Validation of an Integrated Risk Tool, Including Polygenic Risk Score, for Atherosclerotic Cardiovascular Disease in Multiple Ethnicities and Ancestries

Predictive Accuracy of a Polygenic Risk Score–Enhanced Prediction Model vs a Clinical Risk Score for Coronary Artery Disease

(2020) Joshua Elliott et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Do Polygenic Risk Scores Improve Patient Selection for Prevention of Coronary Artery Disease?

(2020) Sadiya S. Khan et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Predictive Accuracy of a Polygenic Risk Score Compared With a Clinical Risk Score for Incident Coronary Heart Disease

(2020) Jonathan D. Mosley et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Predictive Utility of Polygenic Risk Scores for Coronary Heart Disease in Three Major Racial and Ethnic Groups

(2020) Ozan Dikilitas et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Polygenic and clinical risk scores and their impact on age at onset and prediction of cardiometabolic diseases and common cancers

(2020) Nina Mars et al.   NATURE MEDICINE

What is ancestry?

(2020) Iain Mathieson et al.   PLoS Genetics

Theoretical and empirical quantification of the accuracy of polygenic scores in ancestry divergent populations

(2020) Ying Wang et al.   Nature Communications

Clinical use of current polygenic risk scores may exacerbate health disparities

(2019) Alicia R. Martin et al.   NATURE GENETICS

2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease

(2019) Donna K. Arnett et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Analysis of polygenic risk score usage and performance in diverse human populations

(2019) L. Duncan et al.   Nature Communications

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

(2018) Rainer Malik et al.   NATURE GENETICS

Genomic Risk Prediction of Coronary Artery Disease in 480,000 Adults

(2018) Michael Inouye et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The UK Biobank resource with deep phenotyping and genomic data

(2018) Clare Bycroft et al.   NATURE

Genetics of coronary artery disease: discovery, biology and clinical translation

(2017) Amit V. Khera et al.   NATURE REVIEWS GENETICS

A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease

(2015) Majid Nikpay et al.   NATURE GENETICS

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

(2015) Cathie Sudlow et al.   PLOS MEDICINE

2013 ACC/AHA Guideline on the Assessment of Cardiovascular Risk

(2013) David C. Goff et al.   CIRCULATION