Fisetin Protects HaCaT Human Keratinocytes from Fine Particulate Matter (PM2.5)-Induced Oxidative Stress and Apoptosis by Inhibiting the Endoplasmic Reticulum Stress Response

Particulate matter (PM)2.5 affects keratinocytes via endoplasmic reticulum (ER) stress-mediated suppression of apoptosis

(2020) J. H. Kim et al.   Molecular & Cellular Toxicology

Fisetin induces autophagy in pancreatic cancer cells via endoplasmic reticulum stress- and mitochondrial stress-dependent pathways

(2019) Shengnan Jia et al.   Cell Death & Disease

Particulate matter-induced senescence of skin keratinocytes involves oxidative stress-dependent epigenetic modifications

(2019) Yea Seong Ryu et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Fisetin, a 3,7,3′,4′-Tetrahydroxyflavone Inhibits the PI3K/Akt/mTOR and MAPK Pathways and Ameliorates Psoriasis Pathology in 2D and 3D Organotypic Human Inflammatory Skin Models

(2019) Jean Christopher Chamcheu et al.   Cells

PM2.5, Fine Particulate Matter: A Novel Player in the Epithelial-Mesenchymal Transition?

(2019) Zihan Xu et al.   Frontiers in Physiology

Can Plant Phenolic Compounds Protect the Skin from Airborne Particulate Matter?

(2019) Yong Chool Boo   Antioxidants

Particulate matter 2.5 damages skin cells by inducing oxidative stress, subcellular organelle dysfunction, and apoptosis

(2018) Mei Jing Piao et al.   ARCHIVES OF TOXICOLOGY

Biological effects of airborne fine particulate matter (PM 2.5 ) exposure on pulmonary immune system

(2018) Tingting Wei et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

In Vitro and In Vivo Experimental Studies of PM2.5 on Disease Progression

(2018) Ching-Chang Cho et al.   International Journal of Environmental Research and Public Health

Fisetin Regulates Nrf2 Expression and the Inflammation-Related Signaling Pathway to Prevent UVB-Induced Skin Damage in Hairless Mice

(2017) Po-Yuan Wu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Inhibition of the sarco/endoplasmic reticulum (ER) Ca2+-ATPase by thapsigargin analogs induces cell death via ER Ca2+depletion and the unfolded protein response

(2017) Pankaj Sehgal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antioxidant properties of the flavonoid fisetin: An updated review of in vivo and in vitro studies

(2017) Alireza Farsad Naeimi et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Effects of Ambient Fine Particles PM2.5 on Human HaCaT Cells

(2017) Qiao Li et al.   International Journal of Environmental Research and Public Health

SHP-2 phosphatase controls aryl hydrocarbon receptor-mediated ER stress response in mast cells

(2016) Hsueh-Chun Wang et al.   ARCHIVES OF TOXICOLOGY

Activation of apoptosis signalling pathways by reactive oxygen species

(2016) Maureen Redza-Dutordoir et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The integrated stress response

(2016) Karolina Pakos‐Zebrucka et al.   EMBO REPORTS

Fisetin induces apoptosis and endoplasmic reticulum stress in human non-small cell lung cancer through inhibition of the MAPK signaling pathway

(2016) Kyoung Ah Kang et al.   TUMOR BIOLOGY

Fisetin Suppresses Macrophage-Mediated Inflammatory Responses by Blockade of Src and Syk

(2015) Jun Ho Kim et al.   Biomolecules & Therapeutics

Nanoscale characterization of PM2.5 airborne pollutants reveals high adhesiveness and aggregation capability of soot particles

(2015) Yuanyuan Shi et al.   Scientific Reports

Oxidative stress mediated Ca2+ release manifests endoplasmic reticulum stress leading to unfolded protein response in UV-B irradiated human skin cells

(2014) Mufti R. Farrukh et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Inhibition of eIF2α dephosphorylation enhances TRAIL-induced apoptosis in hepatoma cells

(2014) Y Teng et al.   Cell Death & Disease

The endoplasmic reticulum stress inhibitor salubrinal inhibits the activation of autophagy and neuroprotection induced by brain ischemic preconditioning

(2013) Bo Gao et al.   ACTA PHARMACOLOGICA SINICA

PM 2.5

(2013) J. Marshall   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fisetin: A Dietary Antioxidant for Health Promotion

(2012) Naghma Khan et al.   ANTIOXIDANTS & REDOX SIGNALING

Endoplasmic Reticulum Stress in Disease Pathogenesis

(2008) Jonathan H. Lin et al.   Annual Review of Pathology-Mechanisms of Disease