutemetamol in diffuse and cored amyloid-β plaques in Alzheimer’s disease

(2020) Milos D. Ikonomovic et al.   ACTA NEUROPATHOLOGICA

Possible neuroprotective effects of rasagiline in Alzheimer’s disease: a SPECT study

(2020) In-Uk Song et al.   ACTA RADIOLOGICA

A multiscale study on photophysical properties of a novel fluorescent probe for imaging amyloid‐ β in Alzheimer's disease

(2020) Yujin Zhang et al.   INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY

Detection of cerebral tauopathy in P301L mice using high-resolution large-field multifocal illumination fluorescence microscopy

(2020) Ruiqing Ni et al.   Biomedical Optics Express

SPECT imaging of distribution and retention of a brain-penetrating bispecific amyloid-β antibody in a mouse model of Alzheimer’s disease

(2020) Tobias Gustavsson et al.   Translational Neurodegeneration

Identification of intraneuronal amyloid beta oligomers in locus coeruleus neurons of Alzheimer’s patients and their potential impact on inhibitory neurotransmitter receptors and neuronal excitability

(2020) Louise Kelly et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Label-free multiphoton imaging of β-amyloid plaques in Alzheimer’s disease mouse models

(2019) Shu Wang et al.   Neurophotonics

In vivo detection of tau fibrils and amyloid β aggregates with luminescent conjugated oligothiophenes and multiphoton microscopy

(2019) Maria Calvo-Rodriguez et al.   Acta Neuropathologica Communications

Additive-color multi-harmonic generation microscopy for simultaneous label-free differentiation of plaques, tangles, and neuronal axons

(2019) Sandeep Chakraborty et al.   Biomedical Optics Express

Imaging through Nonlinear Metalens Using Second Harmonic Generation

(2018) Christian Schlickriede et al.   ADVANCED MATERIALS

Monitoring of Alzheimer's Amyloid-β Peptide Aggregation via Fluorescence Correlation Spectroscopy and Total Internal Reflection Microscopy

(2018) Jüri Jarvet et al.   BIOPHYSICAL JOURNAL

Improved axial point spread function in a two-frequency laser scanning confocal fluorescence microscope

(2018) Jheng-Syong Wu et al.   JOURNAL OF BIOMEDICAL OPTICS

Near-infrared Fluorescence Ocular Imaging (NIRFOI) of Alzheimer’s Disease

(2018) Jian Yang et al.   MOLECULAR IMAGING AND BIOLOGY

In Vivo Near-Infrared Two-Photon Imaging of Amyloid Plaques in Deep Brain of Alzheimer’s Disease Mouse Model

(2018) Congping Chen et al.   ACS Chemical Neuroscience

Efficient Near-Infrared In Vivo Imaging of Amyoid-β Deposits in Alzheimer's Disease Mouse Models

(2018) Anke Schmidt et al.   JOURNAL OF ALZHEIMERS DISEASE

Highly Selective and Fast Diagnosis of Alzheimer's Disease Hallmark Lesions using Congo Red in Isopropyl Alcoholic Solution

(2018) Ana Navarro et al.   JOURNAL OF ALZHEIMERS DISEASE

Noninvasive 40-Hz light flicker to recruit microglia and reduce amyloid beta load

(2018) Annabelle C. Singer et al.   Nature Protocols

Label-free imaging of amyloid plaques in Alzheimer’s disease with stimulated Raman scattering microscopy

(2018) Minbiao Ji et al.   Science Advances

Recent advances in linear and non-linear Raman spectroscopy. Part XI

(2017) Laurence A. Nafie   JOURNAL OF RAMAN SPECTROSCOPY

Label-free imaging of amyloids using their intrinsic linear and nonlinear optical properties

(2017) Patrik K. Johansson et al.   Biomedical Optics Express

Meta-analysis of synaptic pathology in Alzheimer's disease reveals selective molecular vesicular machinery vulnerability

(2016) Martijn C. de Wilde et al.   Alzheimers & Dementia

Microglia contributes to plaque growth by cell death due to uptake of amyloid β in the brain of Alzheimer's disease mouse model

(2016) Sung Hoon Baik et al.   GLIA

Nonlinear optical microscopy for label-free detection of gastrointestinal neuroendocrine tumors

(2016) Lianhuang Li et al.   LASERS IN MEDICAL SCIENCE

Gamma frequency entrainment attenuates amyloid load and modifies microglia

(2016) Hannah F. Iaccarino et al.   NATURE

The amyloid-beta forming tripeptide cleavage mechanism of γ-secretase

(2016) David M Bolduc et al.   eLife

Label-free imaging and quantitative chemical analysis of Alzheimer’s disease brain samples with multimodal multiphoton nonlinear optical microspectroscopy

(2015) Jang Hyuk Lee et al.   JOURNAL OF BIOMEDICAL OPTICS

Nonlinear optical imaging of single plasmonic nanoparticles with 30 nm resolution

(2015) Anke Horneber et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Near-infrared fluorescence molecular imaging of amyloid beta species and monitoring therapy in animal models of Alzheimer’s disease

(2015) Xueli Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Plaque-associated lipids in Alzheimer’s diseased brain tissue visualized by nonlinear microscopy

(2015) Juris Kiskis et al.   Scientific Reports

Genomic mosaicism with increased amyloid precursor protein (APP) gene copy number in single neurons from sporadic Alzheimer's disease brains

(2015) Diane M Bushman et al.   eLife

Label-free real-time imaging of myelination in theXenopus laevistadpole byin vivostimulated Raman scattering microscopy

(2014) Chun-Rui Hu et al.   JOURNAL OF BIOMEDICAL OPTICS

Photodynamic therapy by in situ nonlinear photon conversion

(2014) A. V. Kachynski et al.   Nature Photonics

Modern Raman Imaging: Vibrational Spectroscopy on the Micrometer and Nanometer Scales

(2013) Lothar Opilik et al.   Annual Review of Analytical Chemistry

Multiphoton absorption in amyloid protein fibres

(2013) Piotr Hanczyc et al.   Nature Photonics

LVQ-SVM based CAD tool applied to structural MRI for the diagnosis of the Alzheimer’s disease

(2013) Andrés Ortiz et al.   PATTERN RECOGNITION LETTERS

Retinal vascular biomarkers for early detection and monitoring of Alzheimer’s disease

(2013) S Frost et al.   Translational Psychiatry

Amyloid-β oligomer detection by ELISA in cerebrospinal fluid and brain tissue

(2012) Kim A. Bruggink et al.   ANALYTICAL BIOCHEMISTRY

Label-free methods for probing the interaction of clioquinol with amyloid-β

(2012) Xin Ran Cheng et al.   Analytical Methods

A two-photon fluorescent probe for amyloid-β plaques in living mice

(2012) Cheol Ho Heo et al.   CHEMICAL COMMUNICATIONS

Advances on Alzheimer′s Disease With Neuroimaging*

(2012) Yong HE   PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS

Long-Term In Vivo Imaging of  -Amyloid Plaque Appearance and Growth in a Mouse Model of Cerebral  -Amyloidosis

(2011) J. K. Hefendehl et al.   JOURNAL OF NEUROSCIENCE

Repeatable target localization for long-term in vivo imaging of mice with 2-photon microscopy

(2011) Jasmin K. Hefendehl et al.   JOURNAL OF NEUROSCIENCE METHODS

RNAi screening for fat regulatory genes with SRS microscopy

(2011) Meng C Wang et al.   NATURE METHODS

Amyloid β oligomers induce Ca2+ dysregulation and neuronal death through activation of ionotropic glutamate receptors

(2010) Elena Alberdi et al.   CELL CALCIUM

Multimodal CARS microscopy determination of the impact of diet on macrophage infiltration and lipid accumulation on plaque formation in ApoE-deficient mice

(2010) Ryan S. Lim et al.   JOURNAL OF LIPID RESEARCH

The use of laser scanning confocal microscopy (LSCM) in materials science

(2010) D.B. HOVIS et al.   JOURNAL OF MICROSCOPY

Rapid and efficient screening of Alzheimer's disease β-amyloid inhibitors using label-free gold nanoparticles

(2010) Jie Geng et al.   Molecular BioSystems

Identification of amyloid plaques in retinas from Alzheimer's patients and noninvasive in vivo optical imaging of retinal plaques in a mouse model

(2010) Maya Koronyo-Hamaoui et al.   NEUROIMAGE

Multiphoton in vivo imaging of amyloid in animal models of Alzheimer’s disease

(2010) Jinghui Dong et al.   NEUROPHARMACOLOGY

Biophotonic probing of macromolecular transformations during apoptosis

(2010) A. Pliss et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Abnormal Cortical Networks in Mild Cognitive Impairment and Alzheimer's Disease

(2010) Zhijun Yao et al.   PLoS Computational Biology

Bioconjugation of barium titanate nanocrystals with immunoglobulin G antibody for second harmonic radiation imaging probes

(2009) Chia-Lung Hsieh et al.   BIOMATERIALS

Characterizing the Appearance and Growth of Amyloid Plaques in APP/PS1 Mice

(2009) P. Yan et al.   JOURNAL OF NEUROSCIENCE

Design, Synthesis, and Testing of Difluoroboron-Derivatized Curcumins as Near-Infrared Probes for in Vivo Detection of Amyloid-β Deposits

(2009) Chongzhao Ran et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Optical visualization of Alzheimer’s pathology via multiphoton-excited intrinsic fluorescence and second harmonic generation

(2009) Alex C. Kwan et al.   OPTICS EXPRESS

Optimal parameters for near infrared fluorescence imaging of amyloid plaques in Alzheimer's disease mouse models

(2009) S B Raymond et al.   PHYSICS IN MEDICINE AND BIOLOGY

Near-field second-harmonic generation in single gold nanoparticles

(2008) M. Zavelani-Rossi et al.   APPLIED PHYSICS LETTERS

Smart optical probes for near-infrared fluorescence imaging of Alzheimer’s disease pathology

(2008) Scott B. Raymond et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

In vivo imaging of cellular structures in Caenorhabditis elegans by combined TPEF, SHG and THG microscopy

(2008) E. J. GUALDA et al.   JOURNAL OF MICROSCOPY

Recent advances in linear and nonlinear Raman spectroscopy II

(2008) W. Kiefer   JOURNAL OF RAMAN SPECTROSCOPY

Rapid appearance and local toxicity of amyloid-β plaques in a mouse model of Alzheimer’s disease

(2008) Melanie Meyer-Luehmann et al.   NATURE

Label-Free Biomedical Imaging with High Sensitivity by Stimulated Raman Scattering Microscopy

(2008) Christian W. Freudiger et al.   SCIENCE