Loss of serum IGF-I input to the brain as an early biomarker of disease onset in Alzheimer mice

Modeling Alzheimer’s Disease with iPSCs Reveals Stress Phenotypes Associated with Intracellular Aβ and Differential Drug Responsiveness

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Alternations of central insulin-like growth factor-1 sensitivity in APP/PS1 transgenic mice and neuronal models

(2013) Bing Zhang et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Relationship between Plasma Analytes and SPARE-AD Defined Brain Atrophy Patterns in ADNI

(2013) Jon B. Toledo et al.   PLoS One

Serum but not cerebrospinal fluid levels of insulin-like growth factor-I (IGF-I) and IGF-binding protein-3 (IGFBP-3) are increased in Alzheimer's disease

(2013) Per Johansson et al.   PSYCHONEUROENDOCRINOLOGY

Effects of Growth Hormone–Releasing Hormone on Cognitive Function in Adults With Mild Cognitive Impairment and Healthy Older Adults

(2012) Laura D. Baker et al.   ARCHIVES OF NEUROLOGY

Demonstrated brain insulin resistance in Alzheimer’s disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline

(2012) Konrad Talbot et al.   JOURNAL OF CLINICAL INVESTIGATION

The many faces of insulin-like peptide signalling in the brain

(2012) Ana M. Fernandez et al.   NATURE REVIEWS NEUROSCIENCE

PEGylation enhances the therapeutic potential for insulin-like growth factor I in central nervous system disorders

(2011) S. Saenger et al.   GROWTH HORMONE & IGF RESEARCH

Regulation of the phosphatase calcineurin by insulin-like growth factor I unveils a key role of astrocytes in Alzheimer's pathology

(2011) A M Fernandez et al.   MOLECULAR PSYCHIATRY

Age-related changes in the default mode network are more advanced in Alzheimer disease

(2011) D. T. Jones et al.   NEUROLOGY

Blood-Borne Amyloid-  Dimer Correlates with Clinical Markers of Alzheimer's Disease

(2010) V. L. Villemagne et al.   JOURNAL OF NEUROSCIENCE

CSF Biomarkers in Prediction of Cerebral and Clinical Change in Mild Cognitive Impairment and Alzheimer's Disease

(2010) A. M. Fjell et al.   JOURNAL OF NEUROSCIENCE

Neuronal Activity Drives Localized Blood-Brain-Barrier Transport of Serum Insulin-like Growth Factor-I into the CNS

(2010) Takeshi Nishijima et al.   NEURON

Multimodal techniques for diagnosis and prognosis of Alzheimer's disease

(2009) Richard J. Perrin et al.   NATURE

Homocysteine and Cognitive Impairment

(2008) Isabel Sala et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Defects in IGF-1 receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-1 and insulin signalling

(2008) Aileen M. Moloney et al.   NEUROBIOLOGY OF AGING

Amyloid beta oligomers induce impairment of neuronal insulin receptors

(2007) Wei-Qin Zhao et al.   FASEB JOURNAL