Combined Gene Therapy to Reduce the Neuronal Damage in the Mouse Model of Focal Ischemic Injury

Monocyte depletion early after stroke promotes neurogenesis from endogenous neural stem cells in adult brain

(2017) Cecilia Laterza et al.   EXPERIMENTAL NEUROLOGY

Selective knockout of astrocytic Na+ /H+ exchanger isoform 1 reduces astrogliosis, BBB damage, infarction, and improves neurological function after ischemic stroke

(2017) Gulnaz Begum et al.   GLIA

Neuroprotection in acute stroke: targeting excitotoxicity, oxidative and nitrosative stress, and inflammation

(2016) Ángel Chamorro et al.   LANCET NEUROLOGY

A novel nuclear factor erythroid 2-related factor 2 (Nrf2) activator RS9 attenuates brain injury after ischemia reperfusion in mice

(2016) Keita Yamauchi et al.   NEUROSCIENCE

Astrocyte-derived interleukin-15 exacerbates ischemic brain injury via propagation of cellular immunity

(2016) Minshu Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glutamate transporter EAAT2: regulation, function, and potential as a therapeutic target for neurological and psychiatric disease

(2015) Kou Takahashi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Ectopic Muscle Expression of Neurotrophic Factors Improves Recovery After Nerve Injury

(2015) Micaela Johanna Glat et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Multifactorial Gene Therapy Enhancing the Glutamate Uptake System and Reducing Oxidative Stress Delays Symptom Onset and Prolongs Survival in the SOD1-G93A ALS Mouse Model

(2015) Chen Benkler et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Time course of neuronal death following endothelin-1 induced focal ischemia in rats

(2015) Carine Nguemeni et al.   JOURNAL OF NEUROSCIENCE METHODS

Temporal activation of Nrf2 in the penumbra and Nrf2 activator-mediated neuroprotection in ischemia–reperfusion injury

(2014) Toshinori Takagi et al.   FREE RADICAL BIOLOGY AND MEDICINE

Excitotoxicity and stroke: Identifying novel targets for neuroprotection

(2013) Ted Weita Lai et al.   PROGRESS IN NEUROBIOLOGY

Glutamate transporter EAAT2: a new target for the treatment of neurodegenerative diseases

(2012) Chien-Liang Glenn Lin et al.   Future Medicinal Chemistry

Targeted Over-Expression of Glutamate Transporter 1 (GLT-1) Reduces Ischemic Brain Injury in a Rat Model of Stroke

(2011) Brandon K. Harvey et al.   PLoS One

Curcumin upregulates transcription factor Nrf2, HO-1 expression and protects rat brains against focal ischemia

(2009) Chenhui Yang et al.   BRAIN RESEARCH

Oxidative Stress-Induced Necrotic Cell Death via Mitochondira-Dependent Burst of Reactive Oxygen Species

(2009) Kyungsun Choi et al.   CURRENT NEUROVASCULAR RESEARCH

Gain-of-function variant in GLUD2 glutamate dehydrogenase modifies Parkinson's disease onset

(2009) Andreas Plaitakis et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

The Nrf2-Antioxidant Response Element Signaling Pathway and Its Activation by Oxidative Stress

(2009) Truyen Nguyen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inflammatory mechanisms in ischemic stroke: therapeutic approaches

(2009) Shaheen E Lakhan et al.   Journal of Translational Medicine

Mouse model of focal cerebral ischemia using endothelin-1

(2008) Nobutaka Horie et al.   JOURNAL OF NEUROSCIENCE METHODS

Selective overexpression of excitatory amino acid transporter 2 (EAAT2) in astrocytes enhances neuroprotection from moderate but not severe hypoxia–ischemia

(2008) M.L. Weller et al.   NEUROSCIENCE

Nrf2 as a Master Redox Switch in Turning on the Cellular Signaling Involved in the Induction of Cytoprotective Genes by Some Chemopreventive Phytochemicals

(2008) Young-Joon Surh et al.   PLANTA MEDICA

Neuroprotection: Still Achievable in Humans

(2008) Geoffrey A. Donnan et al.   STROKE