Extracellular Vesicles Derived From Human Umbilical Cord Mesenchymal Stem Cells Protect Against DOX-Induced Heart Failure Through the miR-100-5p/NOX4 Pathway

The Role of Exosomes and Exosomal MicroRNA in Cardiovascular Disease

(2021) Dongdong Zheng et al.   Frontiers in Cell and Developmental Biology

Effects of Lycium barbarum L. Polysaccharides on Inflammation and Oxidative Stress Markers in a Pressure Overload-Induced Heart Failure Rat Model

(2020) Cristina Pop et al.   MOLECULES

Heart Failure and Adipose Mesenchymal Stem Cells

(2020) Kenichi Matsushita   TRENDS IN MOLECULAR MEDICINE

Mesenchymal stem cell therapy for patients with ischemic heart failure —past, present, and future

(2020) Fang Chen et al.   Current Stem Cell Research & Therapy

Cardiotoxicity and Heart Failure: Lessons from Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes and Anticancer Drugs

(2020) Agapios Sachinidis   Cells

Novel Applications of Mesenchymal Stem Cell-Derived Exosomes for Myocardial Infarction Therapeutics

(2020) Sho Joseph Ozaki Tan et al.   Biomolecules

NRF2 is a key regulator of endothelial microRNA expression under proatherogenic stimuli

(2020) Suvi Linna-Kuosmanen et al.   CARDIOVASCULAR RESEARCH

Bone marrow mesenchymal stem cell-derived exosomes attenuate cardiac hypertrophy and fibrosis in pressure overload induced remodeling

(2020) Fu Chen et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Adiponectin Stimulates Exosome Release to Enhance Mesenchymal Stem-Cell-Driven Therapy of Heart Failure in Mice

(2020) Yuto Nakamura et al.   MOLECULAR THERAPY

Exosomes - Beyond Stem Cells for Cardiac Protection and Repair

(2020) Carolina Balbi et al.   STEM CELLS

CAR (CARSKNKDC) Peptide Modified ReNcell-Derived Extracellular Vesicles as a Novel Therapeutic Agent for Targeted Pulmonary Hypertension Therapy

(2020) Jie Wang et al.   HYPERTENSION

Echinacoside reverses myocardial remodeling and improves heart function via regulating SIRT1/FOXO3a/MnSOD axis in HF rats induced by isoproterenol

(2020) Yajuan Ni et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

What is the impact of human umbilical cord mesenchymal stem cell transplantation on clinical treatment?

(2020) Qixin Xie et al.   Stem Cell Research & Therapy

Longterm Exercise-Derived Exosomal miR-342-5p: A Novel Exerkine for Cardioprotection

(2019) Zuoxu Hou et al.   CIRCULATION RESEARCH

Pharmacological strategies to lower crosstalk between nicotinamide adenine dinucleotide phosphate (NADPH) oxidase and mitochondria

(2019) Nirmala Koju et al.   BIOMEDICINE & PHARMACOTHERAPY

Comparison of biological characteristics of mesenchymal stem cells derived from the human umbilical cord and decidua parietalis

(2019) Yu‑Tao Guan et al.   Molecular Medicine Reports

Exosomes Derived from TIMP2-Modified Human Umbilical Cord Mesenchymal Stem Cells Enhance the Repair Effect in Rat Model with Myocardial Infarction Possibly by the Akt/Sfrp2 Pathway

(2019) Jing Ni et al.   Oxidative Medicine and Cellular Longevity

Diagnostic and Theranostic microRNAs in the Pathogenesis of Atherosclerosis

(2019) Sara Shoeibi   Acta Physiologica

Role of TLR4/NADPH oxidase 4 pathway in promoting cell death through autophagy and ferroptosis during heart failure

(2019) Xiaoqing Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The NADPH oxidase inhibitor apocynin improves cardiac sympathetic nerve terminal innervation and function in heart failure

(2019) Ke Wang et al.   EXPERIMENTAL PHYSIOLOGY

Isolevuglandin scavenger attenuates pressure overload-induced cardiac oxidative stress, cardiac hypertrophy, heart failure and lung remodeling

(2019) Linlin Shang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Role of oxidative stress-related biomarkers in heart failure: galectin 3, α1-antitrypsin and LOX-1: new therapeutic perspective?

(2019) Valter Lubrano et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

LongShengZhi capsule inhibits doxorubicin-induced heart failure by anti-oxidative stress

(2019) Shuai Xu et al.   BIOMEDICINE & PHARMACOTHERAPY

Exosomes and cardioprotection – A critical analysis

(2018) Sean M. Davidson et al.   MOLECULAR ASPECTS OF MEDICINE

Mesenchymal Stem/Stromal Cell-Based Therapy for Heart Failure　― What Is the Best Source? ―

(2018) Kazuya Kobayashi et al.   CIRCULATION JOURNAL

Mitochondrial dysfunction in pathophysiology of heart failure

(2018) Bo Zhou et al.   JOURNAL OF CLINICAL INVESTIGATION

Comparison of the biological characteristics of human mesenchymal stem cells derived from exfoliated deciduous teeth, bone marrow, gingival tissue, and umbilical cord

(2018) Jing Li et al.   Molecular Medicine Reports

The Genetic Determination of the Differentiation Between Ischemic Dilated Cardiomyopathy and Idiopathic Dilated Cardiomyopathy

(2018) Serap Tutgun Onrat et al.   Genetic Testing and Molecular Biomarkers

Intramuscular injection of human umbilical cord-derived mesenchymal stem cells improves cardiac function in dilated cardiomyopathy rats

(2017) Chenggang Mao et al.   Stem Cell Research & Therapy

MicroRNA-100 Suppresses Chronic Vascular Inflammation by Stimulation of Endothelial Autophagy

(2017) Franziska Pankratz et al.   CIRCULATION RESEARCH

Long-term Intake of Pasta Containing Barley (1–3)Beta-D-Glucan Increases Neovascularization-mediated Cardioprotection through Endothelial Upregulation of Vascular Endothelial Growth Factor and Parkin

(2017) Valentina Casieri et al.   Scientific Reports

Communication by Extracellular Vesicles: Where We Are and Where We Need to Go

(2016) Mercedes Tkach et al.   CELL

Cardiopoietic cell therapy for advanced ischemic heart failure: results at 39 weeks of the prospective, randomized, double blind, sham-controlled CHART-1 clinical trial

(2016) Jozef Bartunek et al.   EUROPEAN HEART JOURNAL

Intramyocardial transplantation of mesenchymal stromal cells for chronic myocardial ischemia and impaired left ventricular function: Results of the MESAMI 1 pilot trial

(2016) D. Guijarro et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

ExoCarta: A Web-Based Compendium of Exosomal Cargo

(2016) Shivakumar Keerthikumar et al.   JOURNAL OF MOLECULAR BIOLOGY

Silencing of USP22 suppresses high glucose-induced apoptosis, ROS production and inflammation in podocytes

(2016) Jian-xia Shi et al.   Molecular BioSystems

Gestational hypertension, preeclampsia and intrauterine growth restriction induce dysregulation of cardiovascular and cerebrovascular disease associated microRNAs in maternal whole peripheral blood

(2016) Ilona Hromadnikova et al.   THROMBOSIS RESEARCH

Functional characterization of human umbilical cord-derived mesenchymal stem cells for treatment of systolic heart failure

(2016) Zhihua Fang et al.   Experimental and Therapeutic Medicine

Endogenous MicroRNAs in Human Microvascular Endothelial Cells Regulate mRNAs Encoded by Hypertension-Related GenesNovelty and Significance

(2015) Alison J. Kriegel et al.   HYPERTENSION

The human Nox4: gene, structure, physiological function and pathological significance

(2015) Shuhui Guo et al.   JOURNAL OF DRUG TARGETING

NADPH oxidases: an overview from structure to innate immunity-associated pathologies

(2014) Arvind Panday et al.   Cellular & Molecular Immunology

Bone marrow-derived mesenchymal stem cells for the treatment of heart failure

(2014) Takuya Narita et al.   HEART FAILURE REVIEWS

Barley beta-glucan promotes MnSOD expression and enhances angiogenesis under oxidative microenvironment

(2014) Silvia Agostini et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Cardioprotective effects of fish omega-3 fatty acids on doxorubicin-induced cardiotoxicity in rats

(2013) R Uygur et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

The protective effects of ω-3 fatty acids on doxorubicin-induced hepatotoxicity and nephrotoxicity in rats

(2013) Feti Tulubas et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Exosomes: Current knowledge of their composition, biological functions, and diagnostic and therapeutic potentials

(2012) Alexander V. Vlassov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Nox4 Is a Protective Reactive Oxygen Species Generating Vascular NADPH Oxidase

(2012) Katrin Schröder et al.   CIRCULATION RESEARCH

Endothelial Nox4 NADPH Oxidase Enhances Vasodilatation and Reduces Blood Pressure In Vivo

(2011) Robin Ray et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes

(2011) A. Montecalvo et al.   BLOOD

MicroRNA-100 Regulates Neovascularization by Suppression of Mammalian Target of Rapamycin in Endothelial and Vascular Smooth Muscle Cells

(2011) Sebastian Grundmann et al.   CIRCULATION

Nox4 regulates Nrf2 and glutathione redox in cardiomyocytes in vivo

(2011) Alison C. Brewer et al.   FREE RADICAL BIOLOGY AND MEDICINE

NADPH oxidases in cardiovascular disease

(2010) Ralf P. Brandes et al.   FREE RADICAL BIOLOGY AND MEDICINE

NADPH oxidase-4 mediates protection against chronic load-induced stress in mouse hearts by enhancing angiogenesis

(2010) M. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nrf2 Protects Against Maladaptive Cardiac Responses to Hemodynamic Stress

(2009) Jinqing Li et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY