Cerebral Organoids Derived from a Parkinson’s Patient Exhibit Unique Pathogenesis from Chikungunya Virus Infection When Compared to a Non-Parkinson’s Patient

One-Stop Microfluidic Assembly of Human Brain Organoids To Model Prenatal Cannabis Exposure

(2020) Zheng Ao et al.   ANALYTICAL CHEMISTRY

Chikungunya virus evades antiviral CD8+ T cell responses to establish persistent infection in joint-associated tissues

(2020) Bennett J. Davenport et al.   JOURNAL OF VIROLOGY

Antibodies for Venezuelan Equine Encephalitis Virus Protect Embryoid Bodies from Chikungunya Virus

(2020) Emily M. Schultz et al.   Viruses-Basel

Bacterial, viral, and fungal infection‐related risk of Parkinson's disease: Meta‐analysis of cohort and case–control studies

(2020) Hui Wang et al.   Brain and Behavior

Serotonergic drugs inhibit CHIKV infection at different stages of the cell entry pathway

(2020) Ellen M. Bouma et al.   JOURNAL OF VIROLOGY

The Sox2 transcription factor binds RNA

(2020) Zachariah E. Holmes et al.   Nature Communications

Chikungunya Virus Infection Impairs the Function of Osteogenic Cells

(2020) Enakshi Roy et al.   mSphere

Midbrain Organoids: A New Tool to Investigate Parkinson’s Disease

(2020) Lisa Maria Smits et al.   Frontiers in Cell and Developmental Biology

Natural transmission of bat-like SARS-CoV-2PRRA variants in COVID-19 patients

(2020) Yik Chun Wong et al.   CLINICAL INFECTIOUS DISEASES

Modeling neoplastic disease with spheroids and organoids

(2020) Michele Zanoni et al.   Journal of Hematology & Oncology

Neurocognitive impacts of arbovirus infections

(2020) Marion Clé et al.   Journal of Neuroinflammation

The Past, Present and Future of Intestinal In Vitro Cell Systems for Drug Absorption Studies

(2020) Sonia Youhanna et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Nouvelle approche thérapeutique pour les rétinites pigmentaires

(2020) Olivier Goureau et al.   M S-MEDECINE SCIENCES

Reproducible generation of human midbrain organoids for in vitro modeling of Parkinson’s disease

(2020) Sarah Louise Nickels et al.   Stem Cell Research

Organoid Models of Tumor Immunology

(2020) Kanako Yuki et al.   TRENDS IN IMMUNOLOGY

Improving Therapeutic Interventions of Schizophrenia with Advances in Stem Cell Technology

(2020) José Andrés Espejo Oltra   Clinical Psychopharmacology and Neuroscience

Neurovascular Inflammaging in Health and Disease

(2020) Ádám Mészáros et al.   Cells

Genetic predispositions of Parkinson’s disease revealed in patient-derived brain cells

(2020) Jenne Tran et al.   npj Parkinsons Disease

Mesenchymal plasticity regulated by Prrx1 drives aggressive pancreatic cancer biology

(2020) Karin Feldmann et al.   GASTROENTEROLOGY

Reality check for organoids in neuroscience

(2020) Vivien Marx   NATURE METHODS

Rotavirus Infection and Cytopathogenesis in Human Biliary Organoids Potentially Recapitulate Biliary Atresia Development

(2020) Sunrui Chen et al.   mBio

Patient-Derived Midbrain Organoids to Explore the Molecular Basis of Parkinson's Disease

(2020) Benjamin Galet et al.   Frontiers in Neurology

Organoids to Study Intestinal Nutrient Transport, Drug Uptake and Metabolism – Update to the Human Model and Expansion of Applications

(2020) Tamara Zietek et al.   Frontiers in Bioengineering and Biotechnology

The Role of Chronic Inflammatory Bone and Joint Disorders in the Pathogenesis and Progression of Alzheimer's Disease

(2020) Robert A. Culibrk et al.   Frontiers in Aging Neuroscience

Inflammation, Infectious Triggers, and Parkinson's Disease

(2019) Elisa Caggiu et al.   Frontiers in Neurology

Chikungunya in Infants and Children: Is Pathogenesis Increasing?

(2019) Kelli Barr et al.   Viruses-Basel

Virus load and clinical features during the acute phase of Chikungunya infection in children

(2019) Siva Raghavendhar B. et al.   PLoS One

Chemokines and matrix metalloproteinases in cerebrospinal fluid of patients with central nervous system complications caused by varicella-zoster virus

(2019) Liza Lind et al.   Journal of Neuroinflammation

Human-Derived Brain Models: Windows Into Neuropsychiatric Disorders and Drug Therapies

(2019) Alexis Papariello et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

PD1+CCR2+CD8+ T Cells Infiltrate the Central Nervous System during Acute Japanese Encephalitis Virus Infection

(2019) Fang Zhang et al.   VIROLOGICA SINICA

Associations of acetylcholinesterase activity with depression and anxiety symptoms among adolescents growing up near pesticide spray sites

(2019) Jose R. Suarez-Lopez et al.   INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH

The effect of exposure to crude oil on the immune system. Health implications for people living near oil exploration activities

(2019) Pauline McLoone et al.   INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH

Mechanisms of hyperexcitability in Alzheimer’s disease hiPSC-derived neurons and cerebral organoids vs isogenic controls

(2019) Swagata Ghatak et al.   eLife

Neuroinflammation & pre-mature aging in the context of chronic HIV infection and drug abuse: Role of dysregulated autophagy

(2019) Ming-Lei Guo et al.   BRAIN RESEARCH

Th17 Lymphocytes Induce Neuronal Cell Death in a Human iPSC-Based Model of Parkinson’s Disease

(2018) Annika Sommer et al.   Cell Stem Cell

GBA-Associated Parkinson’s Disease and Other Synucleinopathies

(2018) Ziv Gan-Or et al.   Current Neurology and Neuroscience Reports

Potential relationships between chikungunya and depression: Solving the puzzle with key cytokines

(2018) Alfonso J. Rodríguez-Morales et al.   CYTOKINE

Manic Episode After a Chikungunya Virus Infection in a Bipolar Patient Previously Stabilized With Valproic Acid

(2018) Tiago Figueiredo et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Human tyrosine hydroxylase in Parkinson’s disease and in related disorders

(2018) Toshiharu Nagatsu et al.   JOURNAL OF NEURAL TRANSMISSION

Is Parkinson's Disease a Neurodevelopmental Disorder and Will Brain Organoids Help Us to Understand It?

(2018) Jens C. Schwamborn   STEM CELLS AND DEVELOPMENT

Comprehensive innate immune profiling of chikungunya virus infection in pediatric cases

(2018) Daniela Michlmayr et al.   Molecular Systems Biology

EBV reduces autophagy, intracellular ROS and mitochondria to impair monocyte survival and differentiation

(2018) M.S. Gilardini Montani et al.   Autophagy

Human Cardiac Organoids for Disease Modeling

(2018) Bramasta Nugraha et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Using Patient-Derived Induced Pluripotent Stem Cells to Identify Parkinson’s Disease-Relevant Phenotypes

(2018) S. L. Sison et al.   Current Neurology and Neuroscience Reports

Modelling human cardiac diseases with 3D organoid

(2018) Bramasta Nugraha et al.   EUROPEAN HEART JOURNAL

Subversion of the Heme Oxygenase-1 Antiviral Activity by Zika Virus

(2018) Chaker El Kalamouni et al.   Viruses-Basel

heme oxygenase-1 agonist CoPP suppresses influenza virus replication through IRF3-mediated generation of IFN-α/β

(2018) Lin-Lin Ma et al.   VIROLOGY

Zika virus: A public health threat

(2017) Shashi Sharma et al.   JOURNAL OF MEDICAL VIROLOGY

Chemokine Receptor Ccr7 Restricts Fatal West Nile Virus Encephalitis

(2017) Susana V. Bardina et al.   JOURNAL OF VIROLOGY

Cell diversity and network dynamics in photosensitive human brain organoids

(2017) Giorgia Quadrato et al.   NATURE

The Range of Neurological Complications in Chikungunya Fever

(2017) T. Cerny et al.   Neurocritical Care

Review: Astrocytes in Alzheimer's disease and other age-associated dementias: a supporting player with a central role

(2017) C. J. Garwood et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Defective synaptic connectivity and axonal neuropathology in a human iPSC-based model of familial Parkinson’s disease

(2017) Georgia Kouroupi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emerging arboviruses in Rio Grande do Sul, Brazil: Chikungunya and Zika outbreaks, 2014-2016

(2017) Tatiana Schäffer Gregianini et al.   REVIEWS IN MEDICAL VIROLOGY

Chikungunya virus infection with severe neurologic manifestations: report of four fatal cases

(2017) Priscilla Karen de Oliveira Sá et al.   Revista da Sociedade Brasileira de Medicina Tropical

Disease Modeling in Stem Cell-Derived 3D Organoid Systems

(2017) Devanjali Dutta et al.   TRENDS IN MOLECULAR MEDICINE

Derivation of Functional Human Astrocytes from Cerebral Organoids

(2017) Rômulo Sperduto Dezonne et al.   Scientific Reports

Tranylcypromine Causes Neurotoxicity and Represses BHC110/LSD1 in Human-Induced Pluripotent Stem Cell-Derived Cerebral Organoids Model

(2017) Jing Huang et al.   Frontiers in Neurology

Modeling Development and Disease with Organoids

(2016) Hans Clevers   CELL

The Human Serotonin Type 3 Receptor Gene (HTR3A-E) Allelic Variant Database

(2016) Jacopo Celli et al.   HUMAN MUTATION

Alpha synuclein and crystallin expression in human lens in Parkinson's disease

(2016) Alexa Klettner et al.   MOVEMENT DISORDERS

Molecular Features Underlying Neurodegeneration Identified through In Vitro Modeling of Genetically Diverse Parkinson’s Disease Patients

(2016) Lin Lin et al.   Cell Reports

Assessing Seasonal Risks for the Introduction and Mosquito-borne Spread of Zika Virus in Europe

(2016) Joacim Rocklöv et al.   EBioMedicine

Human heme oxygenase 1 is a potential host cell factor against dengue virus replication

(2016) Chin-Kai Tseng et al.   Scientific Reports

The immune system is limited by oxidative stress: Dietary selenium promotes optimal antioxidative status and greatest immune defense in pacu Piaractus mesopotamicus

(2015) Jaqueline D. Biller-Takahashi et al.   FISH & SHELLFISH IMMUNOLOGY

Cytokines as biomarkers of Crimean-Congo hemorrhagic fever

(2015) Anna Papa et al.   JOURNAL OF MEDICAL VIROLOGY

Serotonin Receptor Agonist 5-Nonyloxytryptamine Alters the Kinetics of Reovirus Cell Entry

(2015) Bernardo A. Mainou et al.   JOURNAL OF VIROLOGY

IFN-β inhibits T cells accumulation in the central nervous system by reducing the expression and activity of chemokines in experimental autoimmune encephalomyelitis

(2015) Wenjing Cheng et al.   MOLECULAR IMMUNOLOGY

Environmental Role in Influenza Virus Outbreaks

(2015) Harini Sooryanarain et al.   Annual Review of Animal Biosciences

Interference with the Autophagic Process as a Viral Strategy to Escape from the Immune Control: Lesson from Gamma Herpesviruses

(2015) Roberta Santarelli et al.   Journal of Immunology Research

Loss of the thyroid hormone-binding protein Crym renders striatal neurons more vulnerable to mutant huntingtin in Huntington's disease

(2014) Laetitia Francelle et al.   HUMAN MOLECULAR GENETICS

CCR5 Blockade Promotes M2 Macrophage Activation and Improves Locomotor Recovery After Spinal Cord Injury in Mice

(2014) Fengtao Li et al.   INFLAMMATION

Mouse models of alphavirus-induced inflammatory disease

(2014) A. Taylor et al.   JOURNAL OF GENERAL VIROLOGY

Hepatic HMOX1 Expression Positively Correlates with Bach-1 and miR-122 in Patients with HCV Mono and HIV/HCV Coinfection

(2014) Elżbieta Jabłonowska et al.   PLoS One

Neurocognitive Outcome of Children Exposed to Perinatal Mother-to-Child Chikungunya Virus Infection: The CHIMERE Cohort Study on Reunion Island

(2014) Patrick Gérardin et al.   PLoS Neglected Tropical Diseases

Endoplasmic Reticulum Chaperones and Oxidoreductases: Critical Regulators of Tumor Cell Survival and Immunorecognition

(2014) Tomás Gutiérrez et al.   Frontiers in Oncology

Phenotype, donor age and gender affect function of human bone marrow-derived mesenchymal stromal cells

(2013) Georg Siegel et al.   BMC Medicine

Neurocognitive disturbances associated with acute infectious mononucleosis, Ross River fever and Q fever: A preliminary investigation of inflammatory and genetic correlates

(2013) Erin Cvejic et al.   BRAIN BEHAVIOR AND IMMUNITY

Dysfunctional Brain-bone Marrow Communication: A Paradigm Shift in the Pathophysiology of Hypertension

(2013) Monica M. Santisteban et al.   CURRENT HYPERTENSION REPORTS

Dual Inhibitors of Monoamine Oxidase and Cholinesterase for the Treatment of Alzheimer Disease

(2013) Matilde Yanez et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Altered Inflammatory Response Is Associated With an Impaired Autonomic Input to the Bone Marrow in the Spontaneously Hypertensive Rat

(2013) Jasenka Zubcevic et al.   HYPERTENSION

Acetylcholinesterase Activity and Neurodevelopment in Boys and Girls

(2013) J. R. Suarez-Lopez et al.   PEDIATRICS

Alphaviruses: Population genetics and determinants of emergence

(2012) Scott C. Weaver et al.   ANTIVIRAL RESEARCH

A possible pathophysiological role of tyrosine hydroxylase in Parkinson’s disease suggested by postmortem brain biochemistry: a contribution for the special 70th birthday symposium in honor of Prof. Peter Riederer

(2012) Akira Nakashima et al.   JOURNAL OF NEURAL TRANSMISSION

Attenuation of Chikungunya Virus Vaccine Strain 181/Clone 25 Is Determined by Two Amino Acid Substitutions in the E2 Envelope Glycoprotein

(2012) R. Gorchakov et al.   JOURNAL OF VIROLOGY

Genetic associations of fatigue and other symptom domains of the acute sickness response to infection

(2011) B. Piraino et al.   BRAIN BEHAVIOR AND IMMUNITY

Hepatitis C Virus Proteins Inhibit C3 Complement Production

(2011) B. Mazumdar et al.   JOURNAL OF VIROLOGY

Neurodegeneration and Inflammation in Parkinson's disease

(2011) Sudarshan Phani et al.   PARKINSONISM & RELATED DISORDERS

Complement-Mediated Neutralization of Dengue Virus Requires Mannose-Binding Lectin

(2011) P. Avirutnan et al.   mBio

Direct Complement Restriction of Flavivirus Infection Requires Glycan Recognition by Mannose-Binding Lectin

(2010) Anja Fuchs et al.   Cell Host & Microbe

Persistent Chronic Inflammation and Infection by Chikungunya Arthritogenic Alphavirus in Spite of a Robust Host Immune Response

(2010) J. J. Hoarau et al.   JOURNAL OF IMMUNOLOGY

The Senescence-Related Mitochondrial/Oxidative Stress Pathway is Repressed in Human Induced Pluripotent Stem Cells

(2010) Alessandro Prigione et al.   STEM CELLS

Astrocytes: biology and pathology

(2009) Michael V. Sofroniew et al.   ACTA NEUROPATHOLOGICA

Changing patterns of West Nile virus transmission: altered vector competence and host susceptibility

(2009) Aaron C. Brault   VETERINARY RESEARCH

Viral parkinsonism

(2008) Haeman Jang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Cytokine Polymorphisms Have a Synergistic Effect on Severity of the Acute Sickness Response to Infection

(2008) Uté Vollmer‐Conna et al.   CLINICAL INFECTIOUS DISEASES