Omics Technologies to Decipher Regulatory Networks in Granulocytic Cell Differentiation

Acute promyelocytic leukemia (APL): a review of the literature

(2020) Joaquin J. Jimenez et al.   Oncotarget

Functional Classification of TP53 Mutations in Acute Myeloid Leukemia

(2020) Sayantanee Dutta et al.   Cancers

VolcaNoseR is a web app for creating, exploring, labeling and sharing volcano plots

(2020) Joachim Goedhart et al.   Scientific Reports

PARP inhibitors in breast cancer: Bringing synthetic lethality to the bedside

(2018) Anita A. Turk et al.   CANCER

Dual Mechanisms of LYN Kinase Dysregulation Drive Aggressive Behavior in Breast Cancer Cells

(2018) Giusy Tornillo et al.   Cell Reports

An Effective Model of the Retinoic Acid Induced HL-60 Differentiation Program

(2017) Ryan Tasseff et al.   Scientific Reports

Lyn, a tyrosine kinase closely linked to the differentiation status of primary acute myeloid leukemia blasts, associates with negative regulation of all-trans retinoic acid (ATRA) and dihydroxyvitamin D3 (VD3)-induced HL-60 cells differentiation

(2016) Noriyoshi Iriyama et al.   Cancer Cell International

p53 in the DNA-Damage-Repair Process

(2016) Ashley B. Williams et al.   Cold Spring Harbor Perspectives in Medicine

BRCA1, PARP1 and γH2AX in acute myeloid leukemia: Role as biomarkers of response to the PARP inhibitor olaparib

(2015) Isabella Faraoni et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

An ATRActive future for differentiation therapy in AML

(2015) Daniel E. Johnson et al.   BLOOD REVIEWS

Acute promyelocytic leukemia: where did we start, where are we now and the future

(2015) C C Coombs et al.   Blood Cancer Journal

Distinguishing between cancer cell differentiation and resistance induced by all-trans retinoic acid using transcriptional profiles and functional pathway analysis

(2014) Song-Mei Liu et al.   Scientific Reports

Crosstalk between poly(ADP-ribose) polymerase and sirtuin enzymes

(2013) Carles Cantó et al.   MOLECULAR ASPECTS OF MEDICINE

Chromosome 18 Transcriptome Profiling and Targeted Proteome Mapping in Depleted Plasma, Liver Tissue and HepG2 Cells

(2012) Victor G. Zgoda et al.   JOURNAL OF PROTEOME RESEARCH

Poly(ADP-ribosyl)ation of p53 induces gene-specific transcriptional repression of MTA1

(2012) M-H Lee et al.   ONCOGENE

A Positive Feedback Signaling Loop between ATM and the Vitamin D Receptor Is Critical for Cancer Chemoprevention by Vitamin D

(2011) H.-J. Ting et al.   CANCER RESEARCH

SPIRE: Systematic protein investigative research environment

(2011) Eugene Kolker et al.   Journal of Proteomics

Autophagy contributes to therapy-induced degradation of the PML/RARA oncoprotein

(2010) P. Isakson et al.   BLOOD

Proteomic cell surface phenotyping of differentiating acute myeloid leukemia cells

(2010) A. Hofmann et al.   BLOOD

ATRA-induced HL-60 myeloid leukemia cell differentiation depends on the CD38 cytosolic tail needed for membrane localization, but CD38 enzymatic activity is unnecessary

(2010) Johanna Congleton et al.   EXPERIMENTAL CELL RESEARCH

Aberrant Corepressor Interactions Implicated in PML-RARα and PLZF-RARα Leukemogenesis Reflect an Altered Recruitment and Release of Specific NCoR and SMRT Splice Variants

(2010) Brenda J. Mengeling et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Analysis of Lyn Kinase A and B Isoforms Reveals Redundant and Distinct Roles in Fc RI-Dependent Mast Cell Activation

(2010) D. Alvarez-Errico et al.   JOURNAL OF IMMUNOLOGY

Gene expression analysis of human promyelocytic leukemia HL-60 cell differentiation and cytotoxicity induced by natural and synthetic retinoids

(2009) Jin Wang et al.   LIFE SCIENCES

Differential gene expression patterns coupled to commitment and acquisition of phenotypic hallmarks during neutrophil differentiation of human leukaemia HL-60 cells

(2008) Faustino Mollinedo et al.   GENE

Apoptotic signaling by c-MYC

(2008) B Hoffman et al.   ONCOGENE

ExPlain™: finding upstream drug targets in disease gene regulatory networks

(2008) A. Kel et al.   SAR AND QSAR IN ENVIRONMENTAL RESEARCH