Lyn, a tyrosine kinase closely linked to the differentiation status of primary acute myeloid leukemia blasts, associates with negative regulation of all-trans retinoic acid (ATRA) and dihydroxyvitamin D3 (VD3)-induced HL-60 cells differentiation

Dasatinib enhances cisplatin sensitivity in human esophageal squamous cell carcinoma (ESCC) cells via suppression of PI3K/AKT and Stat3 pathways

(2015) Jie Chen et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

ETV6/ARG oncoprotein confers autonomous cell growth by enhancing c-Myc expression via signal transducer and activator of transcription 5 activation in the acute promyelocytic leukemia cell line HT93A

(2014) Noriyoshi Iriyama et al.   LEUKEMIA & LYMPHOMA

The Src and c-Kit kinase inhibitor dasatinib enhances p53-mediated targeting of human acute myeloid leukemia stem cells by chemotherapeutic agents

(2013) C. Dos Santos et al.   BLOOD

TIS21/BTG2/PC3 enhances downregulation of c-Myc during differentiation of HL-60 cells by activating Erk1/2 and inhibiting Akt in response to all-trans-retinoic acid

(2012) Muhammad Imran et al.   EUROPEAN JOURNAL OF CANCER

Src inhibitors, PP2 and dasatinib, increase retinoic acid-induced association of Lyn and c-Raf (S259) and enhance MAPK-dependent differentiation of myeloid leukemia cells

(2011) J Congleton et al.   LEUKEMIA

The potential for dasatinib in treating chronic lymphocytic leukemia, acute myeloid leukemia, and myeloproliferative neoplasms

(2011) Philip C. Amrein   LEUKEMIA & LYMPHOMA

Randomized study of induction therapy comparing standard-dose idarubicin with high-dose daunorubicin in adult patients with previously untreated acute myeloid leukemia: the JALSG AML201 Study

(2010) S. Ohtake et al.   BLOOD

A randomized comparison of 4 courses of standard-dose multiagent chemotherapy versus 3 courses of high-dose cytarabine alone in postremission therapy for acute myeloid leukemia in adults: the JALSG AML201 Study

(2010) S. Miyawaki et al.   BLOOD

Dasatinib Inhibits the Growth of Molecularly Heterogeneous Myeloid Leukemias

(2010) B. S. Guerrouahen et al.   CLINICAL CANCER RESEARCH

Advances in Targeting Src in the Treatment of Breast Cancer and Other Solid Malignancies

(2010) E. L. Mayer et al.   CLINICAL CANCER RESEARCH

Dasatinib induces long-term remission in imatinib-resistant Philadelphia chromosome-positive acute megakaryoblastic leukemia but fails to prevent development of central nervous system progression

(2010) Sotirios G. Papageorgiou et al.   LEUKEMIA RESEARCH

Dasatinib promotes ATRA-induced differentiation of AML cells

(2009) P L Kropf et al.   LEUKEMIA

Association Between Imatinib-Resistant BCR-ABL Mutation-Negative Leukemia and Persistent Activation of LYN Kinase

(2008) Ji Wu et al.   JNCI-Journal of the National Cancer Institute

Role of Myc in differentiation and apoptosis in HL60 cells after exposure to arsenic trioxide or all-trans retinoic acid

(2007) Guosheng Jiang et al.   LEUKEMIA RESEARCH