Impact of blood-brain barrier permeabilization induced by ultrasound associated to microbubbles on the brain delivery and kinetics of cetuximab: An immunoPET study using 89Zr-cetuximab

Blood-Brain Barrier Opening in Primary Brain Tumors with Non-invasive MR-Guided Focused Ultrasound: A Clinical Safety and Feasibility Study

(2019) Todd Mainprize et al.   Scientific Reports

Pathological and Molecular Features of Glioblastoma and Its Peritumoral Tissue

(2019) Alessio D’Alessio et al.   Cancers

Ultrasound-mediated blood-brain barrier opening enhances delivery of therapeutically relevant formats of a tau-specific antibody

(2019) Phillip W. Janowicz et al.   Scientific Reports

Trends and Challenges in Tumor Anti-Angiogenic Therapies

(2019) József Jászai et al.   Cells

Empirical and Theoretical Characterization of the Diffusion Process of Different Gadolinium-Based Nanoparticles within the Brain Tissue after Ultrasound-Induced Permeabilization of the Blood-Brain Barrier

(2019) Allegra Conti et al.   Contrast Media & Molecular Imaging

Epidermal growth factor receptor and ligand family expression and activity in glioblastoma

(2018) Caroline von Achenbach et al.   JOURNAL OF NEUROCHEMISTRY

Epidermal growth factor receptor and EGFRvIII in glioblastoma: signaling pathways and targeted therapies

(2018) Zhenyi An et al.   ONCOGENE

Current Challenges and Opportunities in Treating Glioblastoma

(2018) Andrea Shergalis et al.   PHARMACOLOGICAL REVIEWS

Mechanisms of enhanced drug delivery in brain metastases with focused ultrasound-induced blood–tumor barrier disruption

(2018) Costas D. Arvanitis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Physical blood-brain barrier disruption induced by focused ultrasound does not overcome the transporter-mediated efflux of erlotinib

(2018) Sébastien Goutal et al.   JOURNAL OF CONTROLLED RELEASE

89Zr-atezolizumab imaging as a non-invasive approach to assess clinical response to PD-L1 blockade in cancer

(2018) Frederike Bensch et al.   NATURE MEDICINE

Whole body PD-1 and PD-L1 positron emission tomography in patients with non-small-cell lung cancer

(2018) A. N. Niemeijer et al.   Nature Communications

Emerging functions of the EGFR in cancer

(2017) Sara Sigismund et al.   Molecular Oncology

Disrupting the blood–brain barrier with focused ultrasound: Perspectives on inflammation and regeneration

(2017) Joseph Silburt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epidermal growth factor receptor in glioblastoma

(2017) Hongsheng Xu et al.   Oncology Letters

Diphenhydramine as a selective probe to study H+-antiporter function at the blood–brain barrier: Application to [11C]diphenhydramine positron emission tomography imaging

(2016) Sylvain Auvity et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Focused Ultrasound Enhances Central Nervous System Delivery of Bevacizumab for Malignant Glioma Treatment

(2016) Hao-Li Liu et al.   RADIOLOGY

Antibody Approaches To Treat Brain Diseases

(2016) Vera Neves et al.   TRENDS IN BIOTECHNOLOGY

Probing the extracellular diffusion of antibodies in brain using in vivo integrative optical imaging and ex vivo fluorescence imaging

(2015) Daniel J. Wolak et al.   JOURNAL OF CONTROLLED RELEASE

Gliomas and the vascular fragility of the blood brain barrier

(2014) Luiz Gustavo Dubois et al.   Frontiers in Cellular Neuroscience

Efflux of monoclonal antibodies from rat brain by neonatal Fc receptor, FcRn

(2013) Philip R. Cooper et al.   BRAIN RESEARCH

Targeted delivery of antibody-based therapeutic and imaging agents to CNS tumors: crossing the blood–brain barrier divide

(2013) Ann-Marie Chacko et al.   Expert Opinion on Drug Delivery

Antibody biodistribution coefficients

(2013) Dhaval K. Shah et al.   mAbs

Ultrasound-Induced Blood-Brain Barrier Opening

(2012) Elisa E. Konofagou et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Comparative analysis of binding affinities to epidermal growth factor receptor of monoclonal antibodies nimotuzumab and cetuximab using different experimental animal models

(2011) N. Ledón et al.   PLACENTA

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

Radiolabeled cetuximab: Dose optimization for epidermal growth factor receptor imaging in a head-and-neck squamous cell carcinoma model

(2010) Bianca A.W. Hoeben et al.   INTERNATIONAL JOURNAL OF CANCER

Conjugation and radiolabeling of monoclonal antibodies with zirconium-89 for PET imaging using the bifunctional chelate p-isothiocyanatobenzyl-desferrioxamine

(2010) Maria J W D Vosjan et al.   Nature Protocols

Stratified phase II trial of cetuximab in patients with recurrent high-grade glioma

(2009) B. Neyns et al.   ANNALS OF ONCOLOGY

Epidermal growth factor receptor in relation to tumor development: EGFR gene and cancer

(2009) Tetsuya Mitsudomi et al.   FEBS Journal

The biological properties of cetuximab

(2008) Bruno Vincenzi et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Pulsed High-Intensity Focused Ultrasound Enhances Uptake of Radiolabeled Monoclonal Antibody to Human Epidermoid Tumor in Nude Mice

(2008) A. Khaibullina et al.   JOURNAL OF NUCLEAR MEDICINE