Of Screening, Stratification, and Scores

Validation of an Integrated Risk Tool, Including Polygenic Risk Score, for Atherosclerotic Cardiovascular Disease in Multiple Ethnicities and Ancestries

(2021) Michael E. Weale et al.   AMERICAN JOURNAL OF CARDIOLOGY

Ethical Issues in Consent for the Reuse of Data in Health Data Platforms

(2021) Alex McKeown et al.   SCIENCE AND ENGINEERING ETHICS

Women’s Views on Multifactorial Breast Cancer Risk Assessment and Risk-Stratified Screening: A Population-Based Survey from Four Provinces in Canada

(2021) Cynthia Mbuya Bienge et al.   Journal of Personalized Medicine

Reduced cancer risk from healthier lifestyle

(2021) Brian Køster   ACTA ONCOLOGICA

Will polygenic risk scores for cancer ever be clinically useful?

(2021) Amit Sud et al.   npj Precision Oncology

Personalized Risk Assessment for Prevention and Early Detection of Breast Cancer: Integration and Implementation (PERSPECTIVE I&I)

(2021) Jennifer Brooks et al.   Journal of Personalized Medicine

Population-based Genetic Testing for Precision Prevention

(2020) Olivia Evans et al.   Cancer Prevention Research

Ancestry-specific hereditary cancer panel yields: Moving toward more personalized risk assessment

(2020) Maegan E. Roberts et al.   Journal of Genetic Counseling

The challenge of early detection in cancer

(2020) Nora Pashayan et al.   SCIENCE

Polygenic risk scores: from research tools to clinical instruments

(2020) Cathryn M. Lewis et al.   Genome Medicine

Tutorial: a guide to performing polygenic risk score analyses

(2020) Shing Wan Choi et al.   Nature Protocols

Personalized early detection and prevention of breast cancer: ENVISION consensus statement

(2020) Nora Pashayan et al.   Nature Reviews Clinical Oncology

European polygenic risk score for prediction of breast cancer shows similar performance in Asian women

(2020) Weang-Kee Ho et al.   Nature Communications

Biobanks in the era of big data: objectives, challenges, perspectives, and innovations for predictive, preventive, and personalised medicine

(2020) Judita Kinkorová et al.   EPMA Journal

Personalizing Breast Cancer Screening Based on Polygenic Risk and Family History

(2020) Jeroen J van den Broek et al.   JNCI-Journal of the National Cancer Institute

How to fix the GDPR's frustration of global biomedical research

(2020) Jasper Bovenberg et al.   SCIENCE

Improving the trans-ancestry portability of polygenic risk scores by prioritizing variants in predicted cell-type-specific regulatory elements

(2020) Tiffany Amariuta et al.   NATURE GENETICS

BOADICEA: a comprehensive breast cancer risk prediction model incorporating genetic and nongenetic risk factors

(2019) Andrew Lee et al.   GENETICS IN MEDICINE

Risk Stratification in Differentiated Thyroid Cancer: From Detection to Final Follow-up

(2019) R Michael Tuttle et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

A response to “Personalised medicine and population health: breast and ovarian cancer”

(2019) Antonis Antoniou et al.   HUMAN GENETICS

Defining and Achieving Health Equity in Genomic Medicine

(2019) Sonya Jooma et al.   ETHNICITY & DISEASE

A systematic review and quality assessment of individualised breast cancer risk prediction models

(2019) Javier Louro et al.   BRITISH JOURNAL OF CANCER

A duty to recontact in genetics: context matters

(2019) Noor A. A. Giesbertz et al.   NATURE REVIEWS GENETICS

Perspective: The Clinical Use of Polygenic Risk Scores: Race, Ethnicity, and Health Disparities

(2019) Megan C. Roberts et al.   ETHNICITY & DISEASE

Implementing Risk Stratification in Primary Care: Challenges and Strategies

(2019) Jesse Wagner et al.   Journal of the American Board of Family Medicine

Breast Cancer Screening and Diagnosis: A Synopsis of the European Breast Guidelines

(2019) Holger J. Schünemann et al.   ANNALS OF INTERNAL MEDICINE

Cost-Effectiveness of Cancer Screening: Health and Costs in Life Years Gained

(2019) Svetlana Ratushnyak et al.   AMERICAN JOURNAL OF PREVENTIVE MEDICINE

Polygenic risk-tailored screening for prostate cancer: A benefit–harm and cost-effectiveness modelling study

(2019) Tom Callender et al.   PLOS MEDICINE

A Computational Statistics Approach to Evaluate Blood Biomarkers for Breast Cancer Risk Stratification

(2019) Kaan Oktay et al.   Hormones & Cancer

Introducing genomics into cancer care

(2018) S. Hill   BRITISH JOURNAL OF SURGERY

Epigenome-based cancer risk prediction: rationale, opportunities and challenges

(2018) Martin Widschwendter et al.   Nature Reviews Clinical Oncology

Cost-effectiveness and Benefit-to-Harm Ratio of Risk-Stratified Screening for Breast Cancer

(2018) Nora Pashayan et al.   JAMA Oncology

Prevalence of Variant Reclassification Following Hereditary Cancer Genetic Testing

(2018) Jacqueline Mersch et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Polygenic risk score for schizophrenia is more strongly associated with ancestry than with schizophrenia

(2018) David Curtis   PSYCHIATRIC GENETICS

Addition of a polygenic risk score, mammographic density, and endogenous hormones to existing breast cancer risk prediction models: A nested case–control study

(2018) Xuehong Zhang et al.   PLOS MEDICINE

The clinical imperative for inclusivity: Race, ethnicity, and ancestry (REA) in genomics

(2018) Alice B. Popejoy et al.   HUMAN MUTATION

Personalized Risk-Stratified Cancer Follow-Up Care: Its Potential for Healthier Survivors, Happier Clinicians, and Lower Costs

(2018) Deborah K Mayer et al.   JNCI-Journal of the National Cancer Institute

Recontacting in clinical practice: the views and expectations of patients in the United Kingdom

(2017) Daniele Carrieri et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Risk of breast cancer after a diagnosis of ovarian cancer in BRCA mutation carriers: Is preventive mastectomy warranted?

(2017) Jacob McGee et al.   GYNECOLOGIC ONCOLOGY

Defining Population Health Management: A Scoping Review of the Literature

(2017) Betty M. Steenkamer et al.   Population Health Management

Data, data everywhere: the challenges of personalised medicine

(2017) Stephen Armstrong   BMJ-British Medical Journal

Data, data everywhere: the challenges of personalised medicine

(2017) Stephen Armstrong   BMJ-British Medical Journal

The Interaction between Genetic Ancestry and Breast Cancer Risk Factors among Hispanic Women: The Breast Cancer Health Disparities Study

(2016) Lisa M. Hines et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Why take part in personalised cancer research? Patients’ genetic misconception, genetic responsibility and incomprehension of stratification-an empirical-ethical examination

(2016) J. Perry et al.   EUROPEAN JOURNAL OF CANCER CARE

A proposed national research and development agenda for population health informatics: summary recommendations from a national expert workshop

(2016) Hadi Kharrazi et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

Active surveillance for intermediate-risk prostate cancer

(2016) M A Dall'Era et al.   PROSTATE CANCER AND PROSTATIC DISEASES

Reducing overdiagnosis by polygenic risk-stratified screening: findings from the Finnish section of the ERSPC

(2015) Nora Pashayan et al.   BRITISH JOURNAL OF CANCER

Big Data in medical research and EU data protection law: challenges to the consent or anonymise approach

(2015) Menno Mostert et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Explicit Modeling of Ancestry Improves Polygenic Risk Scores and BLUP Prediction

(2015) Chia-Yen Chen et al.   GENETIC EPIDEMIOLOGY

Implications of polygenic risk-stratified screening for prostate cancer on overdiagnosis

(2015) Nora Pashayan et al.   GENETICS IN MEDICINE

Prediction of Breast Cancer Risk Based on Profiling With Common Genetic Variants

(2015) Nasim Mavaddat et al.   JNCI-Journal of the National Cancer Institute

Active surveillance for low-risk prostate cancer: Need for intervention and survival at 10 years

(2015) Mark A. Preston et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Prediction of Breast Cancer Risk Based on Profiling With Common Genetic Variants

(2015) Nasim Mavaddat et al.   JNCI-Journal of the National Cancer Institute

Delivering precision medicine in oncology today and in future—the promise and challenges of personalised cancer medicine: a position paper by the European Society for Medical Oncology (ESMO)

(2014) F. Ciardiello et al.   ANNALS OF ONCOLOGY

The ethical framing of personalized medicine

(2014) Yann Joly et al.   Current Opinion in Allergy and Clinical Immunology

FDA Regulation of Mobile Health Technologies

(2014) Nathan G. Cortez et al.   NEW ENGLAND JOURNAL OF MEDICINE

BOADICEA breast cancer risk prediction model: updates to cancer incidences, tumour pathology and web interface

(2013) A J Lee et al.   BRITISH JOURNAL OF CANCER

The benefits and harms of breast cancer screening: an independent review

(2013) M G Marmot et al.   BRITISH JOURNAL OF CANCER

Health research and systems’ governance are at risk: should the right to data protection override health?

(2013) C T Di Iorio et al.   JOURNAL OF MEDICAL ETHICS

The prostate cancer risk stratification (ProCaRS) project: Recursive partitioning risk stratification analysis

(2013) George Rodrigues et al.   RADIOTHERAPY AND ONCOLOGY

Risk stratification in prostate cancer screening

(2012) Monique J. Roobol et al.   Nature Reviews Urology

The future of technologies for personalised medicine

(2012) Alison Harvey et al.   New Biotechnology

A national clinical decision support infrastructure to enable the widespread and consistent practice of genomic and personalized medicine

(2009) Kensaku Kawamoto et al.   BMC Medical Informatics and Decision Making

Revisting wilson and Jungner in the genomic age: a review of screening criteria over the past 40 years

(2008) Anne Andermann   BULLETIN OF THE WORLD HEALTH ORGANIZATION

Maximising benefit and minimising harm of screening

(2008) J A M Gray et al.   BMJ-British Medical Journal