IFN-γ is essential for alveolar macrophage–driven pulmonary inflammation in macrophage activation syndrome

IL-18 as a biomarker linking systemic juvenile idiopathic arthritis and macrophage activation syndrome

(2019) Shima Yasin et al.   RHEUMATOLOGY

Emergent high fatality lung disease in systemic juvenile arthritis

(2019) Vivian E Saper et al.   ANNALS OF THE RHEUMATIC DISEASES

Functional Regulation of Macrophage Phenotypes by MicroRNAs in Inflammatory Arthritis

(2019) Xiaoling Niu et al.   Frontiers in Immunology

Systemic Juvenile Idiopathic Arthritis–Associated Lung Disease: Characterization and Risk Factors

(2019) Grant S. Schulert et al.   Arthritis & Rheumatology

The Transcription Factor STAT6 Mediates Direct Repression of Inflammatory Enhancers and Limits Activation of Alternatively Polarized Macrophages

(2018) Zsolt Czimmerer et al.   IMMUNITY

Convergent pathways of the hyperferritinemic syndromes

(2018) Grant S Schulert et al.   INTERNATIONAL IMMUNOLOGY

The Activin A-Peroxisome Proliferator-Activated Receptor Gamma Axis Contributes to the Transcriptome of GM-CSF-Conditioned Human Macrophages

(2018) Concha Nieto et al.   Frontiers in Immunology

Toll-like receptor 9 activation potentiates interferon-γ-mediated immunopathology in a murine model of Macrophage Activation Syndrome

(2018) Lehn K. Weaver et al.   Arthritis & Rheumatology

Elevated circulating levels of interferon-γ and interferon-γ-induced chemokines characterise patients with macrophage activation syndrome complicating systemic juvenile idiopathic arthritis

(2016) Claudia Bracaglia et al.   ANNALS OF THE RHEUMATIC DISEASES

Revised classification of histiocytoses and neoplasms of the macrophage-dendritic cell lineages

(2016) J.-F. Emile et al.   BLOOD

NFKB1: a suppressor of inflammation, ageing and cancer

(2016) Tyrell Cartwright et al.   FEBS Journal

The double knockout of Bach1 and Bach2 in mice reveals shared compensatory mechanisms in regulating alveolar macrophage function and lung surfactant homeostasis

(2016) Risa Ebina-Shibuya et al.   JOURNAL OF BIOCHEMISTRY

Macrophage activation syndrome in the era of biologic therapy

(2016) Alexei A. Grom et al.   Nature Reviews Rheumatology

TLR9-mediated inflammation drives a Ccr2-independent peripheral monocytosis through enhanced extramedullary monocytopoiesis

(2016) Lehn K. Weaver et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pathogenesis of Macrophage Activation Syndrome and Potential for Cytokine- Directed Therapies

(2015) Grant S. Schulert et al.   Annual Review of Medicine

Transcription Factors STAT6 and KLF4 Implement Macrophage Polarization via the Dual Catalytic Powers of MCPIP

(2015) Nidhi Kapoor et al.   JOURNAL OF IMMUNOLOGY

Cytokines in systemic juvenile idiopathic arthritis and haemophagocytic lymphohistiocytosis: tipping the balance between interleukin-18 and interferon-γ

(2015) Karen Put et al.   RHEUMATOLOGY

Heme oxygenase-1 and anti-inflammatory M2 macrophages

(2014) Yuji Naito et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Glucocorticoid receptor coordinates transcription factor-dominated regulatory network in macrophages

(2014) Yurii Chinenov et al.   BMC GENOMICS

Interferon-γ Mediates Anemia but Is Dispensable for Fulminant Toll-like Receptor 9-Induced Macrophage Activation Syndrome and Hemophagocytosis in Mice

(2013) Scott W. Canna et al.   ARTHRITIS AND RHEUMATISM

Alveolar macrophages of GM-CSF knockout mice exhibit mixed M1 and M2 phenotypes

(2013) Heidi Dalrymple et al.   BMC IMMUNOLOGY

miR-125a-5p Regulates Differential Activation of Macrophages and Inflammation

(2013) Sami Banerjee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inherited defects causing hemophagocytic lymphohistiocytic syndrome

(2012) Geneviève de Saint Basile et al.   Annals of the New York Academy of Sciences

The limited role of interferon-γ in systemic juvenile idiopathic arthritis cannot be explained by cellular hyporesponsiveness

(2012) Keith A. Sikora et al.   ARTHRITIS AND RHEUMATISM

Pulmonary Hypertension and Other Potentially Fatal Pulmonary Complications in Systemic Juvenile Idiopathic Arthritis

(2012) Yukiko Kimura et al.   ARTHRITIS CARE & RESEARCH

Hemophagocytic lymphohistiocytosis

(2011) Kimberly Risma et al.   CURRENT OPINION IN PEDIATRICS

Repeated TLR9 stimulation results in macrophage activation syndrome–like disease in mice

(2011) Edward M. Behrens et al.   JOURNAL OF CLINICAL INVESTIGATION

A multicentre, randomised, double-blind, placebo-controlled trial with the interleukin-1 receptor antagonist anakinra in patients with systemic-onset juvenile idiopathic arthritis (ANAJIS trial)

(2010) P. Quartier et al.   ANNALS OF THE RHEUMATIC DISEASES

Role of Kruppel-like factors in leukocyte development, function, and disease

(2010) Z. Cao et al.   BLOOD

The molecular basis of pulmonary alveolar proteinosis

(2010) Brenna Carey et al.   CLINICAL IMMUNOLOGY

Neutrophil-mediated lung permeability and host defense proteins

(2009) Stephen P. Kantrow et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Mice with a Selective Impairment of IFN-  Signaling in Macrophage Lineage Cells Demonstrate the Critical Role of IFN- -Activated Macrophages for the Control of Protozoan Parasitic Infections In Vivo

(2009) J. E. Lykens et al.   JOURNAL OF IMMUNOLOGY

A Griscelli syndrome type 2 murine model of hemophagocytic lymphohistiocytosis (HLH)

(2008) Jana Pachlopnik Schmid et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Familial pulmonary alveolar proteinosis caused by mutations inCSF2RA

(2008) Takuji Suzuki et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Pulmonary alveolar proteinosis caused by deletion of the GM-CSFRα gene in the X chromosome pseudoautosomal region 1

(2008) Margarita Martinez-Moczygemba et al.   JOURNAL OF EXPERIMENTAL MEDICINE