Antisense oligonucleotide treatment rescues UBE3A expression and multiple phenotypes of an Angelman syndrome mouse model

Angelman Syndrome: From Mouse Models to Therapy

(2020) Diana C. Rotaru et al.   NEUROSCIENCE

Cas9 gene therapy for Angelman syndrome traps Ube3a-ATS long non-coding RNA

(2020) Justin M. Wolter et al.   NATURE

Assessing the requirements of prenatal UBE3A expression for rescue of behavioral phenotypes in a mouse model for Angelman syndrome

(2020) Monica Sonzogni et al.   Molecular Autism

Differential Timing and Coordination of Neurogenesis and Astrogenesis in Developing Mouse Hippocampal Subregions

(2020) Allison M. Bond et al.   Brain Sciences

Delayed loss of UBE3A reduces the expression of Angelman syndrome-associated phenotypes

(2019) Monica Sonzogni et al.   Molecular Autism

Loss of nuclear UBE3A causes electrophysiological and behavioral deficits in mice and is associated with Angelman syndrome

(2019) Rossella Avagliano Trezza et al.   NATURE NEUROSCIENCE

Locked nucleic acid: modality, diversity, and drug discovery

(2018) Peter H. Hagedorn et al.   DRUG DISCOVERY TODAY

A behavioral test battery for mouse models of Angelman syndrome: a powerful tool for testing drugs and novel Ube3a mutants

(2018) Monica Sonzogni et al.   Molecular Autism

Precisely measured protein lifetimes in the mouse brain reveal differences across tissues and subcellular fractions

(2018) Eugenio F. Fornasiero et al.   Nature Communications

Decreased Axon Caliber Underlies Loss of Fiber Tract Integrity, Disproportional Reductions in White Matter Volume, and Microcephaly in Angelman Syndrome Model Mice

(2017) Matthew C. Judson et al.   JOURNAL OF NEUROSCIENCE

Antisense Oligonucleotide-Based Therapy for Neuromuscular Disease

(2017) Valentina Sardone et al.   MOLECULES

Antisense oligonucleotides: the next frontier for treatment of neurological disorders

(2017) Carlo Rinaldi et al.   Nature Reviews Neurology

Antisense Oligonucleotides: Translation from Mouse Models to Human Neurodegenerative Diseases

(2017) Kathleen M. Schoch et al.   NEURON

Angelman syndrome — insights into a rare neurogenetic disorder

(2016) Karin Buiting et al.   Nature Reviews Neurology

Morphological maturation of the mouse brain: An in vivo MRI and histology investigation

(2016) Luam Hammelrath et al.   NEUROIMAGE

Ube3a reinstatement identifies distinct developmental windows in a murine Angelman syndrome model

(2015) Sara Silva-Santos et al.   JOURNAL OF CLINICAL INVESTIGATION

Epigenetic regulation of UBE3A and roles in human neurodevelopmental disorders

(2015) Janine M LaSalle et al.   Epigenomics

Towards a therapy for Angelman syndrome by targeting a long non-coding RNA

(2014) Linyan Meng et al.   NATURE

Angelman syndrome in Denmark. Birth incidence, genetic findings, and age at diagnosis

(2013) Line Granild Bie Mertz et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Truncation of Ube3a-ATS Unsilences Paternal Ube3a and Ameliorates Behavioral Defects in the Angelman Syndrome Mouse Model

(2013) Linyan Meng et al.   PLoS Genetics

Comparative analysis of deutocerebral neuropils in Chilopoda (Myriapoda): implications for the evolution of the arthropod olfactory system and support for the Mandibulata concept

(2012) Andy Sombke et al.   BMC NEUROSCIENCE

Ube3a-ATS is an atypical RNA polymerase II transcript that represses the paternal expression of Ube3a

(2012) Linyan Meng et al.   HUMAN MOLECULAR GENETICS

Angelman syndrome: insights into genomic imprinting and neurodevelopmental phenotypes

(2011) Angela M. Mabb et al.   TRENDS IN NEUROSCIENCES