‘Carbon-Monoxide-Releasing Molecule-2 (CORM-2)’ Is a Misnomer: Ruthenium Toxicity, Not CO Release, Accounts for Its Antimicrobial Effects

Chemical Reactivities of Two Widely Used Ruthenium-Based CO-Releasing Molecules with a Range of Biologically Important Reagents and Molecules

(2021) Zhengnan Yuan et al.   ANALYTICAL CHEMISTRY

Ruthenium, Not Carbon Monoxide, Inhibits the Procoagulant Activity of Atheris, Echis, and Pseudonaja Venoms

(2020) Vance G. Nielsen   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Effects of frequently applied carbon monoxide releasing molecules (CORMs) in typical CO-sensitive model systems – A comparative in vitro study

(2020) David Stucki et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

DNA damage and antioxidant properties of CORM-2 in normal and cancer cells

(2020) Michał Juszczak et al.   Scientific Reports

CORM-2-entrapped ultradeformable liposomes ameliorate acute skin inflammation in an ear edema model via effective CO delivery

(2020) Gwan-Yeong Lee et al.   Acta Pharmaceutica Sinica B

Time-dependent course of gastric ulcer healing and molecular markers profile modulated by increased gastric mucosal content of carbon monoxide released from its pharmacological donor

(2019) Katarzyna Magierowska et al.   BIOCHEMICAL PHARMACOLOGY

Metabolomics of Escherichia coli treated with the antimicrobial Carbon Monoxide-Releasing Molecule CORM-3 reveals TCA cycle as major target

(2019) Sandra M. Carvalho et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Recent Developments in the Design of Mn‐ and Ru‐based Hybrid CO‐Releasing Molecules (HYCOs)

(2019) Anthony Ollivier et al.   ChemMedChem

The anticoagulant effect of Apis mellifera phospholipase A2 is inhibited by CORM-2 via a carbon monoxide-independent mechanism

(2019) Vance G. Nielsen   JOURNAL OF THROMBOSIS AND THROMBOLYSIS

Carbon Monoxide-Releasing Molecule Enhances Coagulation and Decreases Fibrinolysis in Normal Canine Plasma

(2018) Dillon Donaghy et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Intermittent, low dose carbon monoxide exposure enhances survival and dopaminergic differentiation of human neural stem cells

(2018) Nanna Dreyer-Andersen et al.   PLoS One

The Antimicrobial Activity of Mononuclear Ruthenium(II) Complexes Containing the dppz Ligand

(2018) Xuewen Liu et al.   ChemPlusChem

A thiol-reactive Ru(II) ion, not CO release, underlies the potent antimicrobial and cytotoxic properties of CO-releasing molecule-3

(2018) Hannah M. Southam et al.   Redox Biology

Aspects of Carbon Monoxide in Form of CO-Releasing Molecules Used in Cancer Treatment: More Light on the Way

(2017) Malamati Kourti et al.   Oxidative Medicine and Cellular Longevity

Gaseous Mediators and Mitochondrial Function: The Future of Pharmacologically Induced Suspended Animation?

(2017) Clair Hartmann et al.   Frontiers in Physiology

Carbon Monoxide Gas Is Not Inert, but Global, in Its Consequences for Bacterial Gene Expression, Iron Acquisition, and Antibiotic Resistance

(2016) Lauren K. Wareham et al.   ANTIOXIDANTS & REDOX SIGNALING

Examining the antimicrobial activity and toxicity to animal cells of different types of CO-releasing molecules

(2016) Lígia S. Nobre et al.   DALTON TRANSACTIONS

Five-coordinate H64Q neuroglobin as a ligand-trap antidote for carbon monoxide poisoning

(2016) I. Azarov et al.   Science Translational Medicine

A contribution to the rational design of Ru(CO)3Cl2L complexes for in vivo delivery of CO

(2015) João D. Seixas et al.   DALTON TRANSACTIONS

Heme as a danger molecule in pathogen recognition

(2015) Barbara Wegiel et al.   FREE RADICAL BIOLOGY AND MEDICINE

CO-releasing Metal Carbonyl Compounds as Antimicrobial Agents in the Post-antibiotic Era

(2015) Lauren K. Wareham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Carbon monoxide and the CNS: challenges and achievements

(2014) Cláudia S F Queiroga et al.   BRITISH JOURNAL OF PHARMACOLOGY

Macrophages sense and kill bacteria through carbon monoxide–dependent inflammasome activation

(2014) Barbara Wegiel et al.   JOURNAL OF CLINICAL INVESTIGATION

Oral drug delivery of therapeutic gases — Carbon monoxide release for gastrointestinal diseases

(2014) Christoph Steiger et al.   JOURNAL OF CONTROLLED RELEASE

IR Spectroscopic Methods for the Investigation of the CO Release from CORMs

(2014) Moritz Klein et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Interaction of the carbon monoxide-releasing molecule Ru(CO)3Cl(glycinate) (CORM-3) with Salmonella enterica serovar Typhimurium: in situ measurements of carbon monoxide binding by integrating cavity dual-beam spectrophotometry

(2014) N. Rana et al.   MICROBIOLOGY-SGM

Antidote for carbon monoxide poisoning

(2014) Ivan Azarov et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Analysis of the Bacterial Response to Ru(CO)3Cl(Glycinate) (CORM-3) and the Inactivated Compound Identifies the Role Played by the Ruthenium Compound and Reveals Sulfur-Containing Species as a Major Target of CORM-3 Action

(2013) Samantha McLean et al.   ANTIOXIDANTS & REDOX SIGNALING

Cytochrome bd-I in Escherichia coli is less sensitive than cytochromes bd-II or bo′' to inhibition by the carbon monoxide-releasing molecule, CORM-3

(2013) Helen E. Jesse et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Carbon monoxide releasing molecule-2 attenuated ischemia/reperfusion-induced apoptosis in cardiomyocytes via a mitochondrial pathway

(2013) SHEN ZHAO et al.   Molecular Medicine Reports

Using chemical shift perturbation to characterise ligand binding

(2013) Mike P. Williamson   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

cor, a Novel Carbon Monoxide Resistance Gene, Is Essential for Mycobacterium tuberculosis Pathogenesis

(2013) V. M. Zacharia et al.   mBio

Carbon monoxide: present and future indications for a medical gas

(2013) Stefan W. Ryter et al.   KOREAN JOURNAL OF INTERNAL MEDICINE

Sulfite species enhance carbon monoxide release from CO-releasing molecules: Implications for the deoxymyoglobin assay of activity

(2012) Samantha McLean et al.   ANALYTICAL BIOCHEMISTRY

Ru(CO)3Cl(Glycinate) (CORM-3): A Carbon Monoxide–Releasing Molecule with Broad-Spectrum Antimicrobial and Photosensitive Activities Against Respiration and Cation Transport in Escherichia coli

(2012) Jayne Louise Wilson et al.   ANTIOXIDANTS & REDOX SIGNALING

Cell Damage Following Carbon Monoxide Releasing Molecule Exposure: Implications for Therapeutic Applications

(2012) Ian C. Winburn et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Developing drug molecules for therapy with carbon monoxide

(2012) Carlos C. Romão et al.   CHEMICAL SOCIETY REVIEWS

A role for reactive oxygen species in the antibacterial properties of carbon monoxide-releasing molecules

(2012) Ana Filipa N. Tavares et al.   FEMS MICROBIOLOGY LETTERS

CO-Releasing Molecules: A Personal View

(2012) Brian E. Mann   ORGANOMETALLICS

Differential Antibacterial Activity Against Pseudomonas aeruginosa by Carbon Monoxide-Releasing Molecules

(2011) Mathieu Desmard et al.   ANTIOXIDANTS & REDOX SIGNALING

A “Sliding Scale Rule” for Selectivity among NO, CO, and O2 by Heme Protein Sensors

(2011) Ah-Lim Tsai et al.   BIOCHEMISTRY

Reactive Oxygen Species Mediate Bactericidal Killing Elicited by Carbon Monoxide-releasing Molecules

(2011) Ana Filipa N. Tavares et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exploring the antimicrobial action of a carbon monoxide-releasing compound through whole-genome transcription profiling of Escherichia coli

(2009) L. S. Nobre et al.   MICROBIOLOGY-SGM

Tricarbonyldichlororuthenium (II) dimer (CORM2) activates non-selective cation current in human endothelial cells independently of carbon monoxide releasing

(2008) De-Li Dong et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Use of carbon monoxide as a therapeutic agent: promises and challenges

(2008) Roberta Foresti et al.   INTENSIVE CARE MEDICINE

Carbon Monoxide-releasing Antibacterial Molecules Target Respiration and Global Transcriptional Regulators

(2008) Kelly S. Davidge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heme oxygenase-1–derived carbon monoxide enhances the host defense response to microbial sepsis in mice

(2008) Su Wol Chung et al.   JOURNAL OF CLINICAL INVESTIGATION