Endothelial deficiency of insulin-like growth factor-1 receptor (IGF1R) impairs neurovascular coupling responses in mice, mimicking aspects of the brain aging phenotype
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Endothelial deficiency of insulin-like growth factor-1 receptor (IGF1R) impairs neurovascular coupling responses in mice, mimicking aspects of the brain aging phenotype
Authors
Keywords
-
Journal
GeroScience
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-08-12
DOI
10.1007/s11357-021-00405-2
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- IGF1R signaling regulates astrocyte-mediated neurovascular coupling in mice: implications for brain aging
- (2021) Stefano Tarantini et al. GeroScience
- Mechanisms of Vascular Aging, A Geroscience Perspective
- (2020) Zoltan Ungvari et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Insulin-like growth factor-1 overexpression increases long-term survival of posttrauma-born hippocampal neurons while inhibiting ectopic migration following traumatic brain injury
- (2020) Erica L. Littlejohn et al. Acta Neuropathologica Communications
- Circulating anti-geronic factors from heterochonic parabionts promote vascular rejuvenation in aged mice: transcriptional footprint of mitochondrial protection, attenuation of oxidative stress, and rescue of endothelial function by young blood
- (2020) Tamas Kiss et al. GeroScience
- Time-restricted feeding (TRF) for prevention of age-related vascular cognitive impairment and dementia
- (2020) Priya Balasubramanian et al. AGEING RESEARCH REVIEWS
- Hormone replacement therapy attenuates hearing loss: Mechanisms involving estrogen and the IGF-1 pathway
- (2019) Tanika T. Williamson et al. AGING CELL
- Effects of IGF‐1 isoforms on muscle growth and sarcopenia
- (2019) Francesca Ascenzi et al. AGING CELL
- IGF-1 and cardiovascular disease
- (2019) Yusuke Higashi et al. GROWTH HORMONE & IGF RESEARCH
- Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice
- (2019) Stefano Tarantini et al. Redox Biology
- Loss of Insulin‐like Growth Factor‐1 Signaling in Astrocytes Disrupts Glutamate Handling
- (2019) Disha Prabhu et al. JOURNAL OF NEUROCHEMISTRY
- The role of exercise in the reversal of IGF-1 deficiencies in microvascular rarefaction and hypertension
- (2019) Amani M. Norling et al. GeroScience
- Treatment with the mitochondrial-targeted antioxidant peptide SS-31 rescues neurovascular coupling responses and cerebrovascular endothelial function and improves cognition in aged mice
- (2018) Stefano Tarantini et al. AGING CELL
- IGF-1 Deficiency Promotes Pathological Remodeling of Cerebral Arteries: A Potential Mechanism Contributing to the Pathogenesis of Intracerebral Hemorrhages in Aging
- (2018) Gabor A Fulop et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Insulin-like growth factor receptor signaling regulates working memory, mitochondrial metabolism, and amyloid-β uptake in astrocytes
- (2018) Sreemathi Logan et al. Molecular Metabolism
- Mechanisms of Vascular Aging
- (2018) Zoltan Ungvari et al. CIRCULATION RESEARCH
- Insulin-like Growth Factor (IGF)-1 treatment stabilizes the microvascular cytoskeleton under ischemic conditions
- (2018) Shameena Bake et al. EXPERIMENTAL NEUROLOGY
- Impaired neurovascular coupling in aging and Alzheimer's disease: Contribution of astrocyte dysfunction and endothelial impairment to cognitive decline
- (2017) Stefano Tarantini et al. EXPERIMENTAL GERONTOLOGY
- Astrocyte-specific insulin-like growth factor-1 gene transfer in aging female rats improves stroke outcomes
- (2017) Andre K. Okoreeh et al. GLIA
- Trajectories of IGF-I Predict Mortality in Older Adults: The Cardiovascular Health Study
- (2017) Jason L Sanders et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Insulin-Like Growth Factor-1 and Neuroinflammation
- (2017) Jose L. Labandeira-Garcia et al. Frontiers in Aging Neuroscience
- Pharmacologically induced impairment of neurovascular coupling responses alters gait coordination in mice
- (2017) Stefano Tarantini et al. GeroScience
- Circulating IGF-1 deficiency exacerbates hypertension-induced microvascular rarefaction in the mouse hippocampus and retrosplenial cortex: implications for cerebromicrovascular and brain aging
- (2016) Stefano Tarantini et al. AGE
- Insulin-like growth factor-I gene therapy increases hippocampal neurogenesis, astrocyte branching and improves spatial memory in female aging rats
- (2016) Joaquín Pardo et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- IGF-1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging
- (2015) Peter Toth et al. AGING CELL
- Purinergic glio-endothelial coupling during neuronal activity: role of P2Y1 receptors and eNOS in functional hyperemia in the mouse somatosensory cortex
- (2015) Peter Toth et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Pharmacologically-Induced Neurovascular Uncoupling is Associated with Cognitive Impairment in Mice
- (2015) Stefano Tarantini et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Insulin and IGF1 signalling pathways in human astrocytes in vitro and in vivo; characterisation, subcellular localisation and modulation of the receptors
- (2015) Claire J. Garwood et al. Molecular Brain
- Combined Effect of Insulin-Like Growth Factor-1 and CC Chemokine Ligand 2 on Angiogenic Events in Endothelial Cells
- (2015) Iana Mayane Mendes Nicácio Viana et al. PLoS One
- Vitamin D modulates the association of circulating insulin-like growth factor-1 with carotid artery intima-media thickness
- (2014) Pietro Ameri et al. ATHEROSCLEROSIS
- IGF-1 Deficiency Impairs Cerebral Myogenic Autoregulation in Hypertensive Mice
- (2014) Peter Toth et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- The Relationship between Serum Insulin-Like Growth Factor I Levels and Ischemic Stroke Risk
- (2014) Xiang Dong et al. PLoS One
- Resveratrol treatment rescues neurovascular coupling in aged mice: role of improved cerebromicrovascular endothelial function and downregulation of NADPH oxidase
- (2013) Peter Toth et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Small for Gestational Age and Intrauterine Growth Restriction Decreases Cognitive Function in Young Adults
- (2013) Gro C.C. Løhaugen et al. JOURNAL OF PEDIATRICS
- Astrocyte-induced cortical vasodilation is mediated by D-serine and endothelial nitric oxide synthase
- (2013) J. L. L. Stobart et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Insulin-like growth factor-1 in CNS and cerebrovascular aging
- (2013) William E. Sonntag et al. Frontiers in Aging Neuroscience
- Loss of serum IGF-I input to the brain as an early biomarker of disease onset in Alzheimer mice
- (2013) A Trueba-Sáiz et al. Translational Psychiatry
- Novel Role of the IGF-1 Receptor in Endothelial Function and Repair: Studies in Endothelium-Targeted IGF-1 Receptor Transgenic Mice
- (2012) H. Imrie et al. DIABETES
- Aging, Atherosclerosis, and IGF-1
- (2012) Y. Higashi et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- The Emerging Role of IGF-1 Deficiency in Cardiovascular Aging: Recent Advances
- (2012) Z. Ungvari et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- The many faces of insulin-like peptide signalling in the brain
- (2012) Ana M. Fernandez et al. NATURE REVIEWS NEUROSCIENCE
- IGF-1 Has Plaque-Stabilizing Effects in Atherosclerosis by Altering Vascular Smooth Muscle Cell Phenotype
- (2011) Jan H. von der Thüsen et al. AMERICAN JOURNAL OF PATHOLOGY
- Low circulating insulin-like growth factor I increases atherosclerosis in ApoE-deficient mice
- (2011) Shaw-Yung Shai et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- IGF1R mutations as cause of SGA
- (2011) J. Klammt et al. BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM
- Energy-preserving effects of IGF-1 antagonize starvation-induced cardiac autophagy
- (2011) Rodrigo Troncoso et al. CARDIOVASCULAR RESEARCH
- The Insulin-Like Growth Factor-1 Receptor Is a Negative Regulator of Nitric Oxide Bioavailability and Insulin Sensitivity in the Endothelium
- (2011) A. Abbas et al. DIABETES
- Endothelial Function and Mechanical Arterial Properties in Children Born Small for Gestational Age: Comparison with Obese Children
- (2011) B. Jouret et al. Hormone Research in Paediatrics
- Reduced brain insulin-like growth factor I function during aging
- (2011) Alexandre Pastoris Muller et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- IGF-I and the aging mammalian brain
- (2010) J. Piriz et al. EXPERIMENTAL GERONTOLOGY
- Up-regulation of the tight-junction protein ZO-1 by substance P and IGF-1 in A431 cells
- (2009) Ji-Ae Ko et al. CELL BIOCHEMISTRY AND FUNCTION
- Polymorphisms in the IGF1 and IGF1R genes and children born small for gestational age: results of large population studies
- (2008) W.A. Ester et al. BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM
- Unknown
- (2008) Per Humpert et al. MOLECULAR MEDICINE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started