Examining the antimicrobial activity and toxicity to animal cells of different types of CO-releasing molecules

A contribution to the rational design of Ru(CO)3Cl2L complexes for in vivo delivery of CO

(2015) João D. Seixas et al.   DALTON TRANSACTIONS

Antibacterial and Antiparasitic Activity of Manganese(I) Tricarbonyl Complexes with Ketoconazole, Miconazole, and Clotrimazole Ligands

(2015) Peter V. Simpson et al.   ORGANOMETALLICS

Exogenous carbon monoxide suppresses Escherichia coli vitality and improves survival in an Escherichia coli-induced murine sepsis model

(2014) Wei-chang Shen et al.   ACTA PHARMACOLOGICA SINICA

Spontaneous CO Release from RuII(CO)2-Protein Complexes in Aqueous Solution, Cells, and Mice

(2014) Miguel Chaves-Ferreira et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Carbon-Monoxide-Releasing Molecules for the Delivery of Therapeutic CO In Vivo

(2014) Sandra García-Gallego et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Syntheses, toxicity and biodistribution of CO-releasing molecules containing M(CO)5(M = Mo, W and Cr)

(2014) Huapeng Liu et al.   APPLIED ORGANOMETALLIC CHEMISTRY

Carbon monoxide – physiology, detection and controlled release

(2014) Stefan H. Heinemann et al.   CHEMICAL COMMUNICATIONS

Visible-Light-Induced CO Release from a Therapeutically Viable Tryptophan-Derived Manganese(I) Carbonyl (TryptoCORM) Exhibiting Potent Inhibition againstE. coli

(2014) Jonathan S. Ward et al.   CHEMISTRY-A EUROPEAN JOURNAL

New modular manganese(i) tricarbonyl complexes as PhotoCORMs: in vitro detection of photoinduced carbon monoxide release using COP-1 as a fluorogenic switch-on probe

(2014) Sandesh Pai et al.   DALTON TRANSACTIONS

Introducing [Mn(CO)3(tpa-κ3N)]+ as a novel photoactivatable CO-releasing molecule with well-defined iCORM intermediates – synthesis, spectroscopy, and antibacterial activity

(2014) Christoph Nagel et al.   DALTON TRANSACTIONS

Carbon Monoxide-releasing Molecule-3 (CORM-3; Ru(CO)3Cl(Glycinate)) as a Tool to Study the Concerted Effects of Carbon Monoxide and Nitric Oxide on Bacterial Flavohemoglobin Hmp

(2014) Mariana Tinajero-Trejo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CO and CO-releasing molecules in medicinal chemistry

(2013) Fabio Zobi   Future Medicinal Chemistry

Carbon Monoxide Abrogates Ischemic Insult to Neuronal Cells via the Soluble Guanylate Cyclase-cGMP Pathway

(2013) Nils Schallner et al.   PLoS One

The Bactericidal Activity of Carbon Monoxide–Releasing Molecules against Helicobacter pylori

(2013) Ana F. Tavares et al.   PLoS One

Sulfite species enhance carbon monoxide release from CO-releasing molecules: Implications for the deoxymyoglobin assay of activity

(2012) Samantha McLean et al.   ANALYTICAL BIOCHEMISTRY

Ru(CO)3Cl(Glycinate) (CORM-3): A Carbon Monoxide–Releasing Molecule with Broad-Spectrum Antimicrobial and Photosensitive Activities Against Respiration and Cation Transport in Escherichia coli

(2012) Jayne Louise Wilson et al.   ANTIOXIDANTS & REDOX SIGNALING

Developing drug molecules for therapy with carbon monoxide

(2012) Carlos C. Romão et al.   CHEMICAL SOCIETY REVIEWS

Characterization of a versatile organometallic pro-drug (CORM) for experimental CO based therapeutics

(2012) João D. Seixas et al.   DALTON TRANSACTIONS

Carbon Monoxide and Heme Oxygenase-1 Prevent Intestinal Inflammation in Mice by Promoting Bacterial Clearance

(2012) Joseph C. Onyiah et al.   GASTROENTEROLOGY

Reactivity Studies of Oxo–Mo(IV) Complexes Containing Potential Hydrogen-Bond Acceptor/Donor Phenolate Ligands

(2012) Victor Wee Lin Ng et al.   INORGANIC CHEMISTRY

New insights into the chemistry of fac-[Ru(CO)3]2+ fragments in biologically relevant conditions: The CO releasing activity of [Ru(CO)3Cl2(1,3-thiazole)], and the X-ray crystal structure of its adduct with lysozyme

(2012) M.F.A. Santos et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

A Reaction-Based Fluorescent Probe for Selective Imaging of Carbon Monoxide in Living Cells Using a Palladium-Mediated Carbonylation

(2012) Brian W. Michel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

CO-Releasing Molecules: A Personal View

(2012) Brian E. Mann   ORGANOMETALLICS

Differential Antibacterial Activity Against Pseudomonas aeruginosa by Carbon Monoxide-Releasing Molecules

(2011) Mathieu Desmard et al.   ANTIOXIDANTS & REDOX SIGNALING

Designed Iron Carbonyls as Carbon Monoxide (CO) Releasing Molecules: Rapid CO Release and Delivery to Myoglobin in Aqueous Buffer, and Vasorelaxation of Mouse Aorta

(2011) Margarita A. Gonzalez et al.   INORGANIC CHEMISTRY

The carbon monoxide-releasing molecule, corm-3 (ru(co)3cl(glycinate)), targets respiration and oxidases in campylobacter jejuni, generating hydrogen peroxide

(2011) Holly Smith et al.   IUBMB LIFE

Reactive Oxygen Species Mediate Bactericidal Killing Elicited by Carbon Monoxide-releasing Molecules

(2011) Ana Filipa N. Tavares et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Anti-Inflammatory Role for Carbon Monoxide and Heme Oxygenase-1 in Chronic Th2-Mediated Murine Colitis

(2011) S. Z. Sheikh et al.   JOURNAL OF IMMUNOLOGY

CORM-3 Reactivity toward Proteins: The Crystal Structure of a Ru(II) Dicarbonyl−Lysozyme Complex

(2011) Teresa Santos-Silva et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

fac-{Ru(CO)3}2+Selectively Targets the Histidine Residues of the β-Amyloid Peptide 1-28. Implications for New Alzheimer's Disease Treatments Based on Ruthenium Complexes

(2010) Daniela Valensin et al.   INORGANIC CHEMISTRY

The therapeutic potential of carbon monoxide

(2010) Roberto Motterlini et al.   NATURE REVIEWS DRUG DISCOVERY

Diversity and design of metal-based carbon monoxide-releasing molecules (CO-RMs) in aqueous systems: revealing the essential trends

(2009) Wei-Qiang Zhang et al.   DALTON TRANSACTIONS

Therapeutic applications of the gaseous mediators carbon monoxide and hydrogen sulfide

(2009) Gerard L Bannenberg et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Exploring the antimicrobial action of a carbon monoxide-releasing compound through whole-genome transcription profiling of Escherichia coli

(2009) L. S. Nobre et al.   MICROBIOLOGY-SGM

A carbon monoxide-releasing molecule (CORM-3) exerts bactericidal activity against Pseudomonas aeruginosa and improves survival in an animal model of bacteraemia

(2008) Mathieu Desmard et al.   FASEB JOURNAL

Carbon Monoxide-releasing Antibacterial Molecules Target Respiration and Global Transcriptional Regulators

(2008) Kelly S. Davidge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY