ORF3a-Mediated Incomplete Autophagy Facilitates Severe Acute Respiratory Syndrome Coronavirus-2 Replication

The interplay between emerging human coronavirus infections and autophagy

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A genome-wide CRISPR screen identifies host factors that regulate SARS-CoV-2 entry

(2021) Yunkai Zhu et al.   Nature Communications

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV

(2021) Alexey Stukalov et al.   NATURE

The SARS-CoV-2 protein ORF3a inhibits fusion of autophagosomes with lysosomes

(2021) Yabin Zhang et al.   Cell Discovery

Chloroquine and hydroxychloroquine as available weapons to fight COVID-19

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Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

A new coronavirus associated with human respiratory disease in China

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A pneumonia outbreak associated with a new coronavirus of probable bat origin

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Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

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SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

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New insights on the antiviral effects of chloroquine against coronavirus: what to expect for COVID-19?

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Viral and host factors related to the clinical outcome of COVID-19

(2020) Xiaonan Zhang et al.   NATURE

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

(2020) David E. Gordon et al.   NATURE

Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies

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Open questions for harnessing autophagy-modulating drugs in the SARS-CoV-2 war: hope or hype?

(2020) Patrick Brest et al.   Autophagy

Autophagy/virophagy: a “disposal strategy” to combat COVID-19

(2020) Dalibor Mijaljica et al.   Autophagy

Chloroquine does not inhibit infection of human lung cells with SARS-CoV-2

(2020) Markus Hoffmann et al.   NATURE

Hydroxychloroquine use against SARS-CoV-2 infection in non-human primates

(2020) Pauline Maisonnasse et al.   NATURE

Immune-mediated approaches against COVID-19

(2020) Helena F. Florindo et al.   Nature Nanotechnology

Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients

(2020) Jérôme Hadjadj et al.   SCIENCE

A molecular pore spans the double membrane of the coronavirus replication organelle

(2020) Georg Wolff et al.   SCIENCE

Coronavirus interactions with the cellular autophagy machinery

(2020) Katelyn Miller et al.   Autophagy

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms

(2020) David E. Gordon et al.   SCIENCE

Genetic Screens Identify Host Factors for SARS-CoV-2 and Common Cold Coronaviruses

(2020) Ruofan Wang et al.   CELL

ORF3a of the COVID-19 virus SARS-CoV-2 blocks HOPS complex-mediated assembly of the SNARE complex required for autolysosome formation

(2020) Guangyan Miao et al.   DEVELOPMENTAL CELL

Autophagy during viral infection — a double-edged sword

(2018) Younho Choi et al.   NATURE REVIEWS MICROBIOLOGY

Mechanism and medical implications of mammalian autophagy

(2018) Ivan Dikic et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Autophagosome maturation: An epic journey from the ER to lysosomes

(2018) Yan G. Zhao et al.   JOURNAL OF CELL BIOLOGY

A novel role of vBcl2 in the virion assembly of Kaposi's sarcoma-associated herpesvirus

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Zika Virus NS4A and NS4B Proteins Deregulate Akt-mTOR Signaling in Human Fetal Neural Stem Cells to Inhibit Neurogenesis and Induce Autophagy

(2016) Qiming Liang et al.   Cell Stem Cell

KSHV strategies for host dsDNA sensing machinery

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Beclin orthologs: integrative hubs of cell signaling, membrane trafficking, and physiology

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Downregulation of autophagy by herpesvirus Bcl-2 homologs

(2014) Chengyu Liang et al.   Autophagy

Coronavirus NSP6 restricts autophagosome expansion

(2014) Eleanor M Cottam et al.   Autophagy

Crosstalk between the cGAS DNA Sensor and Beclin-1 Autophagy Protein Shapes Innate Antimicrobial Immune Responses

(2014) Qiming Liang et al.   Cell Host & Microbe

Autophagy and Viruses: Adversaries or Allies?

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Kaposi's Sarcoma-Associated Herpesvirus K7 Modulates Rubicon-Mediated Inhibition of Autophagosome Maturation

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FLIP-mediated autophagy regulation in cell death control

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Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1–phosphatidylinositol-3-kinase complex

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Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages

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Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking

(2008) Chengyu Liang et al.   NATURE CELL BIOLOGY