Synchronous effects of targeted mitochondrial complex I inhibitors on tumor and immune cells abrogate melanoma progression

Metabolic Symbiosis in Chemoresistance: Refocusing the Role of Aerobic Glycolysis

(2020) Lisi Ma et al.   Frontiers in Oncology

Macrophage-Released Pyrimidines Inhibit Gemcitabine Therapy in Pancreatic Cancer

(2019) Christopher J. Halbrook et al.   Cell Metabolism

Role and Therapeutic Targeting of the PI3K/Akt/mTOR Signaling Pathway in Skin Cancer: A Review of Current Status and Future Trends on Natural and Synthetic Agents Therapy

(2019) Chamcheu et al.   Cells

Aerobic Glycolysis Controls Myeloid-Derived Suppressor Cells and Tumor Immunity via a Specific CEBPB Isoform in Triple-Negative Breast Cancer

(2018) Wei Li et al.   Cell Metabolism

An inhibitor of oxidative phosphorylation exploits cancer vulnerability

(2018) Jennifer R. Molina et al.   NATURE MEDICINE

FoxO transcription factors in cancer metabolism

(2018) Raj Kumar Yadav et al.   SEMINARS IN CANCER BIOLOGY

Oncogenic HSP60 regulates mitochondrial oxidative phosphorylation to support Erk1/2 activation during pancreatic cancer cell growth

(2018) Chao Zhou et al.   Cell Death & Disease

CellProfiler 3.0: Next-generation image processing for biology

(2018) Claire McQuin et al.   PLOS BIOLOGY

A review of the basics of mitochondrial bioenergetics, metabolism, and related signaling pathways in cancer cells: Therapeutic targeting of tumor mitochondria with lipophilic cationic compounds

(2018) Balaraman Kalyanaraman et al.   Redox Biology

A Mitochondrial Checkpoint in Autoimmune Disease

(2018) Cornelia M. Weyand et al.   Cell Metabolism

Mitochondria-targeted drugs stimulate mitophagy and abrogate colon cancer cell proliferation

(2018) Kathleen A. Boyle et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting T Cell Metabolism for Improvement of Cancer Immunotherapy

(2018) Thibault Le Bourgeois et al.   Frontiers in Oncology

Targeting metabolic reprogramming in KRAS-driven cancers

(2017) Kenji Kawada et al.   International Journal of Clinical Oncology

Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity

(2017) Kenji Chamoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glycolysis regulates the expansion of myeloid-derived suppressor cells in tumor-bearing hosts through prevention of ROS-mediated apoptosis

(2017) Shiou-Ling Jian et al.   Cell Death & Disease

Cancer treatment and survivorship statistics, 2016

(2016) Kimberly D. Miller et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Mitochondria-Targeted Analogues of Metformin Exhibit Enhanced Antiproliferative and Radiosensitizing Effects in Pancreatic Cancer Cells

(2016) Gang Cheng et al.   CANCER RESEARCH

Mitochondrial Membrane Potential Identifies Cells with Enhanced Stemness for Cellular Therapy

(2016) Madhusudhanan Sukumar et al.   Cell Metabolism

Blocking Indolamine-2,3-Dioxygenase Rebound Immune Suppression Boosts Antitumor Effects of Radio-Immunotherapy in Murine Models and Spontaneous Canine Malignancies

(2016) A. M. Monjazeb et al.   CLINICAL CANCER RESEARCH

Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion

(2016) Cristovão M. Sousa et al.   NATURE

Antiproliferative effects of mitochondria-targeted cationic antioxidants and analogs: Role of mitochondrial bioenergetics and energy-sensing mechanism

(2015) Gang Cheng et al.   CANCER LETTERS

MYC/PGC-1α Balance Determines the Metabolic Phenotype and Plasticity of Pancreatic Cancer Stem Cells

(2015) Patricia Sancho et al.   Cell Metabolism

The PI3K/Akt Pathway Regulates Oxygen Metabolism via Pyruvate Dehydrogenase (PDH)-E1  Phosphorylation

(2015) G. J. Cerniglia et al.   MOLECULAR CANCER THERAPEUTICS

Amino acid auxotrophy as a system of immunological control nodes

(2015) Peter J Murray   NATURE IMMUNOLOGY

A core of kinase-regulated interactomes defines the neoplastic MDSC lineage

(2015) Maria Gato-Cañas et al.   Oncotarget

A comparative analysis of inhibitors of the glycolysis pathway in breast and ovarian cancer cell line models

(2015) Chrysi Xintaropoulou et al.   Oncotarget

Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies

(2015) F. Hossain et al.   Cancer Immunology Research

Effects of metformin and other biguanides on oxidative phosphorylation in mitochondria

(2014) Hannah R. Bridges et al.   BIOCHEMICAL JOURNAL

Profiling and targeting of cellular bioenergetics: inhibition of pancreatic cancer cell proliferation

(2014) G Cheng et al.   BRITISH JOURNAL OF CANCER

Bioenergetic modulation with dichloroacetate reduces the growth of melanoma cells and potentiates their response to BRAFV600E inhibition

(2014) Cecilie Abildgaard et al.   Journal of Translational Medicine

Optimal Management of Metastatic Melanoma: Current Strategies and Future Directions

(2013) Marta Batus et al.   AMERICAN JOURNAL OF CLINICAL DERMATOLOGY

Mitochondria-targeted vitamin E analogs inhibit breast cancer cell energy metabolism and promote cell death

(2013) Gang Cheng et al.   BMC CANCER

Mitochondria Are Required for Antigen-Specific T Cell Activation through Reactive Oxygen Species Signaling

(2013) Laura A. Sena et al.   IMMUNITY

Mitochondria-Targeted Drugs Synergize with 2-Deoxyglucose to Trigger Breast Cancer Cell Death

(2012) G. Cheng et al.   CANCER RESEARCH

A Landscape of Driver Mutations in Melanoma

(2012) Eran Hodis et al.   CELL

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

From delocalized lipophilic cations to hypoxia: Blocking tumor cell mitochondrial function leads to therapeutic gain with glycolytic inhibitors

(2008) Metin Kurtoglu et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Is Akt the “Warburg kinase”?—Akt-energy metabolism interactions and oncogenesis

(2008) R. Brooks Robey et al.   SEMINARS IN CANCER BIOLOGY

Rotenone-Induced Toxicity is Mediated by Rho-GTPases in Hippocampal Neurons

(2008) Monica Sanchez et al.   TOXICOLOGICAL SCIENCES

Biguanide-induced mitochondrial dysfunction yields increased lactate production and cytotoxicity of aerobically-poised HepG2 cells and human hepatocytes in vitro

(2008) James A. Dykens et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY