Elucidation of the Mechanism Underlying the Anti-Inflammatory Properties of (S)-(+)-Carvone Identifies a Novel Class of Sirtuin-1 Activators in a Murine Macrophage Cell Line

Oxidative Stress and Inflammation Biomarker Expression in Obstructive Sleep Apnea Patients

(2021) Antonino Maniaci et al.   Journal of Clinical Medicine

Standardised comparison of limonene-derived monoterpenes identifies structural determinants of anti-inflammatory activity

(2020) Cátia Sousa et al.   Scientific Reports

Cardioprotective Effects of Sirtuin-1 and Its Downstream Effectors

(2020) Milton Packer   Circulation-Heart Failure

The importance of determining circadian parameters in pharmacological studies

(2019) Laetitia Gaspar et al.   BRITISH JOURNAL OF PHARMACOLOGY

Dichotomous Sirtuins: Implications for Drug Discovery in Neurodegenerative and Cardiometabolic Diseases

(2019) Pedro Gomes et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Anti-Inflammatory Effects of Resveratrol: Mechanistic Insights

(2018) Diego de Sá Coutinho et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Sirtuin activators and inhibitors: Promises, achievements, and challenges

(2018) Han Dai et al.   PHARMACOLOGY & THERAPEUTICS

Turning back time with emerging rejuvenation strategies

(2018) Salah Mahmoudi et al.   NATURE CELL BIOLOGY

BITC and S-Carvone Restrain High-Fat Diet-Induced Obesity and Ameliorate Hepatic Steatosis and Insulin Resistance

(2017) Sary Alsanea et al.   PHARMACEUTICAL RESEARCH

Inflammatory responses and inflammation-associated diseases in organs

(2017) Linlin Chen et al.   Oncotarget

Beneficial effect of carvone, a dietary monoterpene ameliorates hyperglycemia by regulating the key enzymes activities of carbohydrate metabolism in streptozotocin-induced diabetic rats

(2016) Udaiyar Muruganathan et al.   BIOMEDICINE & PHARMACOTHERAPY

Curcumin pretreatment attenuates inflammation and mitochondrial dysfunction in experimental stroke: The possible role of Sirt1 signaling

(2016) Yanping Miao et al.   BRAIN RESEARCH BULLETIN

Keeping the senescence secretome under control: Molecular reins on the senescence-associated secretory phenotype

(2016) Nicolas Malaquin et al.   EXPERIMENTAL GERONTOLOGY

Potential therapeutic targets for inflammation in toll-like receptor 4 (TLR4)-mediated signaling pathways

(2016) Anjali Roy et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Assessment of cell line competence for studies of pharmacological GPR30 modulation

(2016) Cátia Sousa et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Anti-Inflammatory Activity of Natural Products

(2016) Abdullatif Azab et al.   MOLECULES

Fisetin induces Sirt1 expression while inhibiting early adipogenesis in 3T3-L1 cells

(2015) Sang Chon Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Evaluation of the anti-inflammatory, anti-catabolic and pro-anabolic effects of E-caryophyllene, myrcene and limonene in a cell model of osteoarthritis

(2015) Ana Teresa Rufino et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

In Vitro Antioxidant Activity of S-Carvone Isolated from Zanthoxylum alatum

(2015) S. M. Sabir et al.   PHARMACEUTICAL CHEMISTRY JOURNAL

Anti-inflammatory and Chondroprotective Activity of (+)-α-Pinene: Structural and Enantiomeric Selectivity

(2014) Ana T. Rufino et al.   JOURNAL OF NATURAL PRODUCTS

Antagonistic crosstalk between NF-κB and SIRT1 in the regulation of inflammation and metabolic disorders

(2013) Anu Kauppinen et al.   CELLULAR SIGNALLING

Anti-inflammatory effects of the main constituents and epoxides derived from the essential oils obtained fromTagetes lucida, Cymbopogon citratus, Lippia albaandEucalyptus citriodora

(2013) J.C. Sepúlveda-Arias et al.   JOURNAL OF ESSENTIAL OIL RESEARCH

c-Jun, at the crossroad of the signaling network

(2011) Qinghang Meng et al.   Protein & Cell

Mammalian Sirtuins: Biological Insights and Disease Relevance

(2010) Marcia C. Haigis et al.   Annual Review of Pathology-Mechanisms of Disease

Inhibiting NF-κB activation by small molecules as a therapeutic strategy

(2010) Subash C. Gupta et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Inflammation 2010: New Adventures of an Old Flame

(2010) Ruslan Medzhitov   CELL

Posttranslational modifications of NF-κB: Another layer of regulation for NF-κB signaling pathway

(2010) Bo Huang et al.   CELLULAR SIGNALLING

c-Jun Controls Histone Modifications, NF- B Recruitment, and RNA Polymerase II Function To Activate the ccl2 Gene

(2008) S. Wolter et al.   MOLECULAR AND CELLULAR BIOLOGY