Ultrasound-Mediated Blood-Brain Barrier Opening Improves Whole Brain Gene Delivery in Mice

Adeno-Associated Virus Vector for Central Nervous System Gene Therapy

(2021) Danqing Zhu et al.   TRENDS IN MOLECULAR MEDICINE

Destination Amyotrophic Lateral Sclerosis

(2021) Matt Keon et al.   Frontiers in Neurology

Sonoselective transfection of cerebral vasculature without blood–brain barrier disruption

(2020) Catherine M. Gorick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Challenge of Gene Therapy for Neurological Diseases: Strategies and Tools to Achieve Efficient Delivery to the Central Nervous System

(2020) Françoise Piguet et al.   HUMAN GENE THERAPY

Impact of blood-brain barrier permeabilization induced by ultrasound associated to microbubbles on the brain delivery and kinetics of cetuximab: An immunoPET study using 89Zr-cetuximab

(2020) Vu Long Tran et al.   JOURNAL OF CONTROLLED RELEASE

Recent Advances on Ultrasound Contrast Agents for Blood-Brain Barrier Opening with Focused Ultrasound

(2020) Ambre Dauba et al.   Pharmaceutics

Severe offtarget effects following intravenous delivery of AAV9-MECP2 in a female mouse model of Rett syndrome

(2020) Valerie Matagne et al.   NEUROBIOLOGY OF DISEASE

Gene Therapy Tools for Brain Diseases

(2019) Selene Ingusci et al.   Frontiers in Pharmacology

The autonomic nervous system and the brainstem: A fundamental role or the background actors for consciousness generation? Hypothesis, evidence, and future directions for rehabilitation and theoretical approaches

(2019) Davide Sattin et al.   Brain and Behavior

Intra-cerebrospinal fluid antibiotics to treat central nervous system infections: A review and update

(2018) Oliver D. Mrowczynski et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Safe and stable noninvasive focal gene delivery to the mammalian brain following focused ultrasound

(2018) Mihaela A. Stavarache et al.   JOURNAL OF NEUROSURGERY

Combined Gene Therapy to Reduce the Neuronal Damage in the Mouse Model of Focal Ischemic Injury

(2018) Lior Molcho et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Acoustic Transmission Factor through the Rat Skull as a Function of Body Mass, Frequency and Position

(2018) Matthieu Gerstenmayer et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

Clinical Gene Therapy for Neurodegenerative Diseases: Past, Present, and Future

(2017) Françoise Piguet et al.   HUMAN GENE THERAPY

Pleiotrophin regulates microglia-mediated neuroinflammation

(2017) Rosalía Fernández-Calle et al.   Journal of Neuroinflammation

A codon-optimized Mecp2 transgene corrects breathing deficits and improves survival in a mouse model of Rett syndrome

(2017) Valerie Matagne et al.   NEUROBIOLOGY OF DISEASE

Cellular selectivity of AAV serotypes for gene delivery in neurons and astrocytes by neonatal intracerebroventricular injection

(2017) Sean L. Hammond et al.   PLoS One

Brain and Peripheral Atypical Inflammatory Mediators Potentiate Neuroinflammation and Neurodegeneration

(2017) Duraisamy Kempuraj et al.   Frontiers in Cellular Neuroscience

Acute effects of focused ultrasound-induced increases in blood-brain barrier permeability on rat microvascular transcriptome

(2017) Dallan McMahon et al.   Scientific Reports

Adeno-Associated Virus-Based Gene Therapy for CNS Diseases

(2016) Michaël Hocquemiller et al.   HUMAN GENE THERAPY

The Blood–Brain Barrier

(2015) Richard Daneman et al.   Cold Spring Harbor Perspectives in Biology

Role of GFAP in CNS injuries

(2014) Michael Brenner   NEUROSCIENCE LETTERS

Strong Cortical and Spinal Cord Transduction After AAV7 and AAV9 Delivery into the Cerebrospinal Fluid of Nonhuman Primates

(2013) Lluis Samaranch et al.   HUMAN GENE THERAPY

The Choroid Plexus and Cerebrospinal Fluid: Emerging Roles in Development, Disease, and Therapy

(2013) M. K. Lehtinen et al.   JOURNAL OF NEUROSCIENCE

Noninvasive and Targeted Gene Delivery into the Brain Using Microbubble-Facilitated Focused Ultrasound

(2013) Po-Hung Hsu et al.   PLoS One

Focal Delivery of AAV2/1-transgenes Into the Rat Brain by Localized Ultrasound-induced BBB Opening

(2013) Angelika Alonso et al.   Molecular Therapy-Nucleic Acids

Targeted Delivery of Self-Complementary Adeno-Associated Virus Serotype 9 to the Brain, Using Magnetic Resonance Imaging-Guided Focused Ultrasound

(2012) Emmanuel Thévenot et al.   HUMAN GENE THERAPY

Correction of Neurological Disease of Mucopolysaccharidosis IIIB in Adult Mice by rAAV9 Trans-Blood–Brain Barrier Gene Delivery

(2011) Haiyan Fu et al.   MOLECULAR THERAPY

Production, Purification and Characterization of Adeno-Associated Vectors

(2010) Eduard Ayuso et al.   CURRENT GENE THERAPY

Controlling brain tumor growth by intraventricular administration of an AAV vector encoding IFN-β

(2009) D H Meijer et al.   CANCER GENE THERAPY

The Basic Helix-Loop-Helix Transcription Factor Olig2 Is Critical for Reactive Astrocyte Proliferation after Cortical Injury

(2008) Y. Chen et al.   JOURNAL OF NEUROSCIENCE

Needle Size and Injection Rate Impact Microbubble Contrast Agent Population

(2008) Esra Talu et al.   ULTRASOUND IN MEDICINE AND BIOLOGY