Impairment of neuronal mitochondrial function by l-DOPA in the absence of oxygen-dependent auto-oxidation and oxidative cell damage

Randomized Delayed-Start Trial of Levodopa in Parkinson’s Disease

(2019) Constant V.M. Verschuur et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Dominant Role of Oxygen in Modulating the Chemical Evolution Pathways of Tyrosine in Peptides: Dityrosine or Melanin

(2019) Xiaokang Ren et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype

(2019) Daehwan Kim et al.   NATURE BIOTECHNOLOGY

L-DOPA causes mitochondrial dysfunction in vitro: A novel mechanism of L-DOPA toxicity uncovered

(2019) Steven Giannopoulos et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Mitochondrial calcium imbalance in Parkinson’s disease

(2018) Marthe H.R. Ludtmann et al.   NEUROSCIENCE LETTERS

The NAD+ Precursor Nicotinamide Riboside Rescues Mitochondrial Defects and Neuronal Loss in iPSC and Fly Models of Parkinson’s Disease

(2018) David C. Schöndorf et al.   Cell Reports

Compatibility study between antiparkinsonian drug Levodopa and excipients by FTIR spectroscopy, X-ray diffraction and thermal analysis

(2017) Ionut Ledeti et al.   JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY

Analysis of mitochondrial metabolism in situ : Combining stable isotope labeling with selective permeabilization

(2017) Yannic Nonnenmacher et al.   METABOLIC ENGINEERING

Calcium Channel Antagonists as Disease-Modifying Therapy for Parkinson’s Disease: Therapeutic Rationale and Current Status

(2016) Tara Swart et al.   CNS DRUGS

Converging roles of ion channels, calcium, metabolic stress, and activity pattern ofSubstantia nigradopaminergic neurons in health and Parkinson's disease

(2016) Johanna Duda et al.   JOURNAL OF NEUROCHEMISTRY

Bioenergetics and redox adaptations of astrocytes to neuronal activity

(2016) Juan P. Bolaños   JOURNAL OF NEUROCHEMISTRY

Melanin synthesis under oxygen pressure

(2016) Erika Soares Bronze-Uhle et al.   POLYMER INTERNATIONAL

Regulation of rDNA transcription in response to growth factors, nutrients and energy

(2015) Eric P. Kusnadi et al.   GENE

PARP-1 involvement in neurodegeneration: A focus on Alzheimer’s and Parkinson’s diseases

(2015) Sara Martire et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Normal substantia nigra patients treated with levodopa – Clinical, therapeutic and pathological observations

(2015) Ali H. Rajput et al.   PARKINSONISM & RELATED DISORDERS

A mitochondrial UPR-mediated metabolic checkpoint regulates hematopoietic stem cell aging

(2015) M. Mohrin et al.   SCIENCE

Cell-based assays for Parkinson's disease using differentiated human LUHMES cells

(2014) Xiao-min Zhang et al.   ACTA PHARMACOLOGICA SINICA

DOSE: an R/Bioconductor package for disease ontology semantic and enrichment analysis

(2014) Guangchuang Yu et al.   BIOINFORMATICS

Proteome analysis reveals roles of L-DOPA in response to oxidative stress in neurons

(2014) Mohammad-Saeid Jami et al.   BMC NEUROSCIENCE

Pharmacological Treatment of Parkinson Disease

(2014) Barbara S. Connolly et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Pathview: an R/Bioconductor package for pathway-based data integration and visualization

(2013) Weijun Luo et al.   BIOINFORMATICS

Ursocholanic acid rescues mitochondrial function in common forms of familial Parkinson’s disease

(2013) Heather Mortiboys et al.   BRAIN

Complexity of dopamine metabolism

(2013) Johannes Meiser et al.   Cell Communication and Signaling

Reductive glutamine metabolism is a function of the α-ketoglutarate to citrate ratio in cells

(2013) Sarah-Maria Fendt et al.   Nature Communications

Protective Effects of L-Dopa and Carbidopa Combined Treatments on Human Catecholaminergic Cells

(2012) Monica Colamartino et al.   DNA AND CELL BIOLOGY

Dopamine Oxidation and Autophagy

(2012) Patricia Muñoz et al.   Parkinsons Disease

l-DOPA is incorporated into brain proteins of patients treated for Parkinson's disease, inducing toxicity in human neuroblastoma cells in vitro

(2011) Sandra W. Chan et al.   EXPERIMENTAL NEUROLOGY

Rapid, complete and large-scale generation of post-mitotic neurons from the human LUHMES cell line

(2011) Diana Scholz et al.   JOURNAL OF NEUROCHEMISTRY

A review of PARP inhibitors: from bench to bedside

(2010) C. Underhill et al.   ANNALS OF ONCOLOGY

Preventing NAD+ Depletion Protects Neurons against Excitotoxicity

(2010) Dong Liu et al.   Annals of the New York Academy of Sciences

Radical sequestration by protein-bound 3,4-dihydroxyphenylalanine

(2010) Michelle Nelson et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Mechanisms of L-DOPA-induced cytotoxicity in rat adrenal pheochromocytoma cells: implication of oxidative stress-related kinases and cyclic AMP

(2010) C.M. Jin et al.   NEUROSCIENCE

MetaboliteDetector: Comprehensive Analysis Tool for Targeted and Nontargeted GC/MS Based Metabolome Analysis

(2009) Karsten Hiller et al.   ANALYTICAL CHEMISTRY

Regulation of mitochondrial dehydrogenases by calcium ions

(2009) Richard M. Denton   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Phosphorus and proton magnetic resonance spectroscopy demonstrates mitochondrial dysfunction in early and advanced Parkinson's disease

(2009) Elke Hattingen et al.   BRAIN

Neuroprotective effect of l-dopa on dopaminergic neurons is comparable to pramipexol in MPTP-treated animal model of Parkinson’s disease: a direct comparison study

(2009) Jin Young Shin et al.   JOURNAL OF NEUROCHEMISTRY

PINK1-Associated Parkinson's Disease Is Caused by Neuronal Vulnerability to Calcium-Induced Cell Death

(2009) Sonia Gandhi et al.   MOLECULAR CELL

The Sanger FASTQ file format for sequences with quality scores, and the Solexa/Illumina FASTQ variants

(2009) Peter J. A. Cock et al.   NUCLEIC ACIDS RESEARCH

AMP-activated protein kinase adapts rRNA synthesis to cellular energy supply

(2009) S. Hoppe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A review of Parkinson's disease

(2008) C. A. Davie   BRITISH MEDICAL BULLETIN

Calcium Homeostasis Is Dysregulated in Parkinsonian Patients With l-DOPA-Induced Dyskinesias

(2008) Fabio Blandini et al.   CLINICAL NEUROPHARMACOLOGY

Parkinson's disease: clinical features and diagnosis

(2008) J Jankovic   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

The clinical relevance of levodopa toxicity in the treatment of Parkinson's disease

(2008) Anthony H.V. Schapira   MOVEMENT DISORDERS

Neutral red uptake assay for the estimation of cell viability/cytotoxicity

(2008) Guillermo Repetto et al.   Nature Protocols

The PINK1/Parkin pathway regulates mitochondrial morphology

(2008) A. C. Poole et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA