Fucoidan-Supplemented Diet Potentiates Immune Checkpoint Blockage by Enhancing Antitumor Immunity

A review of cancer immunotherapy toxicity

(2020) Lucy Boyce Kennedy et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Effects of fucoidan on gut flora and tumor prevention in 1,2-dimethylhydrazine-induced colorectal carcinogenesis

(2020) Meilan Xue et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The role of short-chain fatty acids in immunity, inflammation and metabolism

(2020) Yao Yao et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Ketogenic diet and ketone bodies enhance the anticancer effects of PD-1 blockade

(2020) Gladys Ferrere et al.   JCI Insight

Targeting gut microbiota with dietary components on cancer: Effects and potential mechanisms of action

(2019) Jun Tao et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Fucoidan (FUC) and galactooligosaccharides (GOS) ameliorate high-fat-diet-induced dyslipidemia in rats by modulating the gut microbiota and bile acid metabolism

(2019) Qichao Chen et al.   NUTRITION

Biological Activities of Fucoidan and the Factors Mediating Its Therapeutic Effects: A Review of Recent Studies

(2019) Yu Wang et al.   Marine Drugs

Nivolumab versus chemotherapy in patients with advanced oesophageal squamous cell carcinoma refractory or intolerant to previous chemotherapy (ATTRACTION-3): a multicentre, randomised, open-label, phase 3 trial

(2019) Ken Kato et al.   LANCET ONCOLOGY

Possibilities of Fucoidan Utilization in the Development of Pharmaceutical Dosage Forms

(2019) Aleksandra Citkowska et al.   Marine Drugs

Anti-Metabolic Syndrome Effects of Fucoidan from Fucus vesiculosus via Reactive Oxygen Species-Mediated Regulation of JNK, Akt, and AMPK Signaling

(2019) Xueliang Wang et al.   MOLECULES

T Cell Dysfunction in Cancer

(2018) Daniela S. Thommen et al.   CANCER CELL

Adjuvant Pembrolizumab versus Placebo in Resected Stage III Melanoma

(2018) Alexander M.M. Eggermont et al.   NEW ENGLAND JOURNAL OF MEDICINE

Development of PD-1 and PD-L1 inhibitors as a form of cancer immunotherapy: a comprehensive review of registration trials and future considerations

(2018) Jun Gong et al.   Journal for ImmunoTherapy of Cancer

Anti-PD-1 and Anti-CTLA-4 Therapies in Cancer: Mechanisms of Action, Efficacy, and Limitations

(2018) Judith A. Seidel et al.   Frontiers in Oncology

High response rate to PD-1 blockade in desmoplastic melanomas

(2018) Zeynep Eroglu et al.   NATURE

“Do We Know Jack” About JAK? A Closer Look at JAK/STAT Signaling Pathway

(2018) Emira Bousoik et al.   Frontiers in Oncology

Interleukin 2 Secretion by T Cells for Detection of Biologically Active Staphylococcal Enterotoxin Type E

(2017) Reuven Rasooly et al.   JOURNAL OF FOOD PROTECTION

Induction of p53-Independent Apoptosis and G1 Cell Cycle Arrest by Fucoidan in HCT116 Human Colorectal Carcinoma Cells

(2017) Hye Park et al.   Marine Drugs

Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors

(2017) Bertrand Routy et al.   SCIENCE

Combination Cancer Therapies with Immune Checkpoint Blockade: Convergence on Interferon Signaling

(2016) Andy J. Minn et al.   CELL

Impact of Mediterranean diet on metabolic syndrome, cancer and longevity

(2016) Nicola Di Daniele et al.   Oncotarget

Antitumor activity of fucoidan against diffuse large B cell lymphomain vitroandin vivo

(2015) Guang Yang et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Antitumor Effects of Fucoidan on Human Colon Cancer Cells via Activation of Akt Signaling

(2015) Yong-seok Han et al.   Biomolecules & Therapeutics

Fucoidan Suppresses the Growth of Human Acute Promyelocytic Leukemia Cells In Vitro and In Vivo

(2015) Farzaneh Atashrazm et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Therapies from Fucoidan: An Update

(2015) Janet Fitton et al.   Marine Drugs

Fucoidan and Cancer: A Multifunctional Molecule with Anti-Tumor Potential

(2015) Farzaneh Atashrazm et al.   Marine Drugs

Intestinal Absorption of Fucoidan Extracted from the Brown Seaweed, Cladosiphon okamuranus

(2014) Takeaki Nagamine et al.   Marine Drugs

Fucoidan as a Marine Anticancer Agent in Preclinical Development

(2014) Jong-Young Kwak   Marine Drugs

Fucoidan Can Function as an Adjuvant In Vivo to Enhance Dendritic Cell Maturation and Function and Promote Antigen-Specific T Cell Immune Responses

(2014) Jun-O Jin et al.   PLoS One

Hydrolysis of Fucoidan by Fucoidanase Isolated from the Marine Bacterium, Formosa algae

(2013) Artem Silchenko et al.   Marine Drugs

Fasting Cycles Retard Growth of Tumors and Sensitize a Range of Cancer Cell Types to Chemotherapy

(2012) C. Lee et al.   Science Translational Medicine

Fucoidan from Sargassum sp. and Fucus vesiculosus reduces cell viability of lung carcinoma and melanoma cells in vitro and activates natural killer cells in mice in vivo

(2011) Marcel Tutor Ale et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Therapies from Fucoidan; Multifunctional Marine Polymers

(2011) Janet Helen Fitton   Marine Drugs

Fucoidan present in brown algae induces apoptosis of human colon cancer cells

(2010) Eun Ji Kim et al.   BMC GASTROENTEROLOGY

Apoptosis Inducing Activity of Fucoidan in HCT-15 Colon Carcinoma Cells

(2009) Jae-Hee Hyun et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Ligand of scavenger receptor class A indirectly induces maturation of human blood dendritic cells via production of tumor necrosis factor- 

(2009) J.-O Jin et al.   BLOOD

Immunomodulatory effect of a Sophora subprosrate polysaccharide in mice

(2009) Xue-Hong Shuai et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES